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Florida High Tech Corridor's Small Business Innovation Research and Small Business Technology Transfer Awards is sponsored by Florida High Tech Corridor. This opportunity supports mission-aligned projects and measurable outcomes.
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Florida High Tech Corridor FL FAST: Florida’s First Centralized SBIR/STTR Support System for Entrepreneurs The National Science Foundation's SBIR/STTR Program SBIR/STTR Agency Specific Application Support Programs The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs are highly competitive programs that encourage domestic small businesses to engage in Federal Research/Research and Development (R/R&D) with the potential for commercialization.
Through a competitive awards-based program, SBIR and STTR enable small businesses to explore their technological potential and provide the incentive to profit from its commercialization. More than 7,000 awards totaling $4 billion are distributed annually by 11 participating federal agencies, including the Department of Defense, Department of Energy, National Science Foundation, and NASA.
Companies supported by the SBIR/STTR programs often generate some of the most important breakthroughs each year in the U.S. Additional information about the programs, as well as past and current topics can be found at The Florida High Tech Corridor helps Florida’s small businesses tap into SBIR/STTR awards.
Companies that are successful in securing SBIR/STTR awards and are engaged in research partnerships with UCF or USF may be eligible for matching funds from The Corridor’s Matching Grants Research Program .
Tapping into America's Seed Fund to Accelerate Small Business R&D For an overview of the SBIR/STTR programs and how to partner with USF faculty, please view our How to Leverage Federal Innovation Funding & University Collaboration from Corridor Program Director, Elizabeth Nelson. For general information, including detailed eligibility requirements, visit the SBIR/STTR website Overview of agency-specific resources available here .
Determine if SBIR funding is right for your company using this checklist Small businesses are required to register with participating agencies on at least three various platforms. Most agencies advise allowing at least four-to-six weeks to complete the registration process. Use this guide to determine which registrations are necessary.
USF faculty considering SBIR/STTR engagement should review Sponsored Research's policy guidance here .
BBC Entrepreneurial Training & Consulting provides useful training webinars and resources Free Pre-Recorded Webinars FL FAST: Florida’s First Centralized SBIR/STTR Support System for Entrepreneurs Powered by a grant from the U.S. Small Business Administration’s Federal and State Technology (FAST) Partnership Program , The Corridor’s FL FAST initiative is Florida’s first centralized support system for companies pursuing SBIR/STTR FL FAST serves small businesses statewide pursuing research and innovation activities in The Corridor’s 23-county region and beyond.
Services include in-person and virtual workshops, and one-on-one assistance to meet business needs in key areas, such as topical award identification, budget preparation, proposal review, support letters and research partnerships.
FL FAST also serves as an important resource for entrepreneurial support organizations, sharing resources, events, solicitations, legislative actions and other information relevant to driving SBIR/STTR outcomes. To access training materials, webinars and other resources, please visit the Corridor's SBIR/STTR Resource Page.
To register for upcoming webinars, training cohorts, or request direct support, please visit the Corridor's FL FAST page . The National Science Foundation runs a large SBIR/STTR program that covers a wide variety of topics . This is often a good starting point for companies interested in participating in this funding program for the first time.
The NSF requires interested companies to submit a short project pitch before applying. Agency staff vet these pitches and will invite appropriate projects to apply for a Phase I award. Companies then have one year to submit a full proposal.
You can learn more about the NSF Project Pitch process on their website and through the reference video below from The Corridor. SBIR/STTR Agency Specific Application Support Programs Several federal agencies provide support and programming to assist first time applicants as they submit an SBIR/STTR proposal. Below is a summary of these programs.
National Institutes of Health Applicant Assistance Program National Institute on Aging Start-up Challenge Department of Energy Phase 0 The National Institute of Allergy and Infectious Diseases (NIAID) Small Business Applicant NIAID Entrepreneurship and Grantsmanship Training Program for First-Time Entrepreneurs NIAID Sample Applications National Institutes of Health (NIH) Applicant Assistance Program (AAP) A free, guided 10-week program designed to help first time applicants.
One of the main goals of the AAP is to increase participation in the SBIR and STTR programs by businesses that are owned or controlled by individuals who are traditionally underrepresented The AAP provides 10 weeks of coaching and customized assistance at no cost to participants.
Selected small businesses can receive: Needs assessment/small business mentoring Assistance with required registrations Phase I application preparation support More Information: https://seed. nih.
gov/small-business-funding/aap National Institute on Aging (NIA) Start-Up Challenge The NIA has a strong commitment to fostering diversity in aging research-inspired entrepreneurship and in encouraging participation of underrepresented groups in the NIA SBIR/STTR programs.
To support this commitment, NIA is hosting the Start-Up Challenge and Accelerator to stimulate innovation and foster diversity in aging research and development by providing cash prizes and non-cash prizes, such as strategic resources provided through an accelerator program, that will help participants overcome barriers to participating in life science entrepreneurship.
This Challenge invites submissions from researchers and entrepreneurs with a demonstrated need for entrepreneurial training More Information: https://www. nia. nih.
gov/research/sbir/startup-challenge Department of Energy Phase 0 Small Business Application Assistance The U.S. DOE offers its Phase 0 services to a limited number of first-time DOE SBIR/STTR Phase I participants. This support, provided by Dawnbreaker is designed to assist eligible small businesses navigate the complexities of the SBIR/STTR proposal process.
During each Phase I Release (normally July/October), DOE sponsors a full menu of services to a limited number of pre-approved small businesses. Selected small businesses can receive: Letter of Intent (LOI) Review Phase I proposal preparation support More Information: https://doephase0. dawnbreaker.
com/ Academic Partnership Engagement Experiment (APEX) Small Business Innovation Research (SBIR) and Technology Transfer (STTR) process navigation services involve team matchmaking Team matchmaking entails locating and connecting potential collaborators within the Consulting entails supporting entrepreneurial and academic researchers with the best support possible during their pursuit of Department of the Air Force SBIR/STTR funding, from pre-proposal to post-award.
APEX is funded by the Department of the Air Force to provide SBIR/STTR process navigation services at no cost to qualifying small businesses More Information: https://apex-innovates.
org/services/sbirsttr-process-navigation The National Institute of Allergy and Infectious Diseases (NIAID) Small Business Applicant The NIAID Small Business AAP will offer support for companies planning to apply for a NIAID Phase I, Phase II/IIB, Fast Track, or Direct-to-Phase II Small Business Innovation Research STTR/ STTR Awards at no cost.
Participants in the NIAID AAP will work one-on-one with a Senior Consultant from Foresight Science & Technology, who will help you prepare your proposal with such services as Outlines and Checklist, Registration Guidance, Review and Feedback on Commercialization Plan, Research Strategy, Budget, and/or other Attachments. More information: https://foresightst.
com/niaid-aap/ Entrepreneurship and Grantsmanship Training Program for First-Time Entrepreneurs Foresight Science & Technology is excited to be working alongside the National Institute of Allergy and Infectious Disease (NIAID) in association with the National Heart Lung and Blood Institute (NHLBI) to provide training and resources for a new Innovator to Entrepreneur Program (ITEP).
This program will benefit inventors developing technically sound, innovative products but having little to no experience in turning their inventions into a business and in business grantsmanship.
ITEP will assist these aspiring entrepreneurs by providing them with cohort-based comprehensive training covering the key elements of company launch, business strategy development, IP protection, market research and customer discovery, startup financing and SBIR/STTR grantsmanship. This training will be provided at no cost to all participants. More information: https://foresightst.
com/niaiditepannouncement/ The NSF requires interested companies to submit a short project pitch before applying. Agency staff vet these pitches and will invite appropriate projects to apply for a Phase I award. The agency also hosts virtual office hours and recorded program overviews.
More Information: https://seedfund. nsf. gov/resources/applicants/ NASA provides a detailed resource library organized by proposal Phases.
Phase 0 (preapplication resources) include webinars and infographics on proposal submissions, common mistakes, tips, and budget guidance. More Information: https://sbir. nasa.
gov/resource-library The Department of Defense provides a broad range of resources for its branches SBIR/STTR program. Resources include job aids and proposal templates. More Information: https://www.
dodsbirsttr. mil/submissions/learning-support/training-materials National Institute on Aging (NIA) Resources The NIA provides a range of small business applicant resources including: sample applications, tips for applicants, research priorities and more. More Information: https://www.
nia. nih. gov/research/sbir/small-business-applicant-resources National Institute of Allergy and Infectious Diseases (NIAID) Sample Applications Several NIAID investigators have graciously agreed to share their exceptional applications and summary statements as samples to help the research community.
At the link you will find a list of applications, example forms, sharing plans, letters, emails, and See Sample Applications and More: https://www. niaid. nih.
gov/grants-contracts/sample-applications
According to the current listing, eligibility includes: Small businesses operating within designated high-tech regions in Florida. Confirm the full requirements in the official notice before applying.
Florida High Tech Corridor's Small Business Innovation Research and Small Business Technology Transfer Awards is funded by Florida High Tech Corridor. Verify program details on the funder's official page before applying.
This opportunity targets applicants in Florida. If your organization operates elsewhere, check the official notice for location requirements.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly.
Past winners and funding trends for this program
On September 3, 2026 — six days before the FY2027 Pioneer deadline — NIH posted forecast records for the entire FY2028 High-Risk, High-Reward program. The slate is nearly flat against FY2027, Transformative loses a slot, and the dollar figures quietly assume full negotiated indirect rates.
Read articleThe U.S. Government Policy for Stopping High-Risk Life Sciences Research, released July 28, 2026 under EO 14292 and implemented at NIH through NOT-OD-26-101, replaces mitigation with prohibition. It bans dangerous gain-of-function research outright, gates potential DGOF behind government-wide review, and creates International Research of Concern — a research-security regime wearing biosafety clothing. Penalties run to five-year debarment and False Claims Act exposure.
Read articleThe FY2027 Common Fund slate is roughly $44 million across about 54 awards — Pioneer at $8M for 7, Transformative at $8M for 7, Early Independence at $5.7M for 10, and New Innovator's 30 already closed on August 17. Early Independence skipped FY2026 entirely, and its degree-eligibility window now spans 29 months to absorb the gap.
Read article