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The DOE Genesis Mission is a $320 million initiative launched by executive order on November 24, 2025, directing the Department of Energy and its 17 national laboratories to build a shared AI-powered research platform integrating supercomputers, experimental facilities, AI systems, and massive scientific datasets.
The program funds four pillars: the American Science Cloud (AmSC) for shared computing infrastructure; the Transformational AI Models Consortium (ModCon) with $30 million for collaborative AI model development; 14 projects in robotics, automated laboratories, and autonomous control of large-scale experiments; and foundational AI research awards.
In February 2026, DOE released 26 Science and Technology Challenges signaling priority funding areas, including AI-driven autonomous laboratories that can run experiments without human intervention to accelerate drug discovery, materials development, and energy technology breakthroughs.
The stated goal is to use AI to compress research timelines from decades to months and make American research infrastructure competitive with private-sector AI development. New funding opportunities under the Genesis Mission are being announced on a rolling basis through 2026.
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Or search similar grants →According to the current listing, eligibility includes: National laboratories, U.S. universities, nonprofit research institutions, and companies with relevant capabilities in AI, robotics, laboratory automation, and scientific computing. Collaboration with DOE national labs is strongly encouraged. Some opportunities may require partnership with at least one national laboratory. Confirm the full requirements in the official notice before applying.
The current listing shows $320,000,000 total program investment across four pillars. The Transformational AI Models Consortium (ModCon) received $30,000,000. Fourteen projects funded in robotics, automated laboratories, and autonomous control of large-scale experiments. Individual project award amounts vary by pillar and challenge area. Verify award ceilings, matching requirements, and allowable costs in the official notice.
DOE Genesis Mission: AI for Autonomous Scientific Laboratories and Robotics is funded by U.S. Department of Energy (DOE). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
The FY2026 Department of Defense Multidisciplinary University Research Initiative (MURI) program supports basic research in science and engineering at U.S. institutions of higher education, with emphasis on multidisciplinary research where more than one traditional discipline interacts. The Army, Navy, and Air Force basic research offices are seeking applications across 22 topic areas including artificial intelligence and autonomy, information sensing and processing, and systems manipulation. MURI grants typically provide $1.25 million to $1.5 million per year for three years with option to extend two additional years. Approximately $170 million in total funding is available annually across all topics. The program is administered through the Office of Naval Research (ONR), Army Research Office (ARO), and Air Force Office of Scientific Research (AFOSR).
The NSF Convergence Accelerator is a grant from the National Science Foundation (NSF) that funds multidisciplinary teams working to solve national-scale societal challenges through convergence research and innovation. Launched in 2019 under NSF's Directorate for Technology, Innovation and Partnerships, the program operates in two phases: Phase 1 awards are up to $750,000, with successful teams advancing to larger Phase 2 awards. Eligible applicants include institutions of higher education and nonprofit or for-profit organizations. Track I and Track K focus on specific high-priority topics announced each funding cycle. The next deadline is June 15, 2026. Proposals must comply with updated NSF research security policies effective July 2025.
The AI3 Action Institute is a federal effort to build dedicated AI capacity within Native communities rather than fund a single applied AI project. The awardee establishes and operates an AI resource hub for Native communities, providing technology information, facilitating information sharing and technology deployment across tribal and Native-serving organizations, and conducting stakeholder engagement and coalition building across industry, government and academic sectors. Notably, allowable costs cover short-to-medium-term staff costs including the Institute's director as well as facility setup - a recognition that the binding constraint in this space is institutional infrastructure and staffing, not project ideas. The financial structure is the detail that most shapes strategy: with a $2,500,000 floor, a $3,500,000 ceiling and $3,500,000 in total expected program funding across a three-year period, this is effectively a single-award competition, so applicants should assume they are competing for the entire program rather than for a slot in a cohort. Eligibility is restricted to Native-serving entities - federally recognized Indian tribes, incorporated non-federally or state-recognized tribes, consortia of Indian tribes, Native community-based organizations, Urban Indian Organizations, Alaska Native villages and entities, Native Hawaiian serving agencies, Native Pacific Islander serving agencies, and tribal colleges and universities. That eligibility list is broader than many ACF opportunities, extending to Native Hawaiian and Pacific Islander serving agencies as well as tribal entities. Applicants should expect the strongest proposals to combine an existing convening role in Native technology or education with a realistic plan for standing up durable staff capacity within the grant period, since a hub that dissolves when funding ends would not serve the program's purpose. The deadline is August 27, 2026, and applications are submitted through Grants.gov under opportunity number 362270.
On August 24, 2026, DOE and SBA signed a memorandum of agreement creating the Small Business Investment Company-Energy Initiative, pointing a $58 billion SBA-leveraged investment program at DOE's technology priorities. No application, no NOFO, no deadline. Here is how SBIC capital actually works, why a January 2026 rule change made this possible, and what a company sitting on a DOE Phase II award should do about it.
Read articleThe Hydrocarbons and Geothermal Energy Office's University Training and Research program funds coal, oil and gas, and geothermal R&D at U.S. colleges and universities — but every proposal must include a non-academic partner and must build training modules that outlive the award. The LOI deadline is October 1, 2026, with full applications 15 days later. Here is what that compressed window means and why the workforce framing changes what a competitive proposal looks like.
Read articleThe Energy Department's $65.5 million oil and gas production and delivery NOFO splits across four topic areas with wildly different odds. Topic Area 3 alone carries $28 million for Hydrocarbon Infrastructure Test Sites at roughly $7 million per award over five years — and it requires a defined physical site you already control. Here is how the money is actually allocated.
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