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Clinical Trials Grants Program (OOPD) is sponsored by FDA Office of Orphan Products Development (OOPD). This program funds clinical trials evaluating efficacy and/or safety for new indications or changes in labeling to address unmet needs in rare diseases or conditions. It encourages innovative and efficient clinical trial methods such as adaptive and seamless trial designs.
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Search similar grants →According to the current listing, eligibility includes: Not explicitly stated, but generally targets institutions and organizations involved in clinical research for rare diseases. University of Maryland Baltimore is likely eligible due to its research focus. Confirm the full requirements in the official notice before applying.
Clinical Trials Grants Program (OOPD) is funded by FDA Office of Orphan Products Development (OOPD). Verify program details on the funder's official page before applying.
This opportunity targets applicants in Maryland. If your organization operates elsewhere, check the official notice for location requirements.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Past winners and funding trends for this program
The Natural History Studies of Orphan Products (R01) grant is a program from the FDA Office of Orphan Products Development (OOPD) that funds research to better understand the progression, presentation, and unmet needs of rare diseases. Because rare diseases lack the extensive clinical knowledge base of common conditions, natural history studies are critical to developing safe and effective medical products. The program supports public and private entities conducting studies to characterize disease course, identify core unmet needs, and establish endpoints for future clinical trials. Grant amounts vary based on study scope and research design.
Orphan Products Grants Program is sponsored by FDA Office of Orphan Products Development (OOPD). This program funds clinical studies of medical products (drugs, biologics, medical foods, or medical devices) used in rare diseases for which no therapy currently exists or for which the proposed product will outperform currently available options.
The BARK program funds dual-use medical products for warfighters and military working dogs — tourniquets, sensors, drug delivery, and CBRN countermeasures. Proposals close June 3, 2026.
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