DOE Grants

Unlocking New Levels of Output and Capacity for Key Subsurface Resources SBIR/STTR (UNLOCK SBIR/STTR) is sponsored by U.S. Department of Energy (DOE), Advanced Research Projects Agency Energy (ARPA-E). This program addresses persistent geological and technical obstacles impeding efficient recovery from diverse subsurface resources (oil, natural gas, geothermal, mineral systems) by supporting efforts to develop and field-validate integrated stimulation and enhanced recovery app…

FY26 Phase I Genesis Mission SBIR/STTR Opportunity is sponsored by U.S. Department of Energy (DOE) Office of Technology Commercialization (OTC). This opportunity supports small businesses in developing breakthrough technologies that advance the U.S. Department of Energy's Genesis Mission. It includes the topic area 'Scaling the Biotechnology Revolution' which may be relevant to biotech countermeasure diagnostics.

Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs – Phase I (Fall Release) is sponsored by U.S. Department of Energy (DOE Office of Technology Commercialization). This core federal program offers non-dilutive funding to small businesses to advance R&D on mission-aligned energy technologies. Relevant subtopics routinely feature industrial energy efficiency, advanced manufacturing power electronics, industrial decarbonization, power quality management, and harmonic mitigation technologies for commercial manufacturing applications.

Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase I Topics - Fall 2026 is sponsored by U.S. Department of Energy (DOE) Office of Technology Commercialization (OTC). This program provides funding to small businesses for innovative research and development (R&D) that strengthens U.S. energy and national security. The Fall 2026 topics span grid innovation, cybersecurity, AI, and other areas with strong commercial potential, which may include transformer supply chain forecasting and analytics. Companies that receive awards keep the rights to any technology developed and are encouraged to commercialize it.

Small Business Innovation Research (SBIR) Program (DOE CESER) is sponsored by Department of Energy (DOE) Office of Cybersecurity, Energy Security, and Emergency Response (CESER). This program supports mission-aligned projects and measurable outcomes for small businesses developing innovative technologies with strong commercial potential in areas relevant to cybersecurity, energy security, and emergency response.

Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase I (Fall 2026) is sponsored by Department of Energy (DOE). This funding opportunity from the DOE supports small businesses in developing innovative technologies with commercial potential across various research topics, including cybersecurity, AI, and software development. Phase I awards typically cap at $300,000 for feasibility studies.

Fall 2026 Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase I Topics is sponsored by U.S. Department of Energy (DOE) Office of Technology Commercialization (OTC). This opportunity supports American small businesses developing innovative technologies with strong commercial potential in areas like grid innovation, nuclear detonation detection, and cybersecurity. Phase I is the entry point to demonstrate technical feasibility.

Small Business Innovation Research and Small Business Technology Transfer Programs (SBIR/STTR) is sponsored by U.S. Department of Energy (DOE). The DOE's SBIR/STTR programs provide federal funding to small businesses focused on energy and national security technologies. The programs prioritize projects demonstrating both technical merit and commercial viability, aiming to accelerate innovation from research to market.

Fall 2026 Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase I Topics is sponsored by Department of Energy (DOE). The DOE's Fall 2026 SBIR/STTR Phase I funding opportunity supports American small businesses in developing innovative technologies with strong commercial potential across a wide range of DOE's priority technology areas. Topics span energy production, energy use, fundamental energy sciences, environmental management, and defense nuclear nonproliferation. This release is managed by DOE's Office of Technology Commercialization (OTC) and emphasizes streamlining management and delivery.

FY26 Fall Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase I Topics is sponsored by U.S. Department of Energy (DOE). The DOE Fall 2026 SBIR/STTR Phase I Topics are open, offering over $200 million in funding across 25 topics in a wide range of DOE's priority technology areas including grid innovation, nuclear detonation detection, cybersecurity, AI and data analytics, software development, and modeling and simulation. This is the entry point for companies to submit a pitch for a Phase I award.

Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase I Topics is sponsored by U.S. Department of Energy (DOE) Office of Technology Commercialization. The program supports for-profit small businesses developing high-risk, innovative technologies with strong commercial potential. Fall topic areas include advanced critical-mineral extraction, processing, and recycling, as well as battery and dual-use technologies.

The Genesis Mission: Transforming Science and Energy with AI is sponsored by U.S. Department of Energy (DOE) Office of Science (SC). The Genesis Mission aims to accelerate discovery and strengthen U. S. leadership in science, medicine, and technology by leveraging artificial intelligence, supercomputing, scientific data, and DOE's world-class research infrastructure.

The Genesis Mission: Transforming Science and Energy with AI is sponsored by U.S. Department of Energy (DOE), Office of Science (SC). This opportunity supports technologies that advance American leadership in artificial intelligence (AI) in alignment with DOE's Genesis Mission. It is offered through DOE's Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs.

The Department of Energy Genesis Mission is a presidential executive order establishing a national effort to accelerate AI-driven scientific discovery. Led by the Secretary of Energy, the Mission creates the American Science and Security Platform, integrating DOE national laboratory supercomputers, secure cloud-based AI environments, and federally curated scientific datasets to train foundation models and develop AI agents for automated research. The initiative targets at least 20 national science and technology challenges spanning advanced manufacturing, critical materials, nuclear energy, quantum information science, and semiconductors. The Mission facilitates interagency coordination, public-private partnerships through cooperative research agreements, and competitive fellowship programs for researchers at national laboratories. Annual reporting to the President tracks platform capabilities, research outcomes, and technology commercialization progress across participating federal agencies and external partners.

Transforming Science and Energy with AI is sponsored by Department of Energy (DOE) Office of Science (SC). This program seeks applications from interdisciplinary teams to accelerate scientific discovery and research and development (R&D) workflows using novel artificial intelligence (AI) models and frameworks. While broad, research in graph learning and spectral network diffusion dynamics could contribute to AI advancements in scientific domains relevant to energy and other critical areas.

Continuation of Solicitation for the Office of Science Financial Assistance Program (Open Call) is sponsored by Department of Energy (DOE) Office of Science, Biological and Environmental Research (BER). Starting in FY2026 (October 1st, 2025), BER will request research proposals through this "Open Call" for most of its program areas. The research areas of interest for the corresponding fiscal year will be described within the BER section of the Open Call.

The Genesis Mission: Transforming Science and Energy with AI (DE-FOA-0003612) is sponsored by U.S. Department of Energy (DOE) Office of Science, Office of Critical Minerals and Energy Innovation, Office of Environmental Management, Office of Nuclear Energy, Office of Electricity, and Hydrocarbons and Geothermal Office. This opportunity supports mission-aligned projects and measurable outcomes.

The Genesis Mission: Transforming Science and Energy with AI is sponsored by U.S. Department of Energy (DOE), Office of Science, Basic Energy Sciences (BES). This program focuses on integrating artificial intelligence (AI) to transform science and energy research. While specific to AI, it aligns with BES's mission to advance fundamental science.

The Genesis Mission: Transforming Science and Energy with AI (DE-FOA-0003612) is sponsored by U.S. Department of Energy (DOE) Office of Science. This funding opportunity supports research teams using artificial intelligence (AI) to tackle complex national scientific and energy challenges, including biotechnology, advanced manufacturing, critical materials, quantum information science, and nuclear energy. It is part of the agency's broader Genesis Mission initiative, bringing together interdisciplinary teams from national laboratories, universities, and the private sector to accelerate scientific discovery.

This request for applications, issued as DE-FOA-0003612 by the DOE Office of Science, is the main competitive vehicle of the Genesis Mission, the Department of Energy's push to use artificial intelligence to accelerate scientific discovery across its mission space. It anticipates 293.76 million US dollars in awards against twenty-one named national challenge areas, including reenvisioning advanced manufacturing and industrial productivity, scaling the biotechnology revolution, securing America's critical minerals supply, delivering nuclear energy that is faster, safer and cheaper, achieving AI-driven autonomous laboratories and designing materials with predictable functionality, alongside further topics spanning quantum information science, semiconductors, discovery science and energy systems. The two-phase design funds a nine-month Phase I at 500,000 to 750,000 dollars to establish feasibility, then a three-year Phase II at 6 to 15 million dollars to build and deploy. The mandatory team composition is the defining feature: Phase I teams must include at least two of DOE or NNSA national laboratories, industry, or higher education and non-profit organisations, and Phase II teams must include at least one national laboratory partner and at least one industry partner, with higher education participation strongly encouraged. That requirement makes this a partnership instrument rather than a single-investigator grant, and it routes access to DOE's data, computing facilities and experimental infrastructure through the laboratory partner. Phase I applications and Phase II letters of intent were due 28 April 2026; full Phase II applications are due 17 December 2026.

Genesis Mission: Transforming Science and Energy with AI is sponsored by U.S. Department of Energy (DOE) Office of Science (SC). Supports interdisciplinary teams addressing national science and technology challenges to accelerate scientific discovery and research and development (R&D) workflows using novel artificial intelligence (AI) models and frameworks, with a focus on advancing DOE's mission in areas…

DE-FOA-0003612: The Genesis Mission: Transforming Science and Energy with AI is sponsored by U.S. Department of Energy (DOE) Office of Science, Office of Fusion Energy Sciences (FES). FES is interested in applications for preliminary design studies exploring the creation of volumetric neutron sources (VNS) based on the next generation of fusion concepts, with the potential for significant cost share through public-private partnerships.

The Genesis Mission: Transforming Science and Energy with AI, DE-FOA-0003612 is sponsored by U.S. DOE Office of Science (SC), Basic Energy Sciences (BES). This funding opportunity focuses on new grant applications from universities and other research institutions for basic energy sciences, with an emphasis on transforming science and energy with AI.

The Genesis Mission: Transforming Science and Energy with AI is sponsored by U.S. Department of Energy (DOE) Office of Science, Biological and Environmental Research (BER). This program supports AI-enhanced climate and earth system modeling and technologies in four areas, including 'Scaling the Biotechnology Revolution.' Proposals advancing biotechnology, especially those with strong commercial potential and alignment with DOE's mission, are encouraged.

Grants for Energy Improvements in Rural or Remote Areas (ERA) is sponsored by U.S. Department of Energy (DOE Office of Clean Energy Demonstrations). Provides financial assistance to small businesses and community organizations to improve energy resilience, safety, and reliability, which can encompass local critical mineral processing, microgrid integration, and circular-economy infrastructure deployed in rural and remote reg…

Artificial Intelligence Technology in Career and Technical Education Pathways is sponsored by New Jersey Department of Education (NJDOE). This grant aims to expand access to high-quality AI applications within Career and Technical Education (CTE) programs in New Jersey. It supports districts in developing innovative, project-based learning experiences, creating real-world industry-connected opportunities, building partnerships with business and industry, and providing professional learning for CTE educators. Grantees are expected to provide AI-integrated project-based learning modules and curriculum resources.

Science Undergraduate Laboratory Internships (SULI) program and Community College Internships (CCI) program is sponsored by U.S. Department of Energy (DOE) Isotope Program (DOE IP). These internship programs offer mentored research opportunities in science and engineering fields supporting the DOE mission, including nuclear energy and technology, for undergraduate and community college students.

PROSPECT Program: Providing Opportunities for Specialized Education in Critical Technologies is sponsored by U.S. Department of Energy (DOE) Office of Critical Minerals and Energy Innovation (CMEI). Establishes collaborative approaches that strengthen educational and technological pathways across the entire critical minerals and materials value chain—from mineral resource development and extraction through processing, manufacturing, and circular recycling supply chain activities.

FY 2027 Continuation of Solicitation for the Office of Science Financial Assistance Program (DE-FOA-0003665) is sponsored by U.S. Department of Energy (DOE) Office of Science. This program supports fundamental research in various scientific areas, potentially including aspects of fluid dynamics, turbulence, and aerodynamics relevant to energy applications. While not explicitly focused solely on fluid dynamics, the broad scope of the Office of Science's research can encompass related topics. Applications may be submitted any time during the period the NOFO is open.

Office of Science Financial Assistance Program is sponsored by U.S. Department of Energy (DOE) Office of Science. The DOE Office of Science issues annual solicitations for basic and applied research proposals from colleges and universities in various scientific areas, including advanced scientific computing, basic energy sciences, biological and environmental research, fusion energy, high energy, and nuclear physics.

FY 2027 Continuation of Solicitation for the Office of Science Financial Assistance Program is sponsored by U.S. Department of Energy (DOE) Office of Science. This is a broad, open solicitation for research proposals in topic areas spanning the Office of Science program areas. While not explicitly fluid mechanics, the Office of Science supports fundamental research, and proposals related to fluid mechanics, especially in energy and environmental contexts, could be considered.

Open Call for Scientific Research is sponsored by DOE Office of Science. This annual funding opportunity supports fundamental scientific research across various disciplines, including those relevant to computational design, AI, and data science, that are not covered by more specific solicitations. It aims to advance the frontiers of scientific knowledge and lay the foundation for future technologies and innovation.

Computer Science Program is sponsored by U.S. Department of Energy (DOE) Office of Science (SC). The ASCR Computer Science research program supports long-term, basic research that enables computing and networking at extreme scales. Key activities include foundational research in developing adaptive, portable, high-performance scientific software, including testing, validation, and verification; and techniques for integrating and scaling scientific AI.

Continuations of Solicitation for the Office of Science Financial Assistance Program (DE-FOA-0003600) is sponsored by U.S. Department of Energy (DOE) - Office of Science (SC). This is an open solicitation from the DOE Office of Science that accepts proposals year-round in various research topic areas spanning the Office of Science program areas.

The FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program is an open annual grant from the U.S. Department of Energy (DOE) Office of Science that funds research across its core program areas, including Advanced Scientific Computing Research, Basic Energy Sciences, Biological and Environmental Research, Fusion Energy Sciences, High Energy Physics, Nuclear Physics, and Isotope R&D and Production. Any research within SC's Congressionally authorized mission may be proposed under this solicitation, which remains open throughout the fiscal year. Eligible applicants include colleges and universities, non-profit and for-profit research organizations, DOE national laboratories, small businesses, and other federal research organizations. Anticipated awards range from $750,000 to $3,000,000 per year; the solicitation closes September 30, 2026.

Continuations of Solicitation for the Office of Science Financial Assistance Program is sponsored by U.S. Department of Energy (DOE) Office of Science. This program issues announcements to solicit research proposals from various entities, including colleges and universities, non-profit and for-profit research organizations, DOE's national laboratories, small businesses, and other federal research organizations. Research topics must fall within the programmatic priorities of DOE's Office of Science.

Continuations of Solicitation for the Office of Science Financial Assistance Program (DE-FOA-0003600) is sponsored by U.S. Department of Energy (DOE), Office of Science. This is an open solicitation from the DOE Office of Science that accepts proposals year-round in various research topic areas spanning the Office of Science program areas.

Basic Research to Advance the Frontiers of Science (Annual Funding Opportunity) is sponsored by U.S. Department of Energy (DOE). This annual funding opportunity from the DOE Office of Science supports basic research across various scientific computing research areas. While not explicitly focused on 6G wireless, it could support fundamental research in advanced networking and optical technologies relevant to 6G, especially given DOE's interest in leveraging advanced wireless for scientific applications.

ORNL Manufacturing Demonstration Facility (MDF) Technical Collaboration Program is sponsored by U.S. Department of Energy (DOE), Office of Energy Efficiency and Renewable Energy (EERE), Advanced Materials and Manufacturing Technologies Office. This program engages industry partners in short-term, collaborative projects with Oak Ridge National Laboratory (ORNL) staff to accelerate the development and deployment of new manufacturing technologies, materials, or processes for the benefit of U.

University Nuclear Leadership Program – Scholarship and Fellowship Support is sponsored by U.S. Department of Energy (DOE) Idaho Field Office. This program awards cooperative agreements to accredited U.S. two- and four-year colleges and universities to administer scholarship and fellowship funding. It aims to attract qualified nuclear science and engineering students to nuclear energy professions by providing financial support for undergraduate and graduate programs in related disciplines such as nuclear engineering, mechanical engineering, electrical engineering, chemistry, and health physics.