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PAR-26-121 (EI/NI): multiple windows in 2026-2028. PAR-23-145 (ESI): through February 3, 2026.
Maximizing Investigators' Research Award (MIRA) (R35 - Clinical Trial Optional) is sponsored by National Institute of General Medical Sciences (NIGMS). Maximizing Investigators' Research Award (MIRA) (R35 - Clinical Trial Optional) is a grant from the National Institute of General Medical Sciences (NIGMS) that funds biomedical research conducted within an investigator's laboratory.
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Maximizing Investigators' Research Award (MIRA) (R35) | National Institute of General Medical Sciences MIRA provides support for research in an investigator's laboratory that falls within the mission of NIGMS . The goal of MIRA is to increase the efficiency of NIGMS funding by providing investigators with greater stability and flexibility, thereby enhancing scientific productivity and the chances for important breakthroughs.
The program will also help distribute funding more widely among the nation's highly talented and promising investigators. MIRA grants will generally be for 5 years, for both established investigators/ new investigators and early stage investigators . Early stage investigators should apply through PAR-27-032 .
MIRA for Established and New Investigators (EIs and NIs) New NOFO Published: PAR-26-121 See below for MIRA for Early-Stage Investigators (ESIs). PAR-26-121 – Applications accepted in 2026-2028 MIRA Eligibility Decision Tree For more information on MIRA for established investigators contact Ashley Barnes, Ph. D.
, and Baishali Maskeri, Ph. D. , at NIGMS_EINIMIRA@nigms.
nih. gov MIRA for Early Stage Investigators (ESIs) PAR-27-032 - Applications accepted through February 6, 2029 FAQs About PAR-27-032 NOT-GM-26-006: Notice of Informational Webinar on the NIGMS MIRA for ESIs (R35) Eligibility: NIH Definitions of Early Stage Investigators and Related Policies and Procedures For more information on MIRA for ESIs contact Michelle R. Bond, Ph.
D. , and Marc Rigas, Ph. D.
, at NIGMS-ESIMIRA@nigms. nih. gov .
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According to the current listing, eligibility includes: Nonprofits, Universities, State/local governments. Confirm the full requirements in the official notice before applying.
Applications for Maximizing Investigators' Research Award (MIRA) (R35 - Clinical Trial Optional) are due May 27, 2028. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
Maximizing Investigators' Research Award (MIRA) (R35 - Clinical Trial Optional) is funded by National Institute of General Medical Sciences (NIGMS). Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly.
NCI Continuing Umbrella of Research Experiences (CURE) Academic Career Excellence (ACE) Award (K32) is a grant from the National Cancer Institute (NCI) that funds early postdoctoral fellows from diverse backgrounds, including underrepresented groups, to pursue research training in cancer-related fields. The K32 award supports fellows within 12 months prior to transitioning into, or within the first two years of, a postdoctoral position. The program, operated through NCI's Center to Reduce Cancer Health Disparities (CRCHD), aims to enhance the pool of qualified diverse cancer researchers. Beginning with the June 12, 2025 due date, the CURE ACE Award is available in both Independent Clinical Trial Required and Independent Clinical Trial Not Allowed versions. Eligible applicants must be U.S. citizens or permanent residents at time of award.
Innovation Grant is a grant from the Delta Dental of Arizona Foundation that funds nonprofit organizations pursuing unique, high-impact projects that improve health and wellness in Arizona communities. This two-year award supports original initiatives with measurable real-world impact, including programs serving underserved and uninsured populations through oral health education, disease prevention, and nutritional access. Projects must demonstrate the potential to make a meaningful difference in the community and stand apart from conventional approaches. Eligible applicants are Arizona-based nonprofit organizations. Awards total $100,000 per recipient over two years. The 2026 application cycle closed October 16, 2025, with recipients notified in late 2025 and funding made available shortly after.
Cummings Foundation raised its annual local grant program from $30M to $35M and is now awarding nearly all of it as unrestricted general operating support — including 25 grants paid over a full 10 years. Letters of inquiry for the 2027 cycle opened July 15 and close September 16, 2026. Here is who qualifies, how the multi-year structure works, and why the shift to unrestricted, decade-long funding matters more than the dollar increase.
Read articleThe Clif Family Foundation's Open Call funds $5,000 to $50,000 in general operating support — money a nonprofit can spend on rent, salaries, or whatever keeps the lights on — for grassroots groups working on regenerative farming, climate justice, food access, and the environment. Applications close August 3, 2026. For small nonprofits, unrestricted funding is worth more than its face value. Here's how to compete for it.
Read articleNSF's Arctic Research Opportunities solicitation funds roughly 75 awards a year — up to $50 million — across six program areas from natural sciences to social sciences to the Arctic Observing Network. The July 15, 2026 target date is not a hard deadline, and understanding that distinction is the first strategic decision an Arctic researcher makes. Here is how the six doors differ and how to choose the right one.
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