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PROactive Solutions for Prolonging Resilience (PROSPR) program is sponsored by Advanced Research Projects Agency for Health (ARPA-H), U.S. Department of Health and Human Services (HHS). The PROSPR program funds research teams to develop tools and therapies aimed at extending healthspan by detecting and intervening on the earliest changes associated with aging.
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Proactive Solutions for Prolonging Resilience What if we had therapies to extend healthspan and prevent the onset of age-related diseases? Despite recent increases in average lifespan across the U.S., there has not been a corresponding increase in healthspan – the amount of time a person remains in good health and free from long-term disease or disability.
Currently, 80% of all adults over the age of 65 have at least one chronic condition, and 30% of the same population are considered “pre-frail,” which is associated with a higher risk of mortality in the next five years. Americans with symptoms of aging such as fatigue, reduced cognitive ability, pain, reduced hearing and vision, and sleep disruption have very few treatment options.
With this aging demographic expected to only increase, health care costs will rise significantly. In response to these issues, the PROactive Solutions for Prolonging Resilience (PROSPR) program aims to identify biochemical and physiological markers and develop assessment tools that will allow researchers to better understand and target the underlying causes of age-related disease.
To achieve this goal, PROSPR will pioneer in-home data collection and clinical trial protocols that can assess age-associated health outcomes in just three years instead of decades of study, accelerating the availability of new therapies. If successful, PROSPR will build a new therapeutic industry with interventions focused on maintaining health during aging.
A revolutionary approach to extending the healthspan of people across the U.S. requires a comfort with calculated research that only a funding agency such as ARPA-H can provide. Research teams to add more healthy years to Americans’ lives as they age ARPA-H launches new program aimed at extending the healthspan of Americans
According to the current listing, eligibility includes: Research teams, including universities and biomedical research organizations. Awards are contracts contingent upon meeting research milestones. Confirm the full requirements in the official notice before applying.
The current listing shows up to $144 million over five years (total program investment), individual contracts vary. Verify award ceilings, matching requirements, and allowable costs in the official notice.
PROactive Solutions for Prolonging Resilience (PROSPR) program is funded by Advanced Research Projects Agency for Health (ARPA-H), U.S. Department of Health and Human Services (HHS). Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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