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Find similar grantsMPS Core Research Programs is sponsored by National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS). The NSF Directorate for Mathematical and Physical Sciences (MPS) supports numerous core research programs spanning astronomical sciences, chemistry, materials research, mathematical sciences and physics.
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Directorate for Mathematical and Physical Sciences (MPS) | NSF - U.S. National Science Foundation Directorate for Mathematical and Physical Sciences (MPS) View image credit & caption Directorate for Mathematical and Physical Sciences (MPS) The U.S. National Science Foundation Directorate for Mathematical and Physical Sciences (NSF MPS) is one of the preeminent federal forces behind over 75 years of major scientific breakthroughs and innovations — from the discovery of new properties of energy and matter to the creation of entirely new fields of mathematics.
NSF MPS supports fundamental research in astronomical sciences, chemistry, materials, mathematical sciences and physics. MPS also manages ambitious, multidisciplinary research centers and institutes focused on major scientific challenges. The directorate supports fundamental science and research infrastructure that advances scientific knowledge and enhances the nation's economic growth, security and quality of life.
MPS investments are also building the scientific workforce of the future by providing specialized training, education and mentorship opportunities in labs across the U.S. NSF-supported researchers expand storage capabilities of DNA New leadership roles and appointments in NSF MPS A message from NSF MPS leadership on reorganization and merit review changes Tiny crystals, huge impact — NSF launches new nanocrystals research center NSF and industry partners fund new research to use emerging data analytics tools for more efficient polymer manufacturing Podcast: Photonic quantum chips promise fast future Podcast: The future of quantum computing Podcast: AI-powered labs accelerating scientific discovery Friday, May 8, 2026, 3:00 p.
m. – 4:00 p. m.
MPS Chemistry Quarterly Office Hours Q&As and information sessions Join MPS staff for a presentation on the NSF CAREER program Thursday, May 28, 2026, 3:00 p. m. – 4:00 p.
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NSF EPSCoR Graduate Fellowship Program Office Hours for Potential Fellows Q&As and information sessions NSF EPSCoR Graduate Fellowship Program Office Hours for Potential Fellows Advancing Artificial Intelligence (AI) Agent Ecosystems through the National Science Foundation Pathways to Enable Secure Open-Source Ecosystems (NSF PESOSE) Program Next Required Due Date: See letter for details Pathways to Enable Secure Open-Source Ecosystems (PESOSE) Next Required Due Date: September 1, 2026 National Quantum and Nanotechnology Infrastructure (NQNI) Next Required Due Date: May 14, 2026 Materials Research Science and Engineering Centers (MRSEC) View all MPS opportunities MPS supports the ground-based exploration of space.
From asteroids to black holes, this work enables the discovery and understanding of objects and phenomena within our solar system, the Milky Way galaxy and other galaxies, and the entire universe. MPS supports fundamental discovery, invention and innovation in the chemical sciences.
This work creates a strong scientific foundation for future technologies and the chemical industry, which is central to the U.S. economy and our daily lives. MPS supports fundamental understanding of materials, their properties and their potential applications. Materials research provides critical building blocks for technology and innovation, from new types of electronics and batteries to medical devices and body armor.
MPS supports multiple research programs at the frontiers of discovery in theoretical and applied mathematical sciences. Mathematical sciences play an essential role in all fields of science and technology and underpin many aspects of society and security, from weather forecasting to cryptography.
MPS supports physics research that enables human understanding of the fundamental aspects of nature at all scales, from quantum-scale effects inside atoms to the dark energy that spans the entire universe. Breakthroughs in physics have led to technologies including GPS, MRI and quantum computers.
NSF supports research facilities that provide scientists with unique instruments and capabilities to explore the physical universe, including multiple astronomy observatories, the NSF National High Magnetic Field Laboratory, particle detectors at the Large Hadron Collider, and others.
Based on current listing details, eligibility includes: Academic institutions, research centers, and individual researchers. Applicants should confirm final requirements in the official notice before submission.
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Foundations for Digital Twins as Catalyzers of Biomedical Technological Innovation (FDT-BioTech) is sponsored by National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS). This program supports inherently interdisciplinary research projects that underpin the mathematical and engineering foundations behind the development and use of digital twins and synthetic data in biomedical technological innovation.
Foundations for Digital Twins as Catalyzers of Biomedical Technological Innovation (NSF FDT-BioTech) is sponsored by National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS), Division of Mathematical Sciences, and Office of Advanced Cyberinfrastructure. This program supports interdisciplinary research at the intersection of AI, computational modeling, and biomedical innovation, funding mathematical and engineering foundations for digital twins and synthetic data in healthcare.