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Digital Health (DH) - Small Business Innovation Research (SBIR) Program is sponsored by National Science Foundation (NSF). The Digital Health topic supports early-stage startups developing innovative technologies to improve physical or mental well-being, increase independence, and enhance healthcare delivery by improving efficiency, reducing costs, or improving outcomes.
This includes technologies applying AI in healthcare, personalized medicine, EHR/EMR, clinical decision support, and smart medical devices.
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Digital Health Grant – Apply Today | NSF SBIR Check recent critical alerts! (Last updated 4/16/2026) NSF will resume the submission of new Project Pitches to the SBIR/STTR programs in the coming weeks. Program Directors will continue to process Project Pitches that were previously received.
Please direct any questions to sbir@nsf. gov . The Neural Analytics Lucid™ M1 transcranial Doppler Ultrasound System is indicated as an adjunct to the standard clinical practices for measuring and displaying cerebral blood flow velocity within the major conducting arteries and veins of the head and neck.
Additionally, the Lucid™ M1 System measures the occurrence of transient emboli signals within the blood stream.
The Digital Health topic aims to support entrepreneurs and startups at the earliest-stages of development of innovative, differentiated and novel technologies that aim to improve physical or mental wellbeing or health, enable or assist individuals to increase or regain independence and quality of life and improve the delivery of healthcare including efficiency, reducing cost or improving outcomes.
Technologies in this portfolio include those applying AI in healthcare or general wellness (medical image analysis, personalized medicine, EHR/EMR, Clinical decision support, Computer aided diagnostics, support or therapy, smart/connected medical devices) as well as technologies that enable or provide assistance to aging or disabled populations and individuals undergoing rehabilitation. DH1.
Assistive, Enabling and Rehabilitative technologies DH2. AI in healthcare and drug discovery DH3. Healthcare Workflow, Economics and Delivery DH4.
Medical Diagnostics and Devices DH5. Physical, Mental and Behavioral Health DH6. Other Digital Health Technologies Application process for Digital Health (DH) funding Eligibility for Digital Health (DH) funding + Your company must be a small business (fewer than 500 employees) located in the United States.
At least 50% of your company’s equity must be owned by U.S. citizens or permanent residents. NSF does not fund companies that are majority-owned by multiple venture capital firms, private equity firms, or hedge funds, to participate in SBIR and STTR. All funded work, including work done by consultants and contractors, needs to take place in the United States.
The project’s principal investigator (tech lead) must be legally employed at least 20 hours a week by the company seeking funding. The principal investigator doesn’t need any advanced degrees. The principal investigator needs to commit to at least one month (173 hours) of work on a funded project per six months of project duration.
Evaluation Criteria: What We Look for When Evaluating Digital Health (DH) proposals + Take our project assessment to see if your work might be a good fit for NSF funding.
'Moxi' the robot that supports nurses Diligent Robotics, a small business funded by the National Science Foundation (NSF), created “Moxi,” a robot that supports clinical staff teams in acute care hospitals by executing logistical tasks so staff can focus on direct human care. To learn more visit: https://diligentrobots. com/ We invest up to $2 million in seed funding and take zero equity.
We’re looking for companies that are transformative, high-risk, have a market pull, and are scaleable.
Key questions and narrative sections extracted from the solicitation.
Project description (10–15 pages addressing innovation, technical approach, and R&D plan)
Commercialization strategy
Scoring criteria used to review proposals for this grant.
Based on current listing details, eligibility includes: Small businesses (fewer than 500 employees) located in the United States, with at least 50% equity owned by U.S. citizens or permanent residents. Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates See official notice (Varies by phase and project) Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
The current target date is April 16, 2026. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.
Federal grant success rates typically range from 10-30%, varying by agency and program. Build a strong proposal with clear objectives, measurable outcomes, and a well-justified budget to improve your chances.
Requirements vary by sponsor, but typically include a project narrative, budget justification, organizational capability statement, and key personnel CVs. Check the official notice for the complete list of required attachments.
Yes — AI tools like Granted can help research funders, draft proposal sections, and check compliance. However, always review and customize AI-generated content to reflect your organization's unique strengths and the specific requirements of the solicitation.
Review timelines vary by funder. Federal agencies typically take 3-6 months from submission to award notification. Foundation grants may be faster, often 1-3 months. Check the program's timeline in the official solicitation for specific dates.
Many federal programs offer multi-year funding or allow competitive renewals. Check the official solicitation for continuation and renewal policies. Non-competing continuation applications are common for multi-year awards.
Past winners and funding trends for this program
Improving Undergraduate STEM Education: Education & Human Resources (IUSE: EHR) Program is sponsored by National Science Foundation (NSF). This program promotes novel, creative, and transformative approaches to generating and using new knowledge about STEM teaching and learning to improve STEM education for undergraduate students. It supports projects that bring recent advances in STEM knowledge into undergraduate education, adapt, improve, and incorporate evidence-based practices, and lay the groundwork for institutional improvement in STEM education. Professional development for instructors to ensure adoption of new and effective pedagogical techniques is a potential topic of interest.
Small Business Innovation Research (SBIR)/Small Business Technology Transfer (STTR) Phase I (NSF 24-579) is sponsored by National Science Foundation (NSF). This program provides non-dilutive funds for use-inspired research and development (R&D) of unproven, leading-edge technology innovations that address societal challenges. Small businesses must first submit a Project Pitch and receive an official invitation to submit a full proposal. The maximum award amount has been increased to $305,000, and the award duration is 6-18 months.
NSF Small Business Innovation Research / Small Business Technology Transfer Phase I Programs is sponsored by National Science Foundation (NSF). These programs provide non-dilutive funds for use-inspired research and development of unproven, leading-edge technology innovations that address societal challenges. NSF funds broadly across scientific and engineering disciplines and does not solicit specific technologies.
Research on Circular Economy, Smart Manufacturing, and Energy-Efficient Microelectronics is sponsored by U.S. Department of Energy (DOE) Advanced Materials & Manufacturing Technologies Office (AMMTO). This funding opportunity supports innovative technology R&D across the manufacturing sector with a focus on circular economy, smart manufacturing, and energy-efficient microelectronics. While the stated deadline for full applications has passed, AMMTO frequently issues similar solicitations, and this highlights a relevant area of interest for the DOE.
NIST Small Business Innovation Research (SBIR) Phase II Program - Quantum Information Science is sponsored by National Institute of Standards and Technology (NIST). This program allocates funding to small businesses for prototyping innovative technologies in areas including quantum information science, artificial intelligence, and semiconductors. These Phase II awards follow successful Phase I feasibility studies.