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Agentic AI-EnableD CardioVascular CAre TransfOrmation (ADVOCATE) is sponsored by Advanced Research Projects Agency for Health (ARPA-H). A competitive Innovative Solutions Opening (ISO) seeking teams to develop trusted, autonomous clinical AI agents for continuous cardiovascular patient care and monitoring. Official opportunity description and requirements excerpt: An official website of the United States government The .gov means it’s official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. Open Funding Opportunities Submission Resources and FAQs Commercialization Services ARPANET-H Innovation Network Other Transaction Community What is a Program Manager? Program Manager Application Agentic AI-Enabled Cardiovascular Care Transformation What if an FDA-authorized clinical agentic AI could provide safe and effective cardiovascular care to every American? Over 200,000 Americans die each year from preventable impacts of cardiovascular disease (CVD), the leading cause of death in the U.S. Despite spending almost half a trillion dollars on heart disease alone, the US experiences much worse outcomes than many other similar nations. Treatments for managing heart health with diet, exercise, and affordable medications are simple, inexpensive, and effective. Yet nearly half of American counties lack a cardiologist, meaning that many patients across the country are missing out on life-saving care and interventions. Clinical artificial intelligence (AI) agents could help fill this gap, but we don’t currently have a clear way to ensure they consistently operate safely and effectively at scale in real-world settings. The Agentic AI-EnableD CardioVascular CAre TransfOrmation (ADVOCATE) program aims to transform advanced cardiovascular disease management with an agentic AI system that can provide 24/7 holistic clinical care. ADVOCATE will support the development of clinical AI agents that can be trusted to autonomously adjust changes in appointments, medications, diet, and exercise. In parallel, ADVOCATE will support the development of a supervisory AI "overseer” to monitor clinical AI agents after they have been deployed in clinical practice to ensure their continued safety and efficacy. ADVOCATE's transformative goal is to create a first-of-its-kind, reliable, FDA-authorized clinical agentic AI system that serves around the clock as a new, digital member of the clinical care team. Together, these efforts will enable an integrated, holistic cardiovascular care platform to provide real-time guidance that patients and care teams can act on. The program will partner with health systems to successfully deploy the technology across diverse care environments—from major health systems to rural clinics and community settings. Harness the power of American innovation to quickly develop agentic AI that is safe, transparent, and effective in healthcare settings. Unleash the best technical experts across sectors to tackle a leading cause of death in the U.S. and accelerate pathways for regulatory and reimbursement approvals. Build Application snapshot: target deadline February 27, 2026; published funding information $1,000,000 - $9,000,000; eligibility guidance Nonprofits, universities, small businesses, and for-profit industry teams. Use the official notice and source links for final requirements, attachment checklists, allowable costs, and submission instructions before applying.
Health Equity Grants for Addressing Social Determinants of Health is sponsored by The DAISY Foundation. Provides funding for nurse-led research and evidence-based projects that address social determinants of health and improve equity in community outcomes. Official opportunity description and requirements excerpt: Health Equity Grants for Addressing SDoH | DAISY Foundation Health Equity Grants for Addressing SDoH Social determinants of health (SDoH) - the conditions in the places where people live, learn, work, and play - affect a wide range of health risks and outcomes. As stated by Healthy People 2020, "Our health is ... determined in part by access to social and economic opportunities; the resources and support available in our homes, neighborhoods, and communities; the quality of our schooling; the safety of our workplaces; the cleanliness of our water, food, and air; and the nature of our social interactions and relationships. The conditions in which we live explain in part why some Americans are healthier than others and why Americans more generally are not as healthy as they could be." Given the trusting relationships nurses forge with patients and families, nurses are positioned to influence treatment and provide advice that may mitigate SDoH, leading to improved health outcomes. ( https://www.healthypeople.gov/2020/topics-objectives/topic/social-determinants-of-health ). As The DAISY Foundation delves into how it can serve the advancement of equitable delivery of healthcare, our attention is drawn to our aging population and the need to improve care and promote healthy aging of older adults , which we now include as part of our Health Equity Grants. - General Guidelines and Requirements - If Your Grant is Funded- Required Reports - Download a Grants Flyer to Share with Staff The DAISY Foundation is eager to support the delivery of patient- and family-centered care of disadvantaged populations by funding nursing research and evidence-based practice (EBP) projects designed to address social determinants of health aimed at improving health outcomes. The DAISY Foundation expects the principal investigators or EBP project leaders to design projects that support the needs of their local community, which are aligned with their organization’s Community Relations Office’s priorities. Dissemination of the results of this scholarly work, both internal and external to the organization, will expand the evidence needed to inform interventions that improve health and reduce health disparities. General Guidelines and Requirements for Research Grants and EBPs Target populations for the DAISY-funded studies or projects are those populations with a wide range of health risks based on one or more of the five social determinants of health categories outlined in the figure above. For example, the project population may include those who are disadvantaged because of economic instability; exposure to risk based in their neighborhood or living conditions; low health literacy or poor access to health care; racial disparities or social isolation; or low levels Application snapshot: target deadline March 1, 2026; published funding information $10,000; eligibility guidance Nurses and nursing teams working within clinical or community health settings. Use the official notice and source links for final requirements, attachment checklists, allowable costs, and submission instructions before applying.
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