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Annual submission window October 1-14. Conference proposals: 8 months prior (US), 12 months prior (international). Revised proposals must wait 12 months after decline.
Mathematical Biology Program is a grant from NSF that funds research in applied and computational mathematics with relevance to the biological and life sciences. The program supports projects across all areas of mathematical sciences that demonstrate strong integration between mathematics and biology. Successful proposals must show mathematical innovation, biological relevance and significance, and rigorous interdisciplinary methods.
Projects may include development of new mathematical theories, methodologies, and computational tools aimed at advancing the life sciences. Eligible applicants are typically academic researchers and institutions. Award amounts and deadlines vary by submission cycle.
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Mathematical Biology | NSF - U.S. National Science Foundation NSF's implementation of the revised 2 CFR NSF Financial Assistance awards (grants and cooperative agreements) made on or after October 1, 2024, will be subject to the applicable set of award conditions, dated October 1, 2024, available on the NSF website .
These terms and conditions are consistent with the revised guidance specified in the OMB Guidance for Federal Financial Assistance published in the Federal Register on April 22, 2024.
Important information for proposers All proposals must be submitted in accordance with the requirements specified in this funding opportunity and in the NSF Proposal & Award Policies & Procedures Guide (PAPPG) that is in effect for the relevant due date to which the proposal is being submitted. It is the responsibility of the proposer to ensure that the proposal meets these requirements.
Submitting a proposal prior to a specified deadline does not negate this requirement.
Updates to NSF Research Security Policies On July 10, 2025, NSF issued an Important Notice providing updates to the agency's research security policies, including a research security training requirement, Malign Foreign Talent Recruitment Program annual certification requirement, prohibition on Confucius institutes and an updated FFDR reporting and submission timeline.
Supports research in areas of applied and computational mathematics relevant to the biological and life sciences. Supports research in areas of applied and computational mathematics relevant to the biological and life sciences. The Mathematical Biology Program supports research in all areas of mathematical sciences with relevance to the biological sciences.
Successful proposals must demonstrate mathematical innovation, biological relevance and significance, and strong integration between mathematics and biology. Some projects of interest to the Mathematical Biology Program may include development of mathematical theories, methodologies, and tools traditionally seen in other disciplinary programs within the Division of Mathematical Sciences.
In general, if a proposal is appropriate for review by more than one NSF program, it is advisable to contact the program officers handling each program to determine when and where the proposal should be submitted and to facilitate the review process. The Mathematical Biology Program regularly seeks joint reviews of proposals with programs in the Directorates of Biological Sciences and other relevant programs.
Investigators are encouraged to discuss their project with program officers in relevant areas to determine whether it could be considered by more than one program. Research in Undergraduate Institutions (RUI) Investigators submitting an RUI proposal should read the RUI solicitation (link below), as the rules for proposal format may deviate from the Proposal & Award Policies & Procedures Guide (PAPPG).
EAGER and RAPID Proposals Prior to submitting proposals for EArly-concept Grants for Exploratory Research (EAGER) or Rapid Response Research (RAPID), Investigators must contact the cognizant program directors. Requests for Award Supplements Principal Investigators are encouraged to contact the cognizant program director prior to submission of a proposal for an award supplement. See the PAPPG for more information.
Investigators should carefully read the program solicitation, "Conferences and Workshops in the Mathematical Sciences," (link below) to obtain important information regarding the substance of proposals for conferences, workshops, summer/winter schools, and similar activities.
To facilitate timely notification of the availability of support: proposals for conferences, workshops, etc., to be held in the US must be submitted 8 months in advance of the conference date; proposals to support group travel to meetings outside the US must be submitted 12 months in advance of the meeting date.
November 25, 2024 - Emerging Mathematics in Biology Webinar Additional program resources Frequently Asked Questions (FAQs) for Removal of Deadlines for the Mathematical Biology Program Emerging Mathematics in Biology (eMB) Incorporating Human Behavior in Epidemiological Models (IHBEM) Mathematical Modeling of Policy Options for Evolving Public Health Challenges (MPOPHC) Research in Undergraduate Institutions (RUI) and Research Opportunity Awards (ROA) Conferences and Workshops in the Mathematical Sciences Proposal & Award Policies & Procedures Guide (PAPPG) Awards made through this program Browse projects funded by this program Map of recent awards made through this program Joint DMS/NIGMS Initiative to Support Research at the Interface of the Biological and Mathematical Sciences (DMS/NIGMS) Collaborative Research in Computational Neuroscience (CRCNS) Focused Research Groups in the Mathematical Sciences (FRGMS) Research Training Groups in the Mathematical Sciences (RTG) Directorate for Mathematical and Physical Sciences (MPS) Division of Mathematical Sciences (MPS/DMS)
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Based on current listing details, eligibility includes: Universities and research institutions. Research in Undergraduate Institutions (RUI) proposals also eligible. Must follow NSF PAPPG guidelines. Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates Varies Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
The current target date is October 14, 2025. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.
Federal grant success rates typically range from 10-30%, varying by agency and program. Build a strong proposal with clear objectives, measurable outcomes, and a well-justified budget to improve your chances.
Requirements vary by sponsor, but typically include a project narrative, budget justification, organizational capability statement, and key personnel CVs. Check the official notice for the complete list of required attachments.
Yes — AI tools like Granted can help research funders, draft proposal sections, and check compliance. However, always review and customize AI-generated content to reflect your organization's unique strengths and the specific requirements of the solicitation.
Review timelines vary by funder. Federal agencies typically take 3-6 months from submission to award notification. Foundation grants may be faster, often 1-3 months. Check the program's timeline in the official solicitation for specific dates.
Many federal programs offer multi-year funding or allow competitive renewals. Check the official solicitation for continuation and renewal policies. Non-competing continuation applications are common for multi-year awards.
Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science (SCH) is sponsored by National Science Foundation (NSF) & National Institutes of Health (NIH). This interagency program supports transformative high-risk, high-reward advances in computer and information science, engineering, mathematics, statistics, behavioral and/or cognitive research to address pressing questions in the biomedical and public health communities. It emphasizes scientific and engineering innovations by interdisciplinary teams developing novel methods to intelligently collect, sense, connect, analyze, and interpret data from individuals, devices, and systems to enable discovery and optimize health, particularly leveraging machine learning and artificial intelligence.
Small Business Innovation Research (SBIR) & Small Business Technology Transfer (STTR) Programs is sponsored by National Science Foundation (NSF). America's Seed Fund, powered by NSF, offers non-dilutive funding to startups and small businesses for use-inspired research and development (R&D) of unproven, leading-edge technology innovations that address societal challenges. The program aims to transform scientific and engineering discoveries into products and services with commercial and societal impact.
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