NIH IMPROVE Initiative: Maternal Health Technology & Digital Care SBIR Funding Opportunity is sponsored by National Institutes of Health (NIH) - Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). This opportunity supports mission-aligned projects and measurable outcomes.

NIH IMPROVE Initiative: Maternal Health Technology & Digital Care SBIR Funding Opportunity — BW&CO NIH Highlighted Topic: Enhancing the IMPROVE-funded Maternal Health Centers of Excellence Below is a brief summary. Please check the full solicitation before applying (link in resources section).

The National Institutes of Health (NIH) is encouraging supplemental research proposals that enhance and expand the IMPROVE-funded Maternal Health Research Centers of Excellence and Hubs. This highlighted topic supports projects designed to accelerate research and innovation aimed at reducing maternal morbidity and mortality, particularly in underserved regions and populations with disproportionately poor maternal health outcomes.

The initiative is part of the NIH Implementing a Maternal Health and Pregnancy Outcomes Vision for Everyone (IMPROVE) Initiative and seeks to strengthen ongoing maternal health research through expanded geographic reach, collaborative partnerships, and integration of emerging maternal health technologies.

NIH is especially interested in projects that expand research into maternity care deserts and regions with high rates of maternal mortality and severe maternal morbidity.

Companies developing maternal health technologies, remote patient monitoring systems, digital health platforms, AI-enabled maternal risk prediction tools, telehealth infrastructure, wearable devices, pregnancy monitoring technologies, clinical analytics systems, or healthcare coordination platforms may be strong candidates for funding.

Areas of interest include maternal mortality prevention, pregnancy-related complication monitoring, rural and underserved healthcare delivery, collaborative maternal health research networks, digital diagnostics, remote monitoring, and integration of technologies developed through the RADx maternal health challenge.

NIH is also encouraging scalable technologies and interventions that improve maternal outcomes, access to care, and longitudinal pregnancy health monitoring. Funding is available through the NIH SBIR/STTR Program and related NIH supplemental funding mechanisms, with opportunities for both translational research and commercialization support depending on project scope and alignment with existing IMPROVE-funded Centers and Hubs.

This highlighted topic is supported primarily by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), which is seeking transformative innovations that improve maternal healthcare access, clinical outcomes, and implementation of advanced maternal health technologies. How much funding would I receive?

Awards provide up to $323,090 for Phase I projects (up to 2 years) and $2,153,927 for Phase II projects (up to 3 years). Some topics approved by NIH may exceed these limits. Fast-Track and Phase IIB (follow-on) options allow continuous or extended funding beyond Phase II.

What could I use the funding for? Funding may support the research, development, validation, implementation, and commercialization of maternal health technologies, remote monitoring systems, clinical analytics platforms, and healthcare delivery solutions designed to reduce maternal morbidity and mortality.

Eligible activities may include: Remote maternal monitoring and wearable pregnancy technologies AI and machine learning platforms for maternal risk prediction Telehealth systems for prenatal and postpartum care Digital diagnostics and point-of-care maternal health technologies Healthcare coordination and maternal care navigation platforms Expansion of maternal health programs into maternity care deserts Pregnancy complication monitoring and early warning systems Clinical decision support systems for maternal healthcare providers Integration of RADx maternal health technologies into care delivery Population health analytics and maternal outcomes tracking systems Community-based maternal health intervention technologies Longitudinal pregnancy and postpartum monitoring platforms Rural maternal healthcare access and infrastructure technologies Collaborative maternal health data-sharing and interoperability systems Equity-focused maternal health implementation and outreach platforms Prototype development, implementation studies, and translational research Commercialization planning, regulatory preparation, and scale-up activities Funding may also support personnel, software engineering, cloud infrastructure, AI model development, wearable integration, clinical validation studies, telehealth deployment, healthcare systems integration, community engagement, intellectual property protection, regulatory strategy, and commercialization activities necessary to advance a scalable and commercially viable maternal health solution aligned with NIH priorities.

Are there any additional benefits I would receive? Beyond the formal funding award, awardees gain several strategic advantages: Government Validation and Credibility: Being selected for an NIH-backed SBIR grant signals technical excellence and alignment with national health and biomedical priorities. This validation builds investor and partner confidence.

Enhanced Visibility and Market Recognition: Awardees are featured in NIH and HHS announcements, helping attract partnerships, media attention, and future contracting opportunities. Access to the Federal Innovation Ecosystem: Recipients join a national network of researchers and agencies advancing life science innovation, often opening doors to collaborations with NIH laboratories and federal health programs.

Stronger Commercial and Exit Potential: By maturing technology through nondilutive funding, companies strengthen valuation, de-risk commercialization, and increase attractiveness for acquisition or follow-on private investment. What is the timeline to apply and when would I receive funding? Applications are accepted each year on January 5th, April 5th, and September 5th.

Funding is received approximately 9 months after submission. Where does this funding come from? Funding comes from the U.S. Department of Health and Human Services , with statutory set-asides requiring NIH, CDC, and FDA to devote portions of their extramural R&D budgets (3.

2% for SBIR, 0. 45% for STTR) to support small business innovation. Who is eligible to apply?

Applicants must be U.S. small business concerns (SBCs) that: Are organized for profit with a U.S. place of business. Have ≤ 500 employees including affiliates. Are > 50% owned by U.S. citizens or permanent residents, qualifying U.S. entities, or combinations thereof.

What companies and projects are likely to win? Projects that demonstrate: A clear unmet medical or public-health need , Strong scientific rationale and feasibility , High commercialization potential , supported by a realistic market and regulatory strategy, and Alignment with an NIH Institute’s or CDC/FDA Center’s specific research mission (e.g., infectious disease, digital health, diagnostics, therapeutics, or data analytics).

Competitive applicants often have an early prototype, preliminary data, and a defined path to market adoption. Are there any restrictions I should know about? Companies must complete multiple federal registrations ( SAM.

gov , Grants. gov , eRA Commons, SBA Company Registry) before applying. Foreign entities are not eligible .

Disclosure of foreign affiliations and compliance with national security screening are mandatory. Currently we do not recommend any sort of foreign affiliation. How long will it take me to prepare an application?

For a first-time applicant , preparing a competitive submission will likely take 120–200 hours in total.

Our team specializes in complex federal R&D proposals and can: Triple your likelihood of success through proven strategy and insider-aligned proposal development Reduce your time spent on the proposal by 50–80% , letting your team focus on technology and operations Ensure you are targeting the best opportunity for your project and positioning your company for long-term growth. Review solicitation here.

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