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Find similar grantsRolling; consult NSF 24-539 and PAPPG for specific due dates
NSF Systems and Synthetic Biology Cluster is sponsored by National Science Foundation (NSF). Supports fundamental research in systems biology and synthetic biology approaches addressing questions in molecular and cellular biology, including immune system research.
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Systems and Synthetic Biology | NSF - U.S. National Science Foundation Division of Molecular and Cellular Biosciences Core Programs (MCB) Systems and Synthetic Biology NSF's implementation of the revised 2 CFR NSF Financial Assistance awards (grants and cooperative agreements) made on or after October 1, 2024, will be subject to the applicable set of award conditions, dated October 1, 2024, available on the NSF website .
These terms and conditions are consistent with the revised guidance specified in the OMB Guidance for Federal Financial Assistance published in the Federal Register on April 22, 2024.
Important information for proposers All proposals must be submitted in accordance with the requirements specified in this funding opportunity and in the NSF Proposal & Award Policies & Procedures Guide (PAPPG) that is in effect for the relevant due date to which the proposal is being submitted. It is the responsibility of the proposer to ensure that the proposal meets these requirements.
Submitting a proposal prior to a specified deadline does not negate this requirement.
Updates to NSF Research Security Policies On July 10, 2025, NSF issued an Important Notice providing updates to the agency's research security policies, including a research security training requirement, Malign Foreign Talent Recruitment Program annual certification requirement, prohibition on Confucius institutes and an updated FFDR reporting and submission timeline.
Supports research that employs systems biology or synthetic biology approaches to address compelling questions in molecular and cellular biology. Tool development to advance systems and synthetic biology is also supported. Supports research that employs systems biology or synthetic biology approaches to address compelling questions in molecular and cellular biology.
Tool development to advance systems and synthetic biology is also supported. NSF BIO supports proposals that use systems and/or synthetic biology to understand molecular or cellular mechanisms. It also seeks projects that advance systems or synthetic biology as disciplines.
A high priority is given to research that reveals the molecular or cellular underpinnings of complex behavior and emergent properties. Projects that synergistically combine experimental investigations with computational approaches or mathematical modeling are encouraged.
The following are research areas of interest: Molecular to system-wide events that drive the assembly, function, and emergent properties of natural and synthetic microbial communities Synthetic cells, synthetic cell components, and cell-like systems that mimic biological functions Origins of life and the minimal cell Synthetic systems that explore biological diversity beyond that encountered in nature Synthetic systems that make use of epigenetic regulation Biological information storage and processing Integration of multi-omics data sets to obtain mechanistic insights Mechanistic modeling of all levels of gene regulatory control, signaling and metabolic networks, and interactions among networks Development of novel experimental, computational, or mathematical tools to discover and explore fundamental molecular-scale mechanisms Awards made through this program Browse projects funded by this program Map of recent awards made through this program Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (BIO/MCB)
Based on current listing details, eligibility includes: Applicants must consult the full solicitation NSF 24-539 and PAPPG for eligibility; program supports systems and synthetic biology research addressing molecular and cellular biology questions. Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates $100,000-$500,000+ Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
The current target date is rolling deadlines or periodic funding windows. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.
Federal grant success rates typically range from 10-30%, varying by agency and program. Build a strong proposal with clear objectives, measurable outcomes, and a well-justified budget to improve your chances.
Requirements vary by sponsor, but typically include a project narrative, budget justification, organizational capability statement, and key personnel CVs. Check the official notice for the complete list of required attachments.
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Many federal programs offer multi-year funding or allow competitive renewals. Check the official solicitation for continuation and renewal policies. Non-competing continuation applications are common for multi-year awards.
NSF Small Business Innovation Research / Small Business Technology Transfer Phase I Programs (SBIR/STTR Phase I) is sponsored by U.S. National Science Foundation (NSF). The NSF SBIR/STTR programs provide non-dilutive funds for use-inspired research and development (R&D) of unproven, leading-edge, technology innovations that address societal challenges. These programs fund broadly across scientific and engineering disciplines.
Small Business Innovation Research / Small Business Technology Transfer Phase I Programs (SBIR/STTR Phase I) is sponsored by National Science Foundation (NSF). America's Seed Fund, powered by NSF, supports startups with research and development funding for unproven, leading-edge technology innovations that address societal challenges. This program broadly funds scientific and engineering disciplines. Specific sub-topics under 'Agricultural Technologies' include Food Waste Mitigation, Resilient Supply & Distribution, and 'Chemical Technologies' includes Food Processing, Chemicals and Agriculture, making it highly relevant for food and beverage technology, especially consumer app development related to these areas.