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The DOE Genesis Mission is a $320 million initiative launched by executive order on November 24, 2025, directing the Department of Energy and its 17 national laboratories to build a shared AI-powered research platform integrating supercomputers, experimental facilities, AI systems, and massive scientific datasets.
The program funds four pillars: the American Science Cloud (AmSC) for shared computing infrastructure; the Transformational AI Models Consortium (ModCon) with $30 million for collaborative AI model development; 14 projects in robotics, automated laboratories, and autonomous control of large-scale experiments; and foundational AI research awards.
In February 2026, DOE released 26 Science and Technology Challenges signaling priority funding areas, including AI-driven autonomous laboratories that can run experiments without human intervention to accelerate drug discovery, materials development, and energy technology breakthroughs.
The stated goal is to use AI to compress research timelines from decades to months and make American research infrastructure competitive with private-sector AI development. New funding opportunities under the Genesis Mission are being announced on a rolling basis through 2026.
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Search similar grants →Based on current listing details, eligibility includes: National laboratories, U.S. universities, nonprofit research institutions, and companies with relevant capabilities in AI, robotics, laboratory automation, and scientific computing. Collaboration with DOE national labs is strongly encouraged. Some opportunities may require partnership with at least one national laboratory. Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates $320,000,000 total program investment across four pillars. The Transformational AI Models Consortium (ModCon) received $30,000,000. Fourteen projects funded in robotics, automated laboratories, and autonomous control of large-scale experiments. Individual project award amounts vary by pillar and challenge area. Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
The current target date is rolling deadlines or periodic funding windows. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.
Federal grant success rates typically range from 10-30%, varying by agency and program. Build a strong proposal with clear objectives, measurable outcomes, and a well-justified budget to improve your chances.
Requirements vary by sponsor, but typically include a project narrative, budget justification, organizational capability statement, and key personnel CVs. Check the official notice for the complete list of required attachments.
Yes — AI tools like Granted can help research funders, draft proposal sections, and check compliance. However, always review and customize AI-generated content to reflect your organization's unique strengths and the specific requirements of the solicitation.
Review timelines vary by funder. Federal agencies typically take 3-6 months from submission to award notification. Foundation grants may be faster, often 1-3 months. Check the program's timeline in the official solicitation for specific dates.
Many federal programs offer multi-year funding or allow competitive renewals. Check the official solicitation for continuation and renewal policies. Non-competing continuation applications are common for multi-year awards.
Research on Circular Economy, Smart Manufacturing, and Energy-Efficient Microelectronics is sponsored by U.S. Department of Energy (DOE) Advanced Materials & Manufacturing Technologies Office (AMMTO). This funding opportunity supports innovative technology R&D across the manufacturing sector with a focus on circular economy, smart manufacturing, and energy-efficient microelectronics. While the stated deadline for full applications has passed, AMMTO frequently issues similar solicitations, and this highlights a relevant area of interest for the DOE.
Scientific Discovery through Advanced Computing (SciDAC) Institutes is sponsored by U.S. Department of Energy (DOE) Office of Science, Advanced Scientific Computing Research (ASCR). This program supports scientific discovery through advanced computing. While the specific call details for new applications are not explicitly stated as open with a deadline, the program is ongoing and represents a significant funding opportunity for scientific computing research.
EPAs SmartWay Transport Partnership and National Clean Diesel Campaign (NCDC) are announcing the availability of funding assistance to create finance programs, such as low cost leases or revolving loan programs, to achieve significant reductions in diesel emissions throughout the United States. The SmartWay Clean Diesel Finance Program is soliciting proposals for projects that reduce diesel emissions through the creation of national, tribal, regional, state or local finance program(s). Finance programs include, but are not limited to, those that provide the loan recipient a specific financial incentive (i.e., longer terms or lower rates) to purchase or lease eligible retrofitted vehicles or equipment. The proposed finance program should maximize the total project funds available for financing eligible diesel emission reduction solutions and be sustainable to maintain the program. Funding Opportunity Number: EPA-OAR-OTAQ-09-13. Assistance Listing: 66.039. Funding Instrument: CA. Category: ENV. Award Amount: $2M – $12M per award.
The U. S. Environmental Protection Agency Region 2 is soliciting applications for projects that address the 2010 Reduce, Reuse, Recycle, Rebuy (4Rs) in Schools Program goals from applicants carrying out or desiring to carry out projects that serve EPA Region 2: New York, New Jersey, Puerto Rico, and Virgin Islands. Applicantsare required to be members of, or to join, EPAs WasteWise program in order to apply.See subsection E for more information. Funding Opportunity Number: EPA-R2-RPB-01-2010. Assistance Listing: 66.808. Funding Instrument: CA. Category: ENV. Award Amount: $60K total program funding.
The Healthy Communities Grant Program is seeking projects that: Target resources to benefit communities at risk (environmental justice areas of potential concern, places with high risk from toxic air pollution, urban areas) and sensitive populations (e.g. children, elderly, others at increased risk). Assess, understand, and reduce environmental and human health risks. Increase collaboration through community-based projects. Build institutional and community capacity to understand and solve environment and human health problems. Achieve measurable environmental and human health benefits. Proposed projects must: (1) Be located in and/or directly benefit one or more of the three Target Investment Areas which include: Environmental Justice Areas of Potential Concern, Sensitive Populations, and/or Urban Areas in one or more of the EPA Region I States of Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, and/or Vermont; and (2) Identify how the proposed project will achieve measurable environmental and/or public health results in one or more of the five Target Program Areas which include Asthma, Capacity Building on Environmental and Public Health Issues, Healthy Indoor/Outdoor Environments, Healthy Schools, Urban Natural Resources. Funding Opportunity Number: EPA-R1-HC-2010. Assistance Listing: 66.110. Funding Instrument: CA. Category: ENV. Award Amount: $5K – $35K per award.