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HHMI Investigators Program is a prestigious long-term research appointment from the Howard Hughes Medical Institute (HHMI) that selects established scientists pushing the frontiers of basic biological and biomedical sciences. Selected investigators receive their full salary, comprehensive benefits, and substantial research support for renewable seven-year terms.
Eligibility requires a minimum of seven years of independent faculty experience. Unlike traditional grants, HHMI invests in the scientist rather than a specific project, offering investigators the freedom to pursue ambitious, high-risk research that may not fit conventional funding models. This program is among the most competitive and distinguished research appointments in the life sciences.
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Mid-Career & Senior Faculty Program | HHMI Investigators HHMI Investigators are established researchers, including physician-scientists, who push the boundaries of basic biological and biomedical sciences, working across many scientific disciplines in a wide range of organisms at institutions across the US .
Investigators create inclusive, collaborative research environments that prepare early career scientists for future success, and their fundamental discoveries have been broadly recognized by the scientific community, including Nobel Prizes awarded to more than 30 current or emeriti Investigators .
Investigators are HHMI employees who receive full salary and benefits from the Institute while maintaining academic appointments and labs at their home institutions.
Once appointed to a seven-year, renewable term, Investigators receive financial support for their research, access to capital equipment funds, and induction into the vibrant HHMI community of Investigators, Freeman Hrabowski Scholars , Hanna Gray and Gilliam Fellows , and more.
Eligibility for the program has been expanded to include scientists who have held their first independent faculty position for a minimum of seven years, with no upper career-stage limit. Join our email list for program and competition news. Life as an HHMI Investigator Freedom to pursue your boldest ideas Each Investigator receives generous support over a seven-year term, renewable indefinitely pending successful review.
Investigators remain affiliated with their institution and become employees of HHMI, receiving their full salary, benefits, and research budgets through the Institute. Robust equipment allotment As a supplement to core support, Investigators may also submit capital equipment requests to the Institute for scientific equipment necessary to their research.
Join a vibrant scientific community Investigators are part of a large, active community of HHMI scientists spanning career stages who collaborate and attend scientific meetings to share new research. Over a 50-year career, former HHMI scientist and leader David Clapham reshaped our understanding of ion channels by relentlessly pursuing experimental evidence across scientific disciplines.
HHMI Investigator Karolin Luger is being honored by the Vilcek Foundation for her research into nucleosomes — the DNA-packaging structures inside cells — that has led to the development of innovative drugs for treating diseases, including cancer. HHMI Investigator Kevan Shokat and his lab are charting new therapies to outmaneuver drug resistance and better target common cancer cell mutations.
A team of researchers led by HHMI Investigator Michael Rosen has captured the most detailed images yet of the molecules in chromatin condensates — droplet-like structures of compacted DNA. Get HHMI News in your inbox
Based on current listing details, eligibility includes: Scientists who have held their first independent faculty position for a minimum of seven years, with no upper career-stage limit. Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates Funding amounts vary based on project scope and sponsor guidance. Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
The current target date is rolling deadlines or periodic funding windows. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.
Federal grant success rates typically range from 10-30%, varying by agency and program. Build a strong proposal with clear objectives, measurable outcomes, and a well-justified budget to improve your chances.
Requirements vary by sponsor, but typically include a project narrative, budget justification, organizational capability statement, and key personnel CVs. Check the official notice for the complete list of required attachments.
Yes — AI tools like Granted can help research funders, draft proposal sections, and check compliance. However, always review and customize AI-generated content to reflect your organization's unique strengths and the specific requirements of the solicitation.
Review timelines vary by funder. Federal agencies typically take 3-6 months from submission to award notification. Foundation grants may be faster, often 1-3 months. Check the program's timeline in the official solicitation for specific dates.
Many federal programs offer multi-year funding or allow competitive renewals. Check the official solicitation for continuation and renewal policies. Non-competing continuation applications are common for multi-year awards.