NIH Science Education Partnership Award (SEPA) (R25) is a grant from the National Institutes of Health (NIH) that funds research education programs designed to encourage students to pursue careers in biomedical research and the life sciences. Supported activities include curriculum development, skills development courses, and science education partnerships that align with NIH's mission of advancing health-related research.

The program is co-sponsored by numerous NIH institutes and centers, including NIGMS, NIAID, NIMH, and others, reflecting its broad biomedical scope. Eligible applicants include 501(c)(3) nonprofit organizations, higher education institutions, and independent school districts. Awards are up to $250,000 per year.

The current announcement deadline is May 25, 2026.

Expired PAR-23-137: NIH Science Education Partnership Award (SEPA) (R25 - Clinical Trial Not Allowed) This notice has expired. For NIH, in limited situations, applications may be accepted on a case-by-case basis for a short period after expiration to accommodate NIH late or continuous submission policies . Contact the eRA Service Desk for any submission issues.

Check the NIH Guide for active opportunities and notices. Part 1.

Overview Information Participating Organization(s) National Institutes of Health ( NIH ) Components of Participating Organizations National Institute of General Medical Sciences ( NIGMS ) National Eye Institute ( NEI ) National Human Genome Research Institute ( NHGRI ) National Institute on Alcohol Abuse and Alcoholism ( NIAAA ) National Institute of Allergy and Infectious Diseases ( NIAID ) National Institute of Arthritis and Musculoskeletal and Skin Diseases ( NIAMS ) National Institute of Biomedical Imaging and Bioengineering ( NIBIB ) Eunice Kennedy Shriver National Institute of Child Health and Human Development ( NICHD ) National Institute of Dental and Craniofacial Research ( NIDCR ) National Institute of Diabetes and Digestive and Kidney Diseases ( NIDDK ) National Institute on Drug Abuse ( NIDA ) National Institute of Mental Health ( NIMH ) National Institute of Neurological Disorders and National Institute of Nursing Research ( NINR ) National Institute on Minority Health and Health Disparities ( NIMHD ) National Center for Complementary and Integrative Health ( NCCIH ) Office of The Director, National Institutes of Health ( OD ) All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers.

The following NIH Offices may co-fund applications assigned to those Institutes/Centers. Office of Research on Women's Health ( ORWH ) Office of Data Science Strategy ( ODSS ) NIH BRAIN Initiative ( https://braininitiative. nih.

gov/ ) Funding Opportunity Title NIH Science Education Partnership Award (SEPA) (R25 - Clinical Trial Not Allowed) April 04, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025. See Notice NOT-OD-24-084 November 8, 2023 - Notice of NINRs Scientific Interests for PAR-23-137, NIH Science Education Partnership Award (SEPA) (R25 - Clinical Trial Not Allowed).

See Notice NOT-NR-24-002 NOT-OD-22-195 - New NIH "FORMS-H" Grant Application Forms and Instructions Coming for Due Dates on or after January 25, 2023 NOT-OD-19-109 - Requirement for ORCID iDs for Individuals Supported by Research Training, Fellowship, Research Education, and Career Development Awards Beginning in FY 2020.

NOT-OD-23-012 - Reminder: FORMS-H Grant Application Forms & Instructions Must be Used for Due Dates On or After January 25, 2023 - New Grant Application Instructions Now Available Notice of Funding Opportunity (NOFO) Number Companion Funding Opportunity See Section III. 3. Additional Information on Eligibility.

Assistance Listing Number(s) 93. 859, 93. 307, 93.

855, 93. 273, 93. 866, 93.

313, 93. 865, 93. 310, 93.

846, 93. 361, 93. 213, 93.

242, 93. 853, 93. 847, 93.

867, 93. 279, 93. 121, 93.

286 Funding Opportunity Purpose The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that encourage individuals to pursue further studies or careers in biomedical research.

To accomplish the stated over-arching goal, this NOFO will support educational activities with a primary focus on: Courses for Skills Development Curriculum or Methods Development Open Date (Earliest Submission Date) Letter of Intent Due Date(s) Renewal / Resubmission / Revision (as allowed) All applications are due by 5:00 PM local time of applicant organization.

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Required Application Instructions It is critical that applicants follow the instructions in the Research (R) Instructions in the SF424 (R&R) Application Guide , except where instructed to do otherwise (in this NOFO or in a Notice from NIH Guide for Grants and Contracts ). Conformance to all requirements (both in the Application Guide and the NOFO) is required and strictly enforced.

Applicants must read and follow all application instructions in the Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions. Applications that do not comply with these instructions may be delayed or not accepted for review.

Part 1. Overview Information Part 2. Full Text of Announcement Section I.

Funding Opportunity Description Section II. Award Information Other Award Budget Information Section III. Eligibility Information Section V.

Application Review Information Section VI. Award Administration Information Section VII. Agency Contacts Section VIII.

Other Information Part 2. Full Text of Announcement Section I. Funding Opportunity Description The NIH Research Education Program (R25) supports research educational activities that complement other formal training programs in the mission areas of the NIH Institutes and Centers.

The NIH Research Education Program (R25) supports research education activities that complement other formal training programs in the mission areas of the NIH. The overarching goal of the NIGMS Science Education Partnership Award (SEPA) R25 program is to support educational activities that encourage pre-college students (pre-kindergarten to grade 12).

SEPA supports two types of projects: (1) classroom-based projects for pre-kindergarten to grade 12 (pre-college) students and teachers and (2) informal science education (ISE) projects conducted in outside-the-classroom venues such as science centers, museums and libraries. Projects that support quantitative and computational skills development are strongly encouraged.

A SEPA project may focus on one or more of the following activities centered on any discipline of health research within NIH’s mission: Courses for Skills Development: Courses in a specific discipline or research area that extend the STEM content normally taught in schools. Research Experiences: Hands-on exposure to research for pre-college students and teachers.

Mentoring Activities: Provide participants with a perspective on the biomedical research training pathways and tools for overcoming challenges, navigating career transition points, and successfully transitioning into careers in the biomedical research workforce.

Curriculum or Methods Development: STEM education resources to improve biomedical, behavioral or clinical science education, or develop novel instructional approaches or computer-based educational tools. Outreach: Dissemination of STEM education resources or biomedical, behavioral and clinical research findings to students, teachers and the general public. Examples of SEPA projects can be found at https://nigms.

nih. gov/capacity-building/division-for-research-capacity-building/science-education-partnership-awards-(sepa) . Applicants are strongly encouraged to consult with the appropriate Scientific/Research Contact listed in Section VII.

Agency Contacts. See Section VIII. Other Information for award authorities and regulations.

Section II. Award Information Grant: A support mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity. Application Types Allowed The OER Glossary and the SF424 (R&R) Application Guide provide details on these application types.

Only those application types listed here are allowed for this NOFO. Not Allowed: Only accepting applications that do not propose clinical trial(s). Need help determining whether you are doing a clinical trial?

Funds Available and Anticipated Number of Awards The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications. Direct costs are limited to $250,000, excluding consortium F&A costs, annually. The scope of the proposed project should determine the project period.

The maximum project period is 5 years. Other Award Budget Information Individuals designing, directing, and implementing the research education program may request salary and fringe benefits appropriate for the person months devoted to the program. Salaries requested may not exceed the levels commensurate with the institution's policy for similar positions and may not exceed the congressionally mandated cap.

(If mentoring interactions and other activities with participants are considered a regular part of an individual's academic duties, then any costs associated with the mentoring and other interactions with participants are not allowable costs from grant funds). Participants for this NOFO are those individuals who are involved in the proposed research education activity.

Participants may be paid if specifically required for the proposed research education program and sufficiently justified. Participant costs must be itemized in the proposed budget. Other Program-Related Expenses Consultant costs, equipment, supplies, travel for key persons, and other program-related expenses may be included in the proposed budget.

These expenses must be justified as specifically required by the proposed program and must not duplicate items generally available at the applicant institution. Funds may be requested for the PD(s)/PI(s) and other key personnel to attend the annual SEPA Conference. A maximum of ten percent (10%) of the direct costs requested may be devoted to evaluation-related activities.

Indirect Costs (also known as Facilities & Administrative [F&A] Costs) are reimbursed at 8% of modified total direct costs (exclusive of tuition and fees, expenditures for equipment and consortium costs in excess of $25,000), rather than on the basis of a negotiated rate agreement. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO. Section III.

Eligibility Information Higher Education Institutions Public/State Controlled Institutions of Higher Education Private Institutions of Higher Education Nonprofits Other Than Institutions of Higher Education Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education) Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education) For-Profit Organizations (Other than Small Businesses) City or Township Governments Special District Governments Indian/Native American Tribal Governments (Federally Recognized) Indian/Native American Tribal Governments (Other than Federally Recognized) Eligible Agencies of the Federal Government U.S. Territory or Possession Independent School Districts Public Housing Authorities/Indian Housing Authorities Native American Tribal Organizations (other than Federally recognized tribal governments) Faith-based or Community-based Organizations Public, Private and Charter schools The applicant institution must assure support for the proposed program.

Appropriate institutional commitment to the program includes the provision of adequate staff, facilities, and educational resources that can contribute to the planned program. Institutions with existing Ruth L.

Kirschstein National Research Service Award (NRSA) institutional training grants (e.g., T32) or other Federally funded training programs may apply for a research education grant provided that the proposed educational experiences are distinct from those training programs receiving federal support.

In many cases, it is anticipated that the proposed research education program will complement ongoing research training occurring at the applicant institution. Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement , are not allowed.

Applicant organizations must complete and maintain the following registrations as described in the SF 424 (R&R) Application Guide to be eligible to apply for or receive an award. All registrations must be completed prior to the application being submitted. Registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible.

The NIH Policy on Late Submission of Grant Applications states that failure to complete registrations in advance of a due date is not a valid reason for a late submission. System for Award Management (SAM) Applicants must complete and maintain an active registration, which requires renewal at least annually . The renewal process may require as much time as the initial registration.

SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code. NATO Commercial and Government Entity (NCAGE) Code Foreign organizations must obtain an NCAGE code (in lieu of a CAGE code) in order to register in SAM. Unique Entity Identifier (UEI) A UEI is issued as part of the SAM.

gov registration process. The same UEI must be used for all registrations, as well as on the grant application. eRA Commons - Once the unique organization identifier is established, organizations can register with eRA Commons in tandem with completing their Grants.

gov registration; all registrations must be in place by time of submission. eRA Commons requires organizations to identify at least one Signing Official (SO) and at least one Program Director/Principal Investigator (PD/PI) account in order to submit an application. Grants.

gov Applicants must have an active SAM registration in order to complete the Grants. gov registration. Program Directors/Principal Investigators (PD(s)/PI(s)) All PD(s)/PI(s) must have an eRA Commons account.

PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons. If the PD/PI is also the organizational Signing Official, they must have two distinct eRA Commons accounts, one for each role. Obtaining an eRA Commons account can take up to 2 weeks.

Eligible Individuals (Program Director/Principal Investigator) Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with their organization to develop an application for support.

For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the SF424 (R&R) Application Guide. The PD(s)/PI(s) should have the appropriate expertise and experience to provide both administrative and scientific leadership to the development and implementation of the proposed project.

The PD(s)/PI(s) will be expected to monitor and assess the program and submit all documents and reports as required. This NOFO does not require cost sharing as defined in the NIH Grants Policy Statement . 3.

Additional Information on Eligibility Applicant organizations may submit more than one application, provided that each application is scientifically distinct. The NIH will not accept duplicate or highly overlapping applications under review at the same time per 2. 3.

7. 4 Submission of Resubmission Application. This means that the NIH will not accept: A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) application.

An application that has substantial overlap with another application pending appeal of initial peer review. Additional Eligibility Information: A PD/PI with an active SEPA award is eligible to submit a new SEPA application as long as the new SEPA project is distinct from the active project and there is no more than six months overlap between the end date of the current SEPA award and the potential start date of the new SEPA award.

An institution with an active SEPA award, i.e., within the 5-year project start and end dates, is eligible to submit new applications in a different scientific discipline distinct from the active SEPA project.

Organizations with a contractual fee for service or consortium partnership with an active SEPA award may submit a SEPA application if the proposed new project is independent of the existing SEPA contractual fee for service or consortium partnership. Program faculty and mentors should have research expertise and experience relevant to the proposed program.

Participants in SEPA programs are pre-college students, teachers or the general public. Unless strongly justified on the basis of exceptional relevance to NIH, research education programs should be used primarily for the education of U.S. citizens and permanent residents. Section IV.

Application and Submission Information 1. Requesting an Application Package The application forms package specific to this opportunity must be accessed through ASSIST, Grants. gov Workspace or an institutional system-to-system solution.

Links to apply using ASSIST or Grants. gov Workspace are available in Part 1 of this NOFO. See your administrative office for instructions if you plan to use an institutional system-to-system solution.

2. Content and Form of Application Submission It is critical that applicants follow the instructions in the Research (R) Instructions in the SF424 (R&R) Application Guide , except where instructed in this Notice of Funding Opportunity to do otherwise. Conformance to the requirements in the Application Guide is required and strictly enforced.

Applications that are out of compliance with these instructions will not be reviewed. All page limitations described in the SF424 Application Guide and the Table of Page Limits must be followed. Instructions for Application Submission The following section supplements the instructions found in the SF424 (R&R) Application Guide and should be used for preparing an application to this NOFO.

Follow all instructions provided in the SF424 (R&R) Application Guide. SF424(R&R) Project/Performance Site Locations Follow all instructions provided in the SF424 (R&R) Application Guide. SF424(R&R) Other Project Information Component Follow all instructions provided in the SF424 (R&R) Application Guide with the following additional modifications: Facilities & Other Resources.

Describe the educational environment, including the facilities, laboratories, participating departments, computer services, and any other resources to be used in the development and implementation of the proposed program. List all thematically related sources of support for research training and education following the format for Current and Pending Support.

SF424(R&R) Senior/Key Person Profile Expanded Follow all instructions provided in the SF424 (R&R) Application Guide. An evaluator must be listed in the Key Personnel section. Follow all instructions provided in the SF424 (R&R) Application Guide with the following additional modifications: Include all personnel other than the PD(s)/PI(s) in the Other Personnel section, including clerical and administrative staff.

The PD/PI must devote a minimum of 2. 0 person months per year. Up to 4.

8 person months PD/PI effort per year can be requested with justification. In the case of multiple PD/PI (MPI) projects, each PD/PI must devote a minimum of 2. 0 person months per year.

Up to 4. 8 person months per year can be requested for the combined MPI effort. Use the section on Participant/Trainee Support Costs to request support for participants in the program.

PHS 398 Cover Page Supplement Follow all instructions provided in the SF424 (R&R) Application Guide.

All instructions in the SF424 (R&R) Application Guide must be followed, with the following additional instructions: The Research Strategy section must be used to upload the Research Education Program Plan , which must include the following components described below: Proposed Research Education Program Program Director(s)/Principal Investigator(s) Institutional Environment and Commitment Plan for Instruction in the Responsible Conduct of Research Research Education Program Plan Proposed Research Education Program.

While the proposed research education program may complement ongoing research training and education occurring at the applicant institution, the proposed educational experiences must be distinct from those research training and research education programs currently receiving federal support.

When research training programs are on-going in the same department, the applicant organization should clearly distinguish between the activities in the proposed research education program and the research training supported by the training program. The Proposed Research Education Plan should address the following: Clear goals and anticipated outcomes.

A Gantt Chart that visualizes overall project plan, timelines and the relationship between various activities. Project alignment with the practices, crosscutting concepts, and core ideas of the Next Generation Science Standards (NGSS) . How the Logic Model depicts the relationship between your program’s activities and its intended effects.

Strategies to develop critical thinking skills. Relevance to the target audience(s). Input from the students, teachers, community and other stakeholders.

Potential to build a sustainable STEM education capacity for the community. Potential for replication or adaptation at different locations)or institutions. If an advisory committee is proposed, discuss the composition, roles and responsibilities of the committee, desired expertise of committee members, and frequency of committee meetings.

Describe how the advisory committee will monitor progress and advise the project team on the overall effectiveness of the program. Advisory committee members should not be identified or contacted prior to receiving an award.

Applicants who have had a prior SEPA award, or an active SEPA project that is ending before the next funding cycle, are strongly encouraged to utilize their SEPA-generated infrastructure, partnerships, and evaluation tools for the new SEPA project. Program Director/Principal Investigator. Describe arrangements for the administration of the program.

Provide evidence that the Program Director/Principal Investigator is actively engaged in research and/or teaching in an area related to the mission of NIH, and can organize, administer, monitor, and evaluate the research education program. For programs proposing multiple PDs/PIs, describe the complementary and integrated expertise of the PDs/PIs, their leadership approach, and governance appropriate for the planned project.

Program Faculty. SEPA faculty are the individuals who assist the PD/PI to design and deliver the education activities and/or mentor participants. Faculty should have expertise relevant to the proposed program and a demonstrated history of, or the potential for, their intended roles.

Near Peer Mentors . How the role models or near-peer mentors will be selected and trained must be described in the application. Project Evaluator.

Document that the evaluator is free of actual or perceived conflict of interest and has expertise relevant to the participants, grade level; and project format (classroom-based, out-of-classroom, science center or library). Program Participants. Applicants must describe the intended participants, including the rationale for their participation and grade level(s).

Institutional Environment and Commitment. Describe any additional aspects of the Institutional Environment and Commitment not addressed under Facilities & Other Resources or the required Institutional Commitment Letter of Support, described below. Appropriate institutional commitment should include the provision of adequate staff, facilities, and educational resources that can contribute to the planned research education program.

This section should not duplicate information provided elsewhere. Plan for Instruction in the Responsible Conduct of Research. All applications must include a plan to fulfill NIH requirements for instruction in the Responsible Conduct of Research (RCR).

The plan must address the five, required instructional components outlined in the NIH policy: 1) Format - the required format of instruction, i.e., face-to-face lectures, coursework, and/or real-time discussion groups (a plan with only non-interactive instruction is not acceptable); 2) Subject Matter - the breadth of subject matter, e.g., conflict of interest, authorship, data management, human subjects and animal use, laboratory safety, research misconduct, research ethics; 3) Faculty Participation - the role of the program faculty in the instruction; 4) Duration of Instruction - the number of contact hours of instruction, taking into consideration the duration of the program; and 5) Frequency of Instruction instruction must occur during each career stage and at least once every four years.

See also NOT-OD-10-019 and NOT-OD-22-055 . The plan should be appropriate and reasonable for the nature and duration of the proposed program. Renewal (Type 2) applications must, in addition, describe any changes in formal instruction over the past project period and plans to address any weaknesses in the current instruction plan.

All participating faculty who served as course directors, speakers, lecturers, and/or discussion leaders during the past project period must be named in the application. Projects proposing a student or teacher laboratory internships component must include participant training plans to improve the culture and practice of laboratory safety through the implementation of best safety practices in the laboratory .

Applications lacking a plan for instruction in responsible conduct of research will not be reviewed. Evaluation Plan. Applications must include a plan for evaluating the activities supported by the award.

The application must specify baseline metrics (e.g., numbers, educational levels, and aggregate demographic characteristics of participants), as well as measures to gauge the short- or long-term success of the research education award in achieving its objectives. Wherever appropriate, applicants are encouraged to obtain feedback from participants to help identify weaknesses and to provide suggestions for improvements.

If appropriate, the evaluator may provide training as necessary to key personnel to ensure the integrity and adequacy of data capture, analysis and reporting. Statistically rigorous evaluation designs such as Randomized Controlled Trial (RCT) and Well-Matched Comparison (WMCC), etc., are encouraged to be used to evaluate classroom-based projects to allow strong conclusions about effectiveness. Dissemination Plan.

A plan must be provided describing how findings resulting from or materials developed under the auspices of the research education program will be disseminated nationally, e.g., sharing course curricula and related materials via web postings, presentations at scientific meetings, workshops. The Dissemination Plan should provide access to STEM resources by Limited English Proficient Persons (LEP).

SEPA projects must include a project website development plan for dissemination of resources developed. The website may be a new website or a SEPA-specific component added to an existing website. The SEPA website must be launched within 6 months from the initial award date.

Credit text for NIH, NIGMS and SEPA must be displayed on the website Home Page and cited in publications generated by SEPA support. The website must be free and open to the public. A letter of institutional commitment must be attached as part of Letters of Support (see section above: Institutional Environment and Commitment.

Institutional letters of support and commitment should include a discussion on the provision of adequate staff, facilities, and educational resources that can contribute to the planned research education program. Applicants are encouraged to include 1-page letters of support, appropriate for the proposed SEPA project, from key personnel, collaborators, and other significant partners, stakeholders and contributors.

Note: Effective for due dates on or after January 25, 2023, a Data Management and Sharing Plan is not applicable for this NOFO. Individuals are required to comply with the instructions for the Resource Sharing Plans as provided in the SF424 (R&R) Application Guide. Appendix: Only limited Appendix materials are allowed.

Follow the instructions for the Appendix as described in the SF424 (R&R) Application Guide.

PHS Human Subjects and Clinical Trials Information When involving human subjects research, clinical research, and/or NIH-defined clinical trials (and when applicable, clinical trials research experience) follow all instructions for the PHS Human Subjects and Clinical Trials Information form in the SF424 (R&R) Application Guide, with the following additional instructions: If you answered Yes to the question Are Human Subjects Involved?

on the R&R Other Project Information form, you must include at least one human subjects study record using the Study Record: PHS Human Subjects and Clinical Trials Information form or Delayed Onset Study record. Study Record: PHS Human Subjects and Clinical Trials Information All instructions in the SF424 (R&R) Application Guide must be followed.

Note: Delayed onset does NOT apply to a study that can be described but will not start immediately (i.e., delayed start). All instructions in the SF424 (R&R) Application Guide must be followed. PHS Assignment Request Form All instructions in the SF424 (R&R) Application Guide must be followed.

3. Unique Entity Identifier and System for Award Management (SAM) See Part 1. Section III.

1 for information regarding the requirement for obtaining a unique entity identifier and for completing and maintaining active registrations in System for Award Management (SAM), NATO Commercial and Government Entity (NCAGE) Code (if applicable), eRA Commons, and Grants. gov 4. Submission Dates and Times Part I.

Overview Information contains information about Key Dates and times. Applicants are encouraged to submit applications before the due date to ensure they have time to make any application corrections that might be necessary for successful submission. When a submission date falls on a weekend or Federal holiday , the application deadline is automatically extended to the next business day.

Organizations must submit applications to Grants. gov (the online portal to find and apply for grants across all Federal agencies). Applicants must then complete the submission process by tracking the status of the application in the eRA Commons , NIH’s electronic system for grants administration.

NIH and Grants. gov systems check the application against many of the application instructions upon submission. Errors must be corrected and a changed/corrected application must be submitted to Grants.

gov on or before the application due date and time. If a Changed/Corrected application is submitted after the deadline, the application will be considered late. Applications that miss the due date and time are subjected to the NIH Policy on Late Application Submission.

Applicants are responsible for viewing their application before the due date in the eRA Commons to ensure accurate and successful submission. Information on the submission process and a definition of on-time submission are provided in the SF424 (R&R) Application Guide. 5.

Intergovernmental Review (E. O. 12372) This initiative is not subject to intergovernmental review .

All NIH awards are subject to the terms and conditions, cost principles, and other considerations described in the NIH Grants Policy Statement . Pre-award costs are allowable only as described in the NIH Grants Policy Statement . 7.

Other Submission Requirements and Information Applications must be submitted electronically following the instructions described in the SF424 (R&R) Application Guide. Paper applications will not be accepted. Applicants must complete all required registrations before the application due date.

Section III. Eligibility Information contains information about registration. For assistance with your electronic application or for more information on the electronic submission process, visit How to Apply Application Guide .

If you encounter a system issue beyond your control that threatens your ability to complete the submission process on-time, you must follow the Dealing with System Issues guidance. For assistance with application submission, contact the Application Submission Contacts in Section VII. All PD(s)/PI(s) must include their eRA Commons ID in the Credential field of the Senior/Key Person Profile form .

Failure to register in the Commons and to include a valid PD/PI Commons ID in the credential field will prevent the successful submission of an electronic application to NIH. The applicant organization must ensure that the unique entity identifier provided on the application is the same identifier used in the organization’s profile in the eRA Commons and for the System for Award Management.

Additional information may be found in the SF424 (R&R) Application Guide. See more tips for avoiding common errors. Upon receipt, applications will be evaluated for completeness and compliance with application instructions by the Center for Scientific Review and NIGMS.

Applications that are incomplete or non-compliant will not be reviewed. Hyperlinks and URLs are not permitted by this NOFO in Specific Aims, Research Strategy and other page-limited attachments. Please follow specific instructions included in NOT-OD-20-174 .

Post Submission Materials Applicants are required to follow the instructions for post-submission materials, as described in the policy . Section V. Application Review Information Only the review criteria described below will be considered in the review process.

Applications submitted to the NIH in support of the NIH mission are evaluated for scientific and technical merit through the NIH peer review system. For this particular announcement, note the following: The goal of this R25 program is to support innovative, high-quality skills development, mentoring, and outreach educational activities that encourage pre-college students to pursue further studies in STEM fields.

Reviewers will provide an overall impact score to reflect their assessment of the likelihood for the project to strongly advance research education by fulfilling the goal of this R25 Education Program, in consideration of the following review criteria