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Page describes DISC5 and CLIN2 programs with a January 30, 2026 deadline — not DISC2 Quest Awards. DISC2 is not mentioned anywhere on this page.
"DISC2: The Quest Awards" is currently closed and not accepting applications.
DISC2: The Quest Awards is sponsored by California Institute for Regenerative Medicine. The Quest Awards program promotes the discovery of promising new stem cell-based technologies that could be translated into broad use and ultimately improve patient care.
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CIRM Grant Applications Now Open: DISC5 and CLIN2 | Stem Cell Research The California Institute for Regenerative Medicine (CIRM) has opened applications for its DISC5 and CLIN2 funding programs, offering major opportunities for UCLA investigators in gene, cell, and regenerative medicine. Applications are due January 30, 2026 at 2pm PST Consult with Experts at the UCLA Health Alpha Clinic on your Applications Drs.
Noah Federman and Laurie Shaker-Irwin lead the CIRM-funded UCLA Alpha Clinic efforts in regenerative medicine, gene, and cell therapy clinical research at UCLA. The Alpha Clinic partners with the CTSI and the BSCRC to assist researchers as they navigate UCLA resources to succeed in the application process for CIRM funding.
Resources include those on the discovery and translational side for developing a lead candidate to advance to further testing. On the clinical research side, resources include, amongst many, clinical protocol development, regulatory and FDA affairs, research coordination, and statistical analysis and data management.
In order to best discuss the expertise and resource needs of investigators for their CIRM grant applications, please complete the CIRM Funding Opportunity Interest Survey and we will follow up with you and/or your designee directly to schedule a meeting.
CLIN2: Support for Regenerative Medicine Clinical Trials CIRM’s CLIN2 program funds Phase 1, 2, and 3 clinical trials , including pivotal trials, for regenerative medicine therapies addressing significant unmet medical needs. The program provides not only financial support but also access to CIRM’s internal experts and external advisors to help teams advance toward marketing approval with strong plans for access and affordability.
CLIN2 creates clinical research opportunities that are otherwise limited within traditional funding pathways. DISC5: Foundational and Exploratory Research Funding The DISC5 program supports innovative, early-stage research led by interdisciplinary investigator teams aiming to overcome fundamental knowledge gaps or bottlenecks in stem cell biology and regenerative medicine.
Projects should aim to advance basic understanding of human stem/progenitor cells use stem cells to uncover disease mechanisms or enable therapeutic/biomarker discovery address key scientific or technical challenges in stem cells gene therapy, or other regenerative approaches improve applicability of regenerative medicine to diverse populations. This grant is up to $2. 5M per award (including indirects) for up to 3-year s.
Teams must include two California-based investigators from different labs. A Course in Stem Cell Medicine: From Scientific Research to Patient Care Workshop: Navigating the INTERACT Meeting and Communicating with the FDA View All News and Highlights
According to the current listing, eligibility includes: California-based non-profit and for-profit organizations; non-California organizations may be eligible if research is conducted in CA. Confirm the full requirements in the official notice before applying.
The current listing shows up to $1,500,000. Verify award ceilings, matching requirements, and allowable costs in the official notice.
The published deadline was June 30, 2026, which has passed. Check the official notice for any future application windows before investing time in a proposal.
DISC2: The Quest Awards is funded by California Institute for Regenerative Medicine. Verify program details on the funder's official page before applying.
This opportunity targets applicants in California. If your organization operates elsewhere, check the official notice for location requirements.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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