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The National Cardiovascular Health Program is sponsored by Department of Health And Human Services. This program supports extensive scientific evidence, links nonmedical factors, including systemic racism and the lack of economic opportunities, with poor health outcomes and increased mortality rates, all of which are preventable. Factors such as poverty, inadequate housing, poor health care, and other debilitating social conditions, commonly referred to as social determinants of health, contribute to long-standing disparities and health inequities. These social conditions contribute to the increased prevalence of cardiovascular disease (CVD) in the US population. CVD is the leading cause of death in the US; stroke is the 5th leading cause. In 2020, about 1 in 5 adults who died from CVD were younger than 65 years old. It is estimated that 1 in 9 health care dollars are spent on CVD.
CVD mortality rates declined for several decades due to both clinical and public health interventions, but recently declining death rates from both heart disease and stroke have stalled. One reason is that hypertension, the primary risk factor for CVD, is very common (1 in 2 US adults has hypertension) but control is not. Only 1 in 4 adults with hypertension (26.1%) has it under control. Gains have been made in treating high cholesterol, another primary risk factor for CVD. Overall, the age-adjusted prevalence of high cholesterol decreased from 21% to 10% from 1988–1994 to 2017–2018. This improvement is due in part to individuals’ healthy behaviors such as eating a healthy diet, losing weight, being physically active, and medication adherence, along with clinical contributions from appropriate prescribing and intensification of medication. Additional public health and health system interventions aimed at preventing, detecting, and controlling elevated cholesterol and blood pressure can help to further decrease CVD mortality. This listing is currently active. Program number: 93.426. Last updated on 2026-01-12.
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Or search similar grants →According to the current listing, eligibility includes: State Governments or their Bona Fide Agents (includes the District of Columbia) are eligible Eligible applicant types include: U.S. State Government (including the District of Columbia). Confirm the full requirements in the official notice before applying.
The current listing shows recent federal obligations suggest $75,993,412 (2026). Verify award ceilings, matching requirements, and allowable costs in the official notice.
Yes — The National Cardiovascular Health Program is offered by Department of Health And Human Services and this listing comes from SAM.gov, an official U.S. federal source. Federal applications generally require registrations (for example SAM.gov or an agency submission portal), so allow extra lead time.
This opportunity targets applicants in District of Columbia. If your organization operates elsewhere, check the official notice for location requirements.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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Research Infrastructure Programs - Construction is sponsored by Department of Health And Human Services. The Office of Research Infrastructure Programs (ORIP), within the Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI) in the NIH Office of the Director, supports extramural biomedical research by strengthening the infrastructure that enables scientific discovery. ORIP advances human health by fostering the development of critical research models, biomaterials, and technologies; expanding access to state-of-the-art instrumentation and facilities; supporting education and training programs; and assisting small businesses in translating innovative technologies. Through its two divisions, the Division of Comparative Medicine (DCM) and the Division of Construction and Instruments (DCI), ORIP plays a critical role in accelerating biomedical research nationwide. DCM develops and sustains essential research models and biological resources, manages the infrastructure required for their use and distribution, and provides training to ensure investigators have reliable access to high-quality models and facilities. DCI supports shared, cost-effective access to advanced scientific instrumentation, modernizing research facilities, and providing critical equipment that enables transformative biomedical discoveries. Together, DCM and DCI strengthen U.S. competitiveness and ensure the biomedical research community has the infrastructure necessary to address emerging health challenges, prevent disease, promote health, and advance foundational science. This listing is currently active. Program number: 93.CN1. Last updated on 2026-01-28.
Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is sponsored by Department of Health And Human Services. To provide extramural research support for the Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative’s aim of revolutionizing our understanding of the brain and its function in unprecedented detail. The NIH BRAIN Initiative’s focus is foundational development of new technologies and tools to map, monitor, and modulate brain circuits in model systems and humans – toward the ultimate goal of treating and curing human brain disorders. BRAIN Initiative research adheres to open, and ethical science. BRAIN-supported research areas include comprehensive cataloguing, mapping, accessing and characterization of brain cell types ; probing neural circuits that interact and produce behavior, cognition, and emotion; developing and employing new technologies to monitor function and connectivity of synapses, circuits, and whole brains; partnering with human research participants, including utilizing neurotechnologies in first-in-human clinical studies, to study the human brain in the context of brain injury and brain disorders; and establishing data-sharing platforms and computational models that help decode brain processes and functions. Within these scientific focus areas, the Initiative supports research project grants, cooperative agreements, workforce development awards and Small Business Innovation Research awards. Research supported by the Initiative has a strong commitment to broad dissemination of newly developed technologies, and to considering neuroethical issues related to studying the human brain and the neuroscience advances that follow from this research. New frontiers for BRAIN research will adhere to, and build on, what has been learned to date and adapt to the rapidly changing scientific landscape and neuroscience ecosystem. This listing is currently active. Program number: 93.BZ1. Last updated on 2026-01-28.
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