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ActiveNational Institutes of Health (NIH) · 2026

Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science

Quick Facts

Agency
National Institutes of Health (NIH)
Funding
Varies ($250,000 - $500,000)
Deadline
Rolling (Rolling / Open)
Status
Active
Eligibility
Higher education institutions, nonprofits, small businesses, state/local governments

About This Grant

Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science is sponsored by National Institutes of Health (NIH). Supports AI applications in biomedical and behavioral health, including therapeutic AI for pediatric mental health.

Official opportunity description and requirements excerpt:

Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science (SCH) | NSF - U.S. National Science Foundation An official website of the United States government Official websites use .gov A .gov website belongs to an official government organization in the United States. Secure .gov websites use HTTPS. or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites. Research Experiences for Undergraduates For Early-Career Researchers Proposal & Award Policies & Procedures Guide (PAPPG) How We Make Funding Decisions Request a Change to Your Award Proposal & Award Policies & Procedures Guide (PAPPG) NSF Public Access Repository Who to Contact With Questions Facilities and Infrastructure Updates on NSF Priorities Our Directorates & Offices Biological Sciences (BIO) Computer & Information Science & Engineering (CISE) Integrative Activities (OIA) International Science & Engineering (OISE) Mathematical & Physical Sciences (MPS) Social, Behavioral & Economic Sciences (SBE) Technology, Innovation & Partnerships (TIP) National Center for Science & Engineering Statistics (NCSES) National Science Board (NSB) Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science (SCH) Status: Waiting for new publication Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science (SCH) NSF's implementation of the revised 2 CFR NSF Financial Assistance awards (grants and cooperative agreements) made on or after October 1, 2024, will be subject to the applicable set of award conditions, dated October 1, 2024, available on the NSF website . These terms and conditions are consistent with the revised guidance specified in the OMB Guidance for Federal Financial Assistance published in the Federal Register on April 22, 2024. Important information for proposers All proposals must be submitted in accordance with the requirements specified in this funding opportunity and in the NSF Proposal & Award Policies & Procedures Guide (PAPPG) that is in effect for the relevant due date to which the proposal is being submitted. It is the responsibility of the proposer to ensure that the proposal meets these requirements. Submitting a proposal prior to a specified deadline does not negate this requirement. Updates to NSF Research Security Policies On July 10, 2025, NSF issued an Important Notice providing updates to the agency's research security policies, including a research security training requirement, Malign Foreign Talent Recruitment Program annual certification requirement, prohibition on Confucius institutes and an updated FFDR reporting and submission timeline. Supports high-risk, high-reward interdisciplinary research that combines computing, engineering, data science and behavioral and cognitive sciences to tackle

Application snapshot: target deadline rolling deadlines or periodic funding windows; published funding information Varies ($250,000 - $500,000); eligibility guidance Higher education institutions, nonprofits, small businesses, state/local governments

Use the official notice and source links for final requirements, attachment checklists, allowable costs, and submission instructions before applying.

View Original RFP

Official Opportunity Details

Extracted from the official opportunity page/RFP to help you evaluate fit faster.

Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science (SCH) | NSF - U. S. National Science Foundation An official website of the United States government Official websites use .

gov A . gov website belongs to an official government organization in the United States. Secure .

gov websites use HTTPS. or https:// means you've safely connected to the . gov website.

Share sensitive information only on official, secure websites.

Research Experiences for Undergraduates For Early-Career Researchers Proposal & Award Policies & Procedures Guide (PAPPG) How We Make Funding Decisions Request a Change to Your Award Proposal & Award Policies & Procedures Guide (PAPPG) NSF Public Access Repository Who to Contact With Questions Facilities and Infrastructure Updates on NSF Priorities Our Directorates & Offices Biological Sciences (BIO) Computer & Information Science & Engineering (CISE) Integrative Activities (OIA) International Science & Engineering (OISE) Mathematical & Physical Sciences (MPS) Social, Behavioral & Economic Sciences (SBE) Technology, Innovation & Partnerships (TIP) National Center for Science & Engineering Statistics (NCSES) National Science Board (NSB) Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science (SCH) Status: Waiting for new publication Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science (SCH) NSF's implementation of the revised 2 CFR NSF Financial Assistance awards (grants and cooperative agreements) made on or after October 1, 2024, will be subject to the applicable set of award conditions, dated October 1, 2024, available on the NSF website .

These terms and conditions are consistent with the revised guidance specified in the OMB Guidance for Federal Financial Assistance published in the Federal Register on April 22, 2024.

Important information for proposers All proposals must be submitted in accordance with the requirements specified in this funding opportunity and in the NSF Proposal & Award Policies & Procedures Guide (PAPPG) that is in effect for the relevant due date to which the proposal is being submitted. It is the responsibility of the proposer to ensure that the proposal meets these requirements.

Submitting a proposal prior to a specified deadline does not negate this requirement.

Updates to NSF Research Security Policies On July 10, 2025, NSF issued an Important Notice providing updates to the agency's research security policies, including a research security training requirement, Malign Foreign Talent Recruitment Program annual certification requirement, prohibition on Confucius institutes and an updated FFDR reporting and submission timeline.

Supports high-risk, high-reward interdisciplinary research that combines computing, engineering, data science and behavioral and cognitive sciences to tackle biomedical and public health challenges and drive transformative health innovations.

Supports high-risk, high-reward interdisciplinary research that combines computing, engineering, data science and behavioral and cognitive sciences to tackle biomedical and public health challenges and drive transformative health innovations.

The purpose of this interagency program solicitation is to support the development of transformative high-risk, high-reward advances in computer and information science, engineering, mathematics, statistics, behavioral and/or cognitive research to address pressing questions in the biomedical and public health communities.

Transformations hinge on scientific and engineering innovations by interdisciplinary teams that develop novel methods to intuitively and intelligently collect, sense, connect, analyze and interpret data from individuals, devices and systems to enable discovery and optimize health.

Solutions to these complex biomedical or public health problems demand the formation of interdisciplinary teams that are ready to address these issues, while advancing fundamental science and engineering. Updates and announcements General Correspondence email sch-correspondence@nsf. gov sch-correspondence@nsf.

gov sch-correspondence@nsf. gov sch-correspondence@nsf. gov sch-correspondence@nsf.

gov sch-correspondence@nsf. gov sch-correspondence@nsf.

gov February 27, 2025 - Bringing Mathematical and Statistical Foundations to… October 29, 2024 - Smart Health Frontiers: Combating Cancer with Advanced… July 16, 2024 - Smart Health Frontiers: Precision Medicine Through Engineering May 16, 2024 - Information and Intelligent Systems (IIS) Office Hours March 5, 2024 - Smart Health Symposium- Technology to Improve the Lives of… October 5, 2023 - NSF-NIH Smart Health Solicitation Webinar September 25, 2023 - NSF-NIH Smart Health Solicitation Webinar January 21, 2021 - DMS Virtual Office Hours Additional program resources NSF-NIH Smart Health Solicitation Webinar - Sept.

25th, 2023 at 3:00pm (EST) - Webinar Recording NSF-NIH Smart Health Solicitation Webinar - Oct.

5th, 2023 at 3:00pm (EST) - Webinar Recording Awards made through this program Browse projects funded by this program Map of recent awards made through this program Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (CISE/IIS) Division of Computer and Network Systems (CISE/CNS) Division of Computing and Communication Foundations (CISE/CCF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (ENG/CMMI) Directorate for Mathematical and Physical Sciences (MPS) Division of Mathematical Sciences (MPS/DMS) Directorate for Social, Behavioral and Economic Sciences (SBE) Division of Behavioral and Cognitive Sciences (SBE/BCS) Program 25-542 is currently waiting for a new publication.

Share on X (formerly known as Twitter) Our Directorates & Offices Budget, Performance & Financial Reporting

Eligibility Requirements

  • Higher education institutions, nonprofits, small businesses, state/local governments

Frequently Asked Questions

Who can apply for Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science?

Based on current listing details, eligibility includes: Higher education institutions, nonprofits, small businesses, state/local governments Applicants should confirm final requirements in the official notice before submission.

What is the typical funding level for Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science?

Current published award information indicates Varies ($250,000 - $500,000) Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.

When is the deadline for Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science?

The current target date is rolling deadlines or periodic funding windows. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.

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