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Collaborative Awards to Support Microphysiological System Pilot Studies in Type 2 Diabetes Research is a grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) that funds collaborative research pairing microphysiological system (MPS) experts with traditional biology laboratories to advance type 2 diabetes research.
The program supports patient-on-a-chip and clinical-trial-on-a-chip studies using patient samples and human iPSC-derived cells to model metabolic tissue crosstalk, study T2D mechanisms, and test treatment strategies. Eligible applicants include universities, research institutions, private and public higher education institutions, federally recognized Native American tribes, and special district governments.
Awards total $1,000,000, with applications due July 5, 2026.
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Collaborative Awards to Support Microphysiological System Pilot Studies in Diabetes Research - NIDDK Advisory & Coordinating Committees National Diabetes & Digestive & Kidney Diseases Advisory Council Collaborative Awards to Support Microphysiological System Pilot Studies in Diabetes Research Return to Concept Clearances Collaborative Awards to Support Microphysiological System Pilot Studies in Diabetes Research Advances in biomaterials, microfluidics, and tissue engineering have resulted in microphysiological systems (MPSs) that allow for greater control of three-dimensional cell cultures containing multiple cell types and constituting more physiological tissue organization.
The use of patient samples and human induced pluripotent stem cell–derived cells coupled with MPSs will enable patient-on-a-chip or clinical-trial-on-a-chip studies of type 2 diabetes development and treatment that is currently not possible.
The utility of these systems lends themselves to powerful in vitro modeling of metabolic tissue crosstalk, study of basic mechanisms of human type 2 diabetes, and the testing of prevention and treatment strategies. MPSs are especially useful for investigating the heterogeneity of human T2D biology and clinical responses.
However, adoption of such systems as a complementary research tool by traditional basic biology laboratories requires additional MPS expertise and resources. Opportunities exist for NIDDK to incentivize collaborative studies to encourage pairings of engineering and biology labs.
The current initiative will support small pilot studies to conceptualize aspects of T2D biology for modeling with MPSs, to support feasibility studies, and to generate preliminary data. It is anticipated that these pilot awards may pave the way to enhance the success of future R01 submissions and broaden the use of MPSs in human T2D research.
According to the current listing, eligibility includes: Independent school districts, private institutions of higher education, public and state institutions of higher education, public and Indian housing authorities, special district governments, federally recognized Native…. Confirm the full requirements in the official notice before applying.
The current listing shows $1,000,000. Verify award ceilings, matching requirements, and allowable costs in the official notice.
The published deadline was July 5, 2026, which has passed. Check the official notice for any future application windows before investing time in a proposal.
Collaborative Awards to Support Microphysiological System Pilot Studies in Type 2 Diabetes Research is funded by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
NCI Continuing Umbrella of Research Experiences (CURE) Academic Career Excellence (ACE) Award (K32) is a grant from the National Cancer Institute (NCI) that funds early postdoctoral fellows from diverse backgrounds, including underrepresented groups, to pursue research training in cancer-related fields. The K32 award supports fellows within 12 months prior to transitioning into, or within the first two years of, a postdoctoral position. The program, operated through NCI's Center to Reduce Cancer Health Disparities (CRCHD), aims to enhance the pool of qualified diverse cancer researchers. Beginning with the June 12, 2025 due date, the CURE ACE Award is available in both Independent Clinical Trial Required and Independent Clinical Trial Not Allowed versions. Eligible applicants must be U.S. citizens or permanent residents at time of award.
Innovation Grant is a grant from the Delta Dental of Arizona Foundation that funds nonprofit organizations pursuing unique, high-impact projects that improve health and wellness in Arizona communities. This two-year award supports original initiatives with measurable real-world impact, including programs serving underserved and uninsured populations through oral health education, disease prevention, and nutritional access. Projects must demonstrate the potential to make a meaningful difference in the community and stand apart from conventional approaches. Eligible applicants are Arizona-based nonprofit organizations. Awards total $100,000 per recipient over two years. The 2026 application cycle closed October 16, 2025, with recipients notified in late 2025 and funding made available shortly after.