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AHSC Round 10 NOFA is sponsored by Department of Housing and Community Development. The AHSC Program furthers the purposes of AB 32 (Chapter 488, Statutes of 2006), SB 375 (Chapter 728, Statutes of 2008), and SB 32 (Chapter 249, Statutes of 2016) by investing in Projects that facilitate GHG Reduction by supporting more compact, infill development patterns, encouraging Active Transportation and transit usage, and protecting Agricultural Land from sprawl dev The California Strategic Growth Council (SGC) and the California Department of Housing and Community Development (Department) are pleased to announce the release of this Notice of Funding Availability (NOFA) with approximately $650 million in funds for the Affordable Housing and Sustainable Communities (AHSC) Program (AHSC Program or Program). The AHSC Program provides grants and loans to eligible Applicants to benefit Disadvantaged Communities, Low-Income Communities, and Low-Income Households throughout California through increasing accessibility of affordable housing, employment centers, and Key Destinations via low-carbon transportation. These investments result in fewer vehicle miles traveled (VMT) through shortened or reduced vehicle trip length or mode shift from single occupancy vehicle use to transit, bicycling, or walking. Eligible Projects must fall into one of the following three eligible Project Area Types: 1. Transit Oriented Development (TOD) Project Areas2. Integrated Connectivity Project (ICP) Areas3. Rural Innovation Project Areas (RIPA) Keywords: Disadvantaged Communities, Low-Income Households, Transit Oriented Development (TOD) Project Areas, Integrated Connectivity Project (ICP) Areas, Rural Innovation Project Areas (RIPA), Affordable Housing Development (AHD) loan, Housing Related Infrastructure (HRI) grant, Sustainable Transportation Infrastructure (STI) grant, Programs (PGM) (or PGM Costs) grant, AHD homeownership grant.

Targeted Genome Editor Delivery (TARGETED) Challenge is sponsored by Department of Health and Human Services - National Institutes of Health. Subject of the Challenge: Recent advancements in the genome editing technology field have enabled scientists to manipulate genomic sequences rapidly and efficiently. Despite revolutionary progress in this area, several challenges remain. Existing gene editing technologies like CRISPR-cas9, base editors and prime editors have great potential, but existing delivery technologies are not able to deliver gene editing technologies to many target tissues and cell types in sufficient quantities, which hinders clinical applications. While some cell types, like hepatocytes in the liver, have many delivery technologies capable of delivering genome editors, there are many other organs and cell types that are harder to reach. The Targeted Genome Editor Delivery (TARGETED) Challenge is a $6,000,000 challenge to improve the current state of in vivo delivery technologies for genome editors in two Target Areas: 1. Programmable Delivery System for Gene Editing, and 2. Crossing the Blood-Brain Barrier. The National Institutes of Health (NIH), through the Common Fund’s Somatic Cell Genome Editing (SCGE) program, is seeking Participants with ideas or early-stage solutions to join the Challenge with the chance to win up to $1,000,000 and have their solution independently tested and validated in large animal models through NIH-supported independent evaluation relevant to preclinical assessments of investigational products. The Challenge is a three-phase competition. In Phase 1, Participants will be asked to submit a proposal describing their proposed solution and how it will address the requirements for one of the Target Areas. Participants may submit proposed solutions to both Target Areas but must do so with separate proposals that independently address each Target Area’s requirements. Up to ten proposals that are judged to best meet the requirements will each be awarded up to $75,000. Additional prizes of $50,000 may be awarded to additional meritorious solutions on the basis of the Ju

The Foundations for Digital Twins as Catalyzers of Biomedical Technological Innovation (FDT-BioTech) program is a tri-agency initiative by NSF, NIH, and FDA supporting inherently interdisciplinary research that underpins the mathematical and engineering foundations behind the development and use of digital twins and synthetic data in biomedical and healthcare applications. The program funds advances in mathematics, statistics, computational sciences, and engineering required to develop responsive digital twin models incorporating artificial intelligence capabilities. Research areas include in silico models for medical device evaluation, synthetic human generation, and emerging challenges in biomedical technology development and assessment. Awards are up to $1,000,000 for collaborative projects from multiple organizations over 3 years, with the program issuing 6 to 10 awards per cycle. The next deadline is May 4, 2026, with annual cycles on the first Monday of May thereafter. This program specifically targets the foundational computational methods that make biomedical digital twins possible rather than application-specific implementations.