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The DOE Genesis Mission is a $320 million initiative launched by executive order on November 24, 2025, directing the Department of Energy and its 17 national laboratories to build a shared AI-powered research platform integrating supercomputers, experimental facilities, AI systems, and massive scientific datasets.
The program funds four pillars: the American Science Cloud (AmSC) for shared computing infrastructure; the Transformational AI Models Consortium (ModCon) with $30 million for collaborative AI model development; 14 projects in robotics, automated laboratories, and autonomous control of large-scale experiments; and foundational AI research awards.
In February 2026, DOE released 26 Science and Technology Challenges signaling priority funding areas, including AI-driven autonomous laboratories that can run experiments without human intervention to accelerate drug discovery, materials development, and energy technology breakthroughs.
The stated goal is to use AI to compress research timelines from decades to months and make American research infrastructure competitive with private-sector AI development. New funding opportunities under the Genesis Mission are being announced on a rolling basis through 2026.
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Search similar grants →Based on current listing details, eligibility includes: National laboratories, U.S. universities, nonprofit research institutions, and companies with relevant capabilities in AI, robotics, laboratory automation, and scientific computing. Collaboration with DOE national labs is strongly encouraged. Some opportunities may require partnership with at least one national laboratory. Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates $320,000,000 total program investment across four pillars. The Transformational AI Models Consortium (ModCon) received $30,000,000. Fourteen projects funded in robotics, automated laboratories, and autonomous control of large-scale experiments. Individual project award amounts vary by pillar and challenge area. Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
The current target date is rolling deadlines or periodic funding windows. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.
Federal grant success rates typically range from 10-30%, varying by agency and program. Build a strong proposal with clear objectives, measurable outcomes, and a well-justified budget to improve your chances.
Requirements vary by sponsor, but typically include a project narrative, budget justification, organizational capability statement, and key personnel CVs. Check the official notice for the complete list of required attachments.
Yes — AI tools like Granted can help research funders, draft proposal sections, and check compliance. However, always review and customize AI-generated content to reflect your organization's unique strengths and the specific requirements of the solicitation.
Review timelines vary by funder. Federal agencies typically take 3-6 months from submission to award notification. Foundation grants may be faster, often 1-3 months. Check the program's timeline in the official solicitation for specific dates.
Many federal programs offer multi-year funding or allow competitive renewals. Check the official solicitation for continuation and renewal policies. Non-competing continuation applications are common for multi-year awards.
This is a Follow-on project to expand an existing partnership to include more grade levels and implement a student summer science program which combines hands-on science education, trail maintenance and habitat enhancement project activities. SUSD will assist BLM in developing and presenting site-specific hands-on, interactive natural and heritage resource educational programs and products for K-12 audiences. Programs will be correlated to California State Educational standards, and shall be developed in collaboration with BLM and partner technical experts to be culturally relevant to the student population and accurately and respectfully interpret local Native American culture. SUSD will utilize the expertise of its Native American Education program and shall work closely with local tribes and BLM to develop programs to meet mutual goals. Programs and products will emphasize Tread Lightly! and Leave No Trace principles and practices in order to foster a new generation of responsible outdoor recreationists and land users. Funding Opportunity Number: CA-NOI-08-0013. Assistance Listing: 15.225. Funding Instrument: CA. Category: ED. Award Amount: $30K – $374K per award.
The Bureau of Land Management, Wyoming State Office, intends to award a cooperative agreement with the Colorado State University to investigate the distribution, abundance, and habitat use of hornyhead chub in the Lower Laramie River Drainage. The anticipated length of the project is a 3 year period. The BLM will consider continued funding for the project upon (a) the recipient showing progress satisfactory to the BLM toward program goals and the determination by the BLM that continuation of the program would be in the best interest of the Government or (b) the availability of funds. The total project period for this award will not exceed 37 months. Funding Opportunity Number: WY-NOI08-9018. Assistance Listing: 15.231. Funding Instrument: CA. Category: NR. Award Amount: Up to $77K per award.