Investigator Initiated Research Grant (R01) is sponsored by National Institute of Mental Health (NIMH), National Institutes of Health (NIH). This is the most common mechanism used by NIH to support research. It is open to applicants throughout their research careers, including those applying for the first time.

It supports research projects in all NIMH-relevant scientific areas.

Research Project (R01) | Grants & Funding U.S. Department of Health and Human Services National Institutes of Health To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies. The Research Project (R01) is NIH's most commonly used grant program for independent research projects. Are you an early stage investigator (ESI)?

If all the PD/PIs on an R01 (or R01-equivalent ) application have ESI status on the date an application is submitted, the application will be flagged as ESI and will receive special consideration during the review and funding process. See Early Stage Investigator (ESI) Policies to learn more. The Stephen I.

Katz Early Stage Investigator Research Project Grant supports an innovative project in an area of science that represents a change in research direction for an early stage investigator and for which no preliminary data Allowable costs include (but are not limited to): Salary and fringe benefits for Principal Investigator, key personnel, and other essential personnel Alterations and renovations Publications and miscellaneous costs Facilities and Administrative costs (indirect costs) Application and Submission Information R01 Parent Announcements are available.

Not all NIH institutes and centers participate on all parent announcements. Check the participating organization in the funding opportunity before applying. Application Characteristics R01 application budgets are generally not limited but need to reflect the actual needs of the proposed project.

Any opportunity-specific budget limits are indicated in Part 2. Section 2. Award Budget of the funding opportunity.

NIH's Modular Budget Policy applies to R01 applications submitted by domestic organizations. Applications are generally awarded for 1-5 budget periods, each normally 12 months in duration. Applications can be renewed by competing for an additional project period.

After identifying a funding opportunity, follow guidance in the How to Apply – Application Guide instruction call-outs, except where instructed to do otherwise in the funding opportunity or related notices. Standard Due Dates apply.

AIDS and AIDS-Related Applications Beginning with applications for Advisory Council Review in January 2027 (i.e., application due dates on or after May 25, 2026), NIH will no longer accept applications submitted on dedicated AIDS application due dates. ( NOT-OD-26-029 ) Standard Application Due Dates (when applicable) Participating Funding Organizations Each funding opportunity specifies the participating organizations.

Applications must fit within the mission of at least one participating funding organization and meet all opportunity-specific requirements. The following funding organizations participate on at least one active funding opportunity.

Division of Program Coordination, Planning and Strategic Initiatives, Office of Disease Prevention Division of Program Coordination, Planning and Strategic Initiatives, Office of Research Infrastructure Programs Eunice Kennedy Shriver National Institute of Child Health and Human Development National Cancer Institute National Center for Advancing Translational Sciences National Center for Complementary and Integrative Health National Heart, Lung, and Blood Institute National Human Genome Research Institute National Institute of Allergy and Infectious Diseases National Institute of Arthritis and Musculoskeletal and Skin Diseases National Institute of Biomedical Imaging and Bioengineering National Institute of Dental and Craniofacial Research National Institute of Diabetes and Digestive and Kidney Diseases National Institute of Environmental Health Sciences National Institute of General Medical Sciences National Institute of Mental Health National Institute of Neurological Disorders and Stroke National Institute of Nursing Research National Institute on Aging National Institute on Alcohol Abuse and Alcoholism National Institute on Deafness and Other Communication Disorders National Institute on Drug Abuse National Institute on Minority Health and Health Disparities National Library of Medicine Office of Behavioral and Social Sciences Research Office of Research on Women's Health Office of The Director, National Institutes of Health Tribal Health Research Office Your organization's sponsored programs office or grants administrators can answer many internal and agency policy and process questions.

Understand NIH Staff Roles details how and when to find the right NIH contacts: Before you apply, check your chosen funding opportunity for application submission, scientific/research, peer review, and financial/grants management contacts. After you apply, find NIH staff assignments in the Status module of eRA Commons . For technical issues E-mail OER Webmaster