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Digital Healthcare Solutions (R21/R33) is a grant from the Agency for Healthcare Research and Quality (AHRQ) that funds research on innovative digital tools and health information technology to improve quality and safety at the point of care. The program uses a two-phase structure: R21 awards support feasibility and development work with budgets up to $275,000, while R33 awards support efficacy testing with funding up to $1,000,000.
Not all R21 awardees advance to the R33 phase, and proposals must be designed to account for this contingency. Funded projects have addressed clinical decision support systems, mobile health applications, machine learning tools for laboratory test optimization, remote therapeutic monitoring, and AI-based solutions for maternal health. Clinical trials are optional under this grant mechanism.
The application deadline is August 1, 2026.
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Using Innovative Digital Healthcare Solutions to Improve Quality at the Point of Care (R21/R33 - Clinical Trial Optional) | Digital Healthcare Research Using Innovative Digital Healthcare Solutions to Improve Quality at the Point of Care (R21/R33 - Clinical Trial Optional) Examining the Feasibility and Effectiveness of an mHealth Solution Designed to Enhance Clinical Outcomes Among Patients Attending Physical Therapy for Musculoskeletal Pain This research examines whether remote therapeutic monitoring can improve physical therapy outcomes by increasing patient engagement, adherence to home exercises, and communication with providers, while also assessing its impact on healthcare costs and feasibility for broader implementation.
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Principal Investigator(s) Research Themes and Findings Research Themes and Findings DHR 20th Anniversary Blog Series DHR 20th Anniversary Timeline Milestones and Achievements AHRQ Digital Healthcare Research Publications Database Patient-Generated Health Data I Patient-Reported Outcomes Guide to Integrate Patient-Generated Digital Health Data into Electronic Health Records in Ambulatory Care Settings Clinical Decision Support (CDS) CDS Innovation Collaborative (CDSiC) Resource Library Health IT Survey Compendium Time and Motion Studies Database Implementation Toolsets for E-Prescribing Implementation in Independent Pharmacies Implementation in Physician Offices Children's Electronic Health Record (EHR) Format Archived Tools & Resources Digital Healthcare Research Home Digital Healthcare Research Home Digital Healthcare Research Home
Based on current listing details, eligibility includes: Not all R21 awardees advance to R33, and applications must be designed with that contingency in mind. Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates Up to $275,000 for R21 phase; up to $1,000,000 for R33 phase Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
The current target date is August 1, 2026. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.
Federal grant success rates typically range from 10-30%, varying by agency and program. Build a strong proposal with clear objectives, measurable outcomes, and a well-justified budget to improve your chances.
Requirements vary by sponsor, but typically include a project narrative, budget justification, organizational capability statement, and key personnel CVs. Check the official notice for the complete list of required attachments.
Yes — AI tools like Granted can help research funders, draft proposal sections, and check compliance. However, always review and customize AI-generated content to reflect your organization's unique strengths and the specific requirements of the solicitation.
Review timelines vary by funder. Federal agencies typically take 3-6 months from submission to award notification. Foundation grants may be faster, often 1-3 months. Check the program's timeline in the official solicitation for specific dates.
Many federal programs offer multi-year funding or allow competitive renewals. Check the official solicitation for continuation and renewal policies. Non-competing continuation applications are common for multi-year awards.
Health Services Research Dissertation Program (R36) is a grant from the Agency for Healthcare Research and Quality (AHRQ) that funds doctoral candidates conducting health services research dissertations. Awards of up to $40,000 support the preparation and completion of doctoral dissertations focused on improving healthcare delivery, quality, access, and outcomes. Eligible applicants are public or private nonprofit institutions of higher education applying on behalf of their doctoral candidates. AHRQ has identified special emphasis areas including research to improve treatment and management of menopause symptoms. Applications are accepted through standard NIH submission cycles with the next deadline of May 1, 2026. Note that this opportunity expired in March 2026 under PA-23-196; applicants should check the NIH Guide for any successor announcements.
Examining the Impact of Artificial Intelligence (AI) on Healthcare Safety (R18) is sponsored by U.S. Department of Health and Human Services (HHS) / Agency for Healthcare Research and Quality (AHRQ). This funding opportunity supports research on the impact and safe implementation of artificial intelligence in healthcare to improve patient safety.
Examining the Impact of Artificial Intelligence (AI) on Healthcare Safety (R18) is sponsored by Agency for Healthcare Research and Quality (AHRQ), U.S. Department of Health and Human Services. This Notice of Funding Opportunity (NOFO) intends to support healthcare safety by determining whether and how certain breakthrough uses of AI systems can affect patient safety, and how AI systems can be safely implemented and used.
NCI Continuing Umbrella of Research Experiences (CURE) Academic Career Excellence (ACE) Award (K32) is a grant from the National Cancer Institute (NCI) that funds early postdoctoral fellows from diverse backgrounds, including underrepresented groups, to pursue research training in cancer-related fields. The K32 award supports fellows within 12 months prior to transitioning into, or within the first two years of, a postdoctoral position. The program, operated through NCI's Center to Reduce Cancer Health Disparities (CRCHD), aims to enhance the pool of qualified diverse cancer researchers. Beginning with the June 12, 2025 due date, the CURE ACE Award is available in both Independent Clinical Trial Required and Independent Clinical Trial Not Allowed versions. Eligible applicants must be U.S. citizens or permanent residents at time of award.
AAI Career Awards is a grant from the American Association of Immunologists (AAI) that honors members for outstanding research and career achievement. Through multiple award tracks — including the Lifetime Achievement Award, Distinguished Service Award, Distinguished Fellows program, Public Service Award, and Vanguard Award — AAI recognizes immunologists at every career stage who have made exceptional scientific, institutional, or public-policy contributions. Nominations originate from the AAI Council and designated committees. The program celebrates careers defined by scientific excellence, service to the immunology community, and contributions to public advocacy, minority recruitment in the sciences, and disease research. Deadline is September 10, 2025.