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Open Philanthropy's landmark Technical AI Safety Research RFP is one of the largest dedicated funding programs for AI safety research, committing approximately $40 million across 21 research directions organized into five clusters.
The clusters include: (1) Adversarial Machine Learning — jailbreak detection, control evaluations, and alignment stress tests; (2) Sophisticated Misbehavior — alignment faking, deceptive behavior, and hidden capability detection; (3) Model Transparency — interpretability applications, activation monitoring, and feature discovery; (4) Trust from First Principles — rare misbehavior estimation and theoretical inductive biases; (5) Alternative Approaches — conceptual clarity on AGI risks and novel alignment agendas.
The application process begins with a streamlined 300-word Expression of Interest (EOI), with responses within two weeks. Promising EOIs are invited to submit full proposals, with funding decisions approximately two months later. The program explicitly supports research on large language models or work with transferable insights to LLMs.
Administered through Coefficient Giving, the fund draws on contributions from Good Ventures and over 20 additional philanthropists.
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Search similar grants →Based on current listing details, eligibility includes: Researchers at any career stage including graduate students, faculty, and independent researchers. Academic institutions, nonprofit organizations, and non-academic research groups eligible. Multiple EOIs per applicant allowed. Projects must study LLMs or have transferable insights to LLMs. Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates Funding amounts vary based on project scope and sponsor guidance. Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
The current target date is July 15, 2025. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.
The Wellcome Trust funds research applying generative AI to mental health, specifically anxiety disorders, depressive disorders, and psychotic disorders. Awards of up to £3 million (approximately USD $3.8 million) support up to 2 years of research following a 4-month accelerator stage. The program supports two research areas: (1) creating or improving generative AI models for mental health measurement and intervention, and (2) generating evidence on safe collaboration between generative models, mental health professionals, and people with lived experience. The program explicitly does not fund real-world deployment or broader population applications, focusing instead on fundamental research. Teams receive accelerator support before the full grant phase.
The Coefficient Giving AI Governance RFP funds research and projects addressing catastrophic risks from advanced AI through governance mechanisms. The program supports six primary subject areas: (1) Technical AI governance including compute governance, model evaluations, and standards development; (2) Policy development for AI regulation and oversight; (3) Frontier company policies to improve internal safety and governance practices; (4) International AI governance frameworks and cooperation; (5) Legal frameworks for AI accountability and liability; and (6) Strategic analysis and threat modeling of AI risks. Funded activities include research projects, training and mentorship programs, general organizational support, and other innovative projects. The program is open to applicants worldwide from academia, nonprofits, industry, and independent researchers. While the January 2026 deadline has passed, Coefficient Giving has indicated that future AI governance RFPs are likely as they continue proactive grantmaking in this area. The fund draws on contributions from Good Ventures and over 20 philanthropists.
The Cleveland Clinic – Denmark: Quantum-AI Biomedical Frontiers Fellowship Programme 2026 is a joint initiative of the Novo Nordisk Foundation and Cleveland Clinic that supports postdoctoral researchers combining quantum technologies and artificial intelligence with biomedical and clinical applications. Each fellowship provides up to DKK 3.6 million (approximately $500,000 USD) over a three-year project period, with DKK 1.2 million annually. The total programme allocates DKK 43 million (~$6.2 million) to support 12 exchange researchers, each receiving a three-year term to conduct high-level research either at Cleveland Clinic in the United States or at Danish institutions. Fellows explore how quantum computing can enhance AI models for drug discovery, medical imaging, genomics, and personalized medicine. The programme includes an optional one-year return phase. Results are announced in June 2026. This is part of the Novo Nordisk Foundation's broader Quantum Computing Programme, which invests significantly in quantum technologies and their applications to life sciences.