Career Catalyst Research Grants (CCR) is sponsored by Susan G. Komen. Fosters promising breast cancer researchers in the early stages of their faculty careers by providing support for up to three years of protected time for research career development under the guidance of a Mentor Committee.

Career Catalyst Research Grants (CCR) | Research Funding Komen for the Cure, Susan G. Career Catalyst Research Grants (CCR) For more than a decade, Susan G. Komen Career Catalyst Research (CCR) Grants have fostered promising breast cancer researchers who are in the early stages of their faculty careers by providing support for up to three years of “protected time” for research career development under the guidance of a Mentor Committee.

We seek to support those who will emerge as the next key leaders in the fight against breast cancer. Research projects must be hypothesis-driven, breast cancer-focused studies. They may be considered basic, translational, clinical and/or population science in nature and should align with Komen’s research goals and priorities and mission to save lives from breast cancer.

CCR Limited Submission Nomination Process: Institutions must respond to missiongrantsadmin@komen. org by June 5, 2025, to indicate that they are opting-in to the institutional nomination process. This is a limited submission opportunity: each institution may submit one nominee to apply for this funding.

Applicant/PI cannot self-nominate. The Institution’s Office of Sponsored Programs, Grants Office, or equivalent must select the nominee to apply for this funding.

Duke Internal Deadline: June 26, 2025 Letter of Intent Due: July 24, 2025 , by 1pm, ET Applicant/PI must currently hold a full-time faculty appointment or have a formal offer letter from the Institution that confirms position and start date by the Application due date (October 2, 2025) .

Applicants/PIs must not have held any faculty appointment, including non-tenure and tenure track appointments combined, for more than a total of 6 years by the Application due date (October 2, 2025) . CCR Grant Terms: Applicant/Primary Investigator (PI) may request funding of up to $150,000 per year (combined direct and indirect costs) for up to three years ($450,000).

Owing to the sponsor's restriction on the number of applications that may be submitted from Duke, anyone wishing to pursue nomination should submit the following materials: Required Submission Materials: Proposal (2-page) including the following components (all within the two-page limit): Title: The title should be lay-friendly and accurately describe the focus of the proposal.

It should be no more than 81 characters in length (including spaces) and should not include abbreviations or all capital letters. Research Plan: Research projects must be hypothesis-driven, breast cancer-focused studies. They may be considered basic, translational, clinical, data science and/or population science in nature and should align with Komen's research priorities and mission to save lives from breast cancer.

The Research Plan must demonstrate consideration to the entire 5-year grant term expected of this grant mechanism, including detailed information on the near-term specific aims and research goals and how the mentored phase (Phase 1)will lead to the independent phase (Phase 2) of research.

The Applicant/PI must propose a Research Plan that includes a clear and concise statement of the research question, hypothesis(es) and specific aims of the Research Project.

Impact and Innovation : Briefly summarize how, if successful, the proposal and specific aims will increase our understanding of breast cancer and lead to advances in the field and/or breast cancer care, and the project's significance and potential impact to breast cancer patients, including who will/will not benefit from the findings of the research study.

Career Plan : The Applicant/Pl must submit a career development plan encompassing the 5-year grant term that conveys how the Applicant/PI is well positioned to pursue a career in breast cancer research and discusses their potential for making an impact in the breast cancer field. Statement of Applicant/PI and Lead Mentor Eligibility (see attached RFA for details) Applicant/PI and Lead Mentor Biosketch Submission Link: https://app.

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