NIH Building Interdisciplinary Research Careers in Women's Health (BIRCWH) (K12 Clinical Trial Optional) is sponsored by National Institutes of Health (NIH) Office of Research on Women's Health (ORWH). This program supports the career development of junior faculty members (BIRCWH Scholars) who have recently completed clinical training or postdoctoral fellowships and are engaged in interdisciplinary basic, translational, behavioral, clinical, and/or health services research rel…

RFA-OD-24-013: Building Interdisciplinary Research Careers in Women's Health (BIRCWH) (K12 Clinical Trial Optional) This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission. Department of Health and Human Services Part 1.

Overview Information Participating Organization(s) National Institutes of Health ( NIH ) Components of Participating Organizations Office of Research on Women's Health ( ORWH ) National Institute on Alcohol Abuse and Alcoholism ( NIAAA ) National Institute of Allergy and Infectious Diseases ( NIAID ) National Institute of Arthritis and Musculoskeletal and Skin Diseases ( NIAMS ) Eunice Kennedy Shriver National Institute of Child Health and Human Development ( NICHD ) National Institute of Dental and Craniofacial Research ( NIDCR ) National Institute on Drug Abuse ( NIDA ) National Cancer Institute ( NCI ) All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers.

The following NIH Offices may co-fund applications assigned to those Institutes/Centers. Office of Dietary Supplements ( ODS ) Office of Data Science Strategy ( ODSS ) Funding Opportunity Title Building Interdisciplinary Research Careers in Women's Health (BIRCWH) (K12 Clinical Trial Optional) K12 Physician Scientist Award Program (PSA) March 31, 2025 - This funding opportunity was updated to align with agency priorities.

Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission. April 04, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025. See Notice NOT-OD-24-084 August 31, 2022 - Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023.

See Notice NOT-OD-22-198 . August 5, 2022 - Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189 .

Funding Opportunity Number (FON) Companion Notice of Funding Opportunity See Section III. 3. Additional Information on Eligibility.

Assistance Listing Number(s) 93. 313, 93. 273, 93.

846, 93. 279, 93. 866, 93.

121, 93. 398, 93. 855 Notice of Funding Opportunity Purpose The NIH Office of Research on Women's Health (ORWH) and participating NIH Institutes, Centers, and Offices (ICOs) invite institutional career development award applications for Building Interdisciplinary Research Careers in Women's Health (BIRCWH) Career Development Programs, hereafter termed "Programs".

Programs will support mentored research career development of junior faculty members, known as BIRCWH Scholars, who have recently completed clinical training or postdoctoral fellowships, and who will be engaged in interdisciplinary basic, translational, data science, behavioral, clinical, and/or health services research relevant to the health of women and, where appropriate, the use of both sexes to better understand the influence of sex as a biological variable on health and disease.

This Notice of Funding Opportunity (NOFO) allows appointment of Scholars (K12) proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary clinical trial; or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development.

Open Date (Earliest Submission Date) Letter of Intent Due Date(s) Renewal / Resubmission / Revision (as allowed) AIDS - New/Renewal/Resubmission/Revision, as allowed All applications are due by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Required Application Instructions It is critical that applicants follow the Training (T) Instructions in the How to Apply - Application Guide , except where instructed to do otherwise (in this NOFO or in a Notice from the NIH Guide for Grants and Contracts ). Conformance to all requirements (both in the How to Apply - Application Guide and the NOFO) is required and strictly enforced.

Applicants must read and follow all application instructions in the How to Apply - Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the How to Apply - Application Guide , follow the program-specific instructions. Applications that do not comply with these instructions may be delayed or not accepted for review.

There are several options available to submit your application through Grants. gov to NIH and Department of Health and Human Services partners. You must use one of these submission options to access the application forms for this opportunity.

Use the NIH ASSIST system to prepare, submit and track your application online. Use an institutional system-to-system (S2S) solution to prepare and submit your application to Grants. gov and eRA Commons to track your application.

Check with your institutional officials regarding availability. Workspace to prepare and submit your application and eRA Commons to track your application. Part 1.

Overview Information Part 2. Full Text of Announcement Section I. Notice of Funding Opportunity Description Section II.

Award Information Other Award Budget Information Section III. Eligibility Information Section IV. Application and Submission Information Section V.

Application Review Information Section VI. Award Administration Information Section VII. Agency Contacts Section VIII.

Other Information Part 2. Full Text of Announcement Section I. Notice of Funding Opportunity Description The overall goal of the NIH Research Career Development programs is to help ensure that a pool of highly trained scientists is available in appropriate scientific disciplines to address the Nation’s biomedical behavioral and clinical research needs.

More information about Career programs may be found at the NIH Extramural Training Mechanisms website. This NOFO encourages applications from organizations that propose innovative institutional research career development programs in the mission area(s) of the NIH.

The proposed institutional research career development program may complement other, ongoing research training and career development programs at the applicant institution, but the proposed career development experiences must be distinct from those career development programs currently receiving Federal support.

Investigators proposing NIH-defined clinical trials may refer to the Research Methods Resources website for information about developing statistical methods and study designs.

Note : This Notice of Funding Opportunity (NOFO) allows appointment of Scholars (K12) proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary clinical trial; or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development.

In order to expand the number and skills of Women's Health researchers, the NIH Office of Research on Women's Health (ORWH) and participating NIH Institutes and Centers (ICs) invite institutional career development award applications for the Building Interdisciplinary Research Careers in Women's Health (BIRCWH) Career Development Program.

Each program will support mentoring the research career development of junior faculty members, known as BIRCWH Scholars, who have recently completed clinical training or postdoctoral fellowships, and who will be engaged in interdisciplinary basic, translational, behavioral, clinical, and/or health services research relevant to the health of women and, where appropriate, the use of both sexes to better understand the influence of sex as a biological variable on health and disease.

The Office of Research on Women's Health (ORWH) serves as a focal point for women's health research at the National Institutes of Health ( NIH ). The ORWH works in partnership with the NIH institutes, centers, and offices, as well as with federal agencies, including the Food and Drug Administration, to ensure that women's health research is an integral part of the scientific framework throughout the scientific community .

This NOFO encourages applications from organizations that propose creative and innovative institutional research career development programs in the mission area(s) of the NIH.

The program will support mentored research and career development opportunities of junior faculty, known as BIRCWH Scholars, who have recently completed clinical training or postdoctoral fellowships, and who will be engaged in interdisciplinary basic, translational, behavioral, clinical, and/or health services research relevant to the health of women and, where appropriate, the use of both sexes to better understand the influence of sex as a variable on health and disease – more information can be found on the ORWH website, https://orwh.

od. nih. gov .

Within the framework of this Program's longstanding commitment to excellence and the projected need for strong teams to advance science, attention must be given to recruiting prospective Scholars from all backgrounds.

The proposed institutional research career development program may complement other, ongoing research training and career development programs at the applicant institution, but the proposed career development experiences must be distinct from those career development programs currently receiving Federal support.

The objectives of this BIRCWH initiative are to increase the number and skills of investigators through a mentored research and career development experience leading to an independent scientific career that will benefit the health of women; advance research on sex influences on health; and encourage interdisciplinary research methodology.

This BIRCWH NOFO will provide opportunities for an interdisciplinary, mentored career development experience that would otherwise not be available to facilitate the transition to research independence for junior faculty researchers who are conducting interdisciplinary research relevant to the health of women. The BIRCWH Program is built around three pillars: interdisciplinary research, mentoring, and career development.

Interdisciplinary research, as defined by the National Academy of Sciences (NAS), is a mode of research that integrates information, data, techniques, tools, perspectives, concepts, and/or theories from two or more disciplines or bodies of specialized knowledge to advance fundamental understanding, or to solve problems whose solutions are beyond the scope of a single discipline or area of research practice.

As such, interdisciplinary science teams work to advance fundamental understanding and solve problems that those from a single discipline could not. Interdisciplinary mentoring teams are essential to the BIRCWH Program, and as such, an inter-professional, team-based approach for mentoring BIRCWH Scholars is expected. These teams should include mentors from diverse disciplines to carry out interdisciplinary projects.

Team members may include individuals from medical, dentistry, pharmacy, nursing, biotechnology, data science, social sciences, anthropology, genetics, and other disciplines representing different perspectives and areas of expertise. These teams come together to collaborate as a unit, with the common goal of supporting a BIRCWH Scholar in the transition from trainee to independent researcher.

In this NOFO, the interdisciplinary team approach is applied to the study of the health of women across the lifespan, bridging basic and clinical science and incorporating new models of collaboration and institutional support. Proposed Programs must ensure the integration of interdisciplinary mentoring teams.

In previously funded NIH research on causal factors and Interventions that promote and support the Careers of Women in Biomedical and Behavioral Science and Engineering findings report the importance of both mentoring teams and team science in career development. In recognition of these findings, this NOFO encourages a team science research approach as well as the utilization of interdisciplinary mentoring teams.

More information can be found in a Journal of Academic Medicine publication, http://www. ncbi. nlm.

nih. gov/pubmed/27191836 , and https://womeninscience. nih.

gov/pdfs/BestPracticesReport. pdf . See Section VIII.

Other Information for award authorities and regulations. Section II. Award Information Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.

Application Types Allowed The OER Glossary and the How to Apply - Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO. Optional: Accepting applications that either propose or do not propose clinical trial(s).

Need help determining whether you are doing a clinical trial? Funds Available and Anticipated Number of Awards The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications. Pending availability of funds, ORWH and its NIH institute, center, and office partners intend to fund between 8 to 10 awards, corresponding to a total of $7.

5 million per year, starting in Fiscal Year 2025. Future year amounts will depend on annual appropriations. Application budgets are limited to a maximum direct cost per year of $840,000 for each award.

The proposed budgets need to reflect the actual needs of the project. The maximum project period is 5 years. Other Award Budget Information Individuals designing, directing, and implementing the career development program may request salary and fringe benefits appropriate for the person months devoted to the program.

Salaries requested may not exceed the levels commensurate with the institution's policy for similar positions and may not exceed the congressionally mandated cap. If mentoring interactions and other activities with scholars are considered a regular part of an individual's academic duties, then mentoring and other interactions with scholars are non-reimbursable from grant funds.

A Research Director may be appointed to perform day-to-day administration and management of the award. This should be an experienced investigator with skills and qualifications complementing those of the PD/PI. Salary and fringe benefits for the Research Director, if any, up to 1.

2 person months may be requested. Also, salary and fringe benefits up to 6 person months effort for a program assistant may be requested; the level of effort may be adjusted. If the PD/PI elects to delegate the day-to-day administration and management of the award to a separate Research Director, then compensation will not be provided for the PD/PI.

Salary support for individuals involved in program administration and management must be substantially justified. Salary support for ancillary personnel (e.g. administrative assistance or secretarial support) on CDAs is not allowable. Scholars are those individuals who benefit from the proposed activities and experiences involved in the career development program.

Scholar costs must be justified as specifically required for the proposed career development program and based on institutional policies for salaries paid to individuals in similar positions, regardless of the source of funds. These expenses must be itemized in the proposed budget. Salary : BIRCWH Scholars’ salary and fringe support is intended to offset only that portion of the salary that is devoted to research and career development.

Each Scholar may be provided salary support up to $100,000 direct costs from NIH funds, plus fringe benefits per grantee institutional policy, annually. Research and Career Development Support : The budget must include funds for research and career development support for each BIRWCH Scholar between $25,000 and $50,000..

Research and career development costs may include the following expenses: (1) tuition and fees related to career development; (2) research expenses, such as supplies, equipment, and technical personnel; (3) travel to training or scientific meetings other than the annual BIRCWH meeting; (4) statistical services including consultant costs and computer time; and (5) other project infrastructure including relevant secondary data sets.

Patient care costs such as inpatient bed days or outpatient visits, except for clinical laboratory analyses essential for the Scholars' research, will not be supported with K12 funds. Other Program Related Expenses Shared consultant, equipment, and supply costs, travel for key persons, and other program-related expenses such as guest speaker fees and/or honoraria may be included in the proposed budget.

These expenses must be justified as specifically required by the proposed program and must not duplicate items generally available at the applicant institution. With strong justification, a shared Resource Laboratory may be requested as part of the Program, within the total budget. Such a resource must be a new entity, not an extension or enhancement of an existing facility.

The Shared Resource Laboratory might include scientific services such as, but not limited to, assays, molecular biology, or biostatistics. Requests for this Resource Laboratory must be justified in terms of cost-effective enhancement of the research resources that will serve the three BIRCWH Scholars' projects.

Travel to an annual BIRCWH meeting for the PD/PI, Research Director, and current Scholars must be requested in this application. Travel to the annual BIRCWH meeting for Scholars should not come from their research support. Travel of the PD/PI, Program Director, or program mentors to scientific meetings other than the annual BIRCWH meeting will not be supported with K12 funds.

Indirect Costs (also known as Facilities & Administrative [F&A] Costs) are reimbursed at 8% of modified total direct costs (exclusive of tuition and fees, consortium costs in excess of $25,000, and expenditures for equipment), rather than on the basis of a negotiated rate agreement. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO. Section III.

Eligibility Information Higher Education Institutions Public/State Controlled Institutions of Higher Education Private Institutions of Higher Education Nonprofits Other Than Institutions of Higher Education Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education) Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education) Indian/Native American Tribal Governments (Federally Recognized) Indian/Native American Tribal Governments (Other than Federally Recognized) U.S. Territory or Possession Native American Tribal Organizations (other than Federally recognized tribal governments) Faith-based or Community-based Organizations Eligible Agencies of the Federal Government U.S. Territory or Possession The sponsoring institution must assure support for the proposed program.

Appropriate institutional commitment to the program includes the provision of adequate staff, facilities, and educational resources that can contribute to the planned program. The applicant institution must have a strong and high quality research program in the area(s) proposed under this NOFO and must have the requisite faculty, staff, potential trainees and facilities on site to conduct the proposed institutional program.

In many cases, it is anticipated that the proposed program will complement other ongoing career development programs occurring at the applicant institution and that a substantial number of program faculty will have active research projects in which participating scholars may gain relevant experiences consistent with their research interests and goals. Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement , are not allowed. Applicant organizations must complete and maintain the following registrations as described in the How to Apply - Application Guide to be eligible to apply for or receive an award. All registrations must be completed prior to the application being submitted.

Registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible. Failure to complete registrations in advance of a due date is not a valid reason for a late submission, please reference NIH Grants Policy Statement Section 2. 3.

9. 2 Electronically Submitted Applications for additional information. System for Award Management (SAM) – Applicants must complete and maintain an active registration, which requires renewal at least annually .

The renewal process may require as much time as the initial registration. SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code. NATO Commercial and Government Entity (NCAGE) Code – Foreign organizations must obtain an NCAGE code (in lieu of a CAGE code) in order to register in SAM.

Unique Entity Identifier (UEI) – A UEI is issued as part of the SAM. gov registration process. The same UEI must be used for all registrations, as well as on the grant application.

eRA Commons – Once the unique organization identifier is established, organizations can register with eRA Commons in tandem with completing their Grants. gov registration; all registrations must be in place by time of submission. eRA Commons requires organizations to identify at least one Signing Official (SO) and at least one Program Director/Principal Investigator (PD/PI) account in order to submit an application.

Grants. gov – Applicants must have an active SAM registration in order to complete the Grants. gov registration.

Program Directors/Principal Investigators (PD(s)/PI(s)) All PD(s)/PI(s) must have an eRA Commons account. PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons. If the PD/PI is also the organizational Signing Official, they must have two distinct eRA Commons accounts, one for each role.

Obtaining an eRA Commons account can take up to 2 weeks. Eligible Individuals (Program Director/Principal Investigator) Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research training program as the Training Program Director/Principal Investigator (Training PD/PI) is invited to work with their organization to develop an application for support.

For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the How to Apply - Application Guide .

The PD/PI should be an established investigator in the scientific area in which the application is targeted and capable of providing both administrative and scientific leadership to the development and implementation of the proposed program.

The PD/PI will be responsible for the selection and appointment of trainees to the approved research training program, and for the overall direction, management, administration, and evaluation of the program. The PD/PI will be expected to monitor and assess the program and submit all documents and reports as required.

The PD/PI has responsibility for the day-to-day administration of the program and is responsible for appointing members of the Advisory Committee (when applicable), using their recommendations to determine the appropriate allotment of funds. This NOFO does not require cost sharing as defined in the NIH Grants Policy Statement Section 1. 2 Definition of Terms .

3. Additional Information on Eligibility Applicant organizations may submit more than one application, provided that each application is programmatically distinct. NIH will not accept duplicate or highly overlapping applications under review at the same time per NIH Grants Policy Statement Section 2.

3. 7. 4 Submission of Resubmission Application .

This means that the NIH will not accept: A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) or resubmission (A1) application. A resubmission (A1) application that is submitted before issuance of the summary statement from the review of the previous new (A0) application.

An application that has substantial overlap with another application pending appeal of initial peer review (see NIH Grants Policy Statement 2. 3. 9.

4 Similar, Essentially Identical, or Identical Applications ). Programs are encouraged to build a broadly diverse team of preceptors/mentors that includes, for example, faculty at different career stages (i.e., junior as well as senior faculty). Scholars to be supported by the institutional career development program must be at the career level for which the planned program is intended.

Scholars are expected to devote a minimum of 9 person-months (75% of full-time professional effort) during the appointment on the K12 award. Scholars must be citizens or noncitizen nationals of the United States or have been lawfully admitted for permanent residence at the time of appointment. Additional details on citizenship requirements are available in the NIH Grants Policy Statement .

Scholars to be supported by the institutional career development program must be at the career level for which the planned program is intended. Scholars are expected to devote a minimum of 9 person-months (75% of full-time professional effort), or at least 6 person-months for surgical specialties, during the appointment on the K12 award .

Scholars must be citizens or noncitizen nationals of the United States or have been lawfully admitted for permanent residence at the time of appointment. Additional details on citizenship requirements are available in the NIH Grants Policy Statement . At the time of appointment, BIRCWH Scholars must: Have a clinical doctorate or Ph.

D. degree or its equivalent. Have completed any postgraduate training normally expected for a faculty appointment in their field (including clinical or postdoctoral fellowship training, or residency if they have chosen not to subspecialize).

Have no more than eight years of research or research training experience beyond their last doctoral degree. Have been assigned mentors with extensive research experience relevant to the Scholars' individual research and career development goals.

Not be or have been a PD/PI on a Center (P50, P60, P20, P30, U54) grant or subproject of a Program Project (P01), individual career development (K-series) award, or independent research project grant awards (R01) or equivalent . In keeping with the type of mentoring and career development being provided by the K12, a Scholar who is competitive for P01 or R01 grant support is likely to be too senior for the BIRCWH program.

Postdoctoral trainees must have received, as of the beginning date of the NRSA appointment, a Ph. D. , M.

D. , D. D.

S. , or comparable doctoral degree from an accredited domestic or foreign institution. Comparable doctoral degrees include, but are not limited to, the following: D.

M. D. , DC, DO, DVM.

, OD, DPM, ScD, EngD, DrPH, DNSc, DPT, PharmD, ND (Doctor of Naturopathy), DSW, PsyD, as well as a doctoral degree in nursing research. Documentation by an authorized official of the degree-granting institution certifying all degree requirements have been met prior to the beginning date of the training appointment is acceptable.

Individuals in postgraduate clinical training, who wish to interrupt their studies for a year or more to engage in full-time research training before completing their formal training programs, are also eligible. Section IV. Application and Submission Information 1.

Requesting an Application Package The application forms package specific to this opportunity must be accessed through ASSIST, Grants. gov Workspace or an institutional system-to-system solution. Links to apply using ASSIST or Grants.

gov Workspace are available in Part 1 of this NOFO. See your administrative office for instructions if you plan to use an institutional system-to-system solution. 2.

Content and Form of Application Submission It is critical that applicants follow the Training (T) Instructions in the How to Apply - Application Guide except where instructed in this notice of funding opportunity to do otherwise. Conformance to the requirements in the How to Apply - Application Guide is required and strictly enforced.

Applications that are out of compliance with these instructions may be delayed or not accepted for review. Although a letter of intent is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows IC staff to estimate the potential review workload and plan the review. By the date listed in Part 1.

Overview Information, prospective applicants are asked to submit a letter of intent that includes the following information: Descriptive title of proposed activity Name(s), address(es), and telephone number(s) of the PD(s)/PI(s) Names of other key personnel Participating institution(s) Number and title of this funding opportunity The letter of intent should be sent to: Office of Research on Women's Health (ORWH) All page limitations described in the How to Apply - Application Guide and the Table of Page Limits must be followed.

Instructions for Application Submission The following section supplements the instructions found in the How to Apply - Application Guide and should be used for preparing an application to this NOFO. Substitute the term “scholars” for all references to “trainees” in the SF424 (R&R) Application Guide, and substitute the term “career development” for all references to “training” in the SF424 (R&R) Application Guide.

All instructions in the How to Apply - Application Guide must be followed. SF424(R&R) Project/Performance Site Locations All instructions in the How to Apply - Application Guide must be followed. SF424 (R&R) Other Project Information All instructions in the How to Apply - Application Guide must be followed.

Substitute the term “scholars” for all references to “trainees” in the How to Apply - Application Guide , and substitute the term “career development” for all references to “training” in the How to Apply - Application Guide . Project Summary/Abstract. Provide an abstract of the entire application.

Include the objectives, rationale and design of the career development program, as well as key activities in the training plan.

Indicate the planned duration of appointments, the projected number of scholars including their levels (i.e., predoctoral , postdoctoral , short-term faculty ), and intended trainee/scholar outcomes The filename provided for each “Other Attachment” will be the name used for the bookmark in the electronic application in eRA Commons.

SF424(R&R) Senior/Key Person Profile Expanded Follow all instructions provided in the How to Apply - Application Guide . PHS 398 Cover Page Supplement Follow all instructions provided in the How to Apply - Application Guide . PHS 398 Training Subaward Budget Attachment(s) Follow all instructions provided in the How to Apply - Application Guide .

Research and Related (R&R) Budget Follow all instructions provided in the How to Apply - Application Guide with the following additional modifications: Include all personnel other than the Training PD(s)/PI(s) in the Other Personnel section, including clerical and administrative staff. Also include proposed salary costs for planned scholars. Do not complete the section on Participant/Trainee Support Costs.

PHS 398 Research Training Program Plan The PHS 398 Research Training Program Plan Form is comprised of the following sections: Faculty, Trainees, and Training Record Other Training Program Sections Appendix- Note that the Appendix should only be used in circumstances covered in the NIH policy on appendix materials or if the NOFO specifically instructs applicants to do so Other Plans -- Priority areas or restrictions from the ORWH and its sponsoring institutes, centers, or offices.

Follow all instructions provided in the How to Apply - Application Guide . Particular attention must be given to the required Training Data Tables . Data Tables 1, 2, 4, 6B, 7, 8C are required for this application; No other Data Tables may be submitted.

Applicants should summarize, in the body of the application, key data from the tables that highlight the characteristics of the applicant pool, faculty mentors, the educational and career outcomes of past participants, and other factors that contribute to the overall environment of the program.

Please note that the race, ethnicity, or sex of scholar applicants, past program participants, or faculty mentors will not be considered in the application review process or when making funding decisions.

Office of Research on Women's Health (ORWH) In terms of advancing career development, the research areas may encompass the etiology, pathogenesis and/or new treatments, diseases and conditions that affect women including studies on the various manifestations of disease.

Research to improve the health of women needs comprehensive consideration of the many factors that influence women’s health, such as sex, race and ethnicity, and a host of other internal and external factors. Moreover, it is critical to consider these factors and their potential interactions across the life course.

The overall themes of proposed research projects, and associated cores must inform the etiology, pathogenesis and/or treatment of a condition underlying women's health. Areas of Interest of Participating Institutes, Centers, and Offices (ICOs) While applications submitted in