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The Alfred P. Sloan Foundation's Exploratory Grantmaking in Technology program, with a dedicated AI in Science track, supports the development and adoption of AI tools that accelerate scientific research and automate aspects of the scientific process.
Funded scope includes foundation models for science (chemistry, biology, materials, physics), AI lab automation and self-driving laboratories, AI-driven literature review and synthesis tools, machine learning for experimental design, scientific reasoning and hypothesis generation in LLMs, infrastructure for open scientific AI, reproducibility and transparency of machine learning in research, and the philosophy of science applied to ML.
Rolling letters of inquiry are accepted year-round with a deadline of December 31, 2026 for the current cycle. Letters of inquiry are reviewed quarterly. Sloan is particularly interested in open-science orientation and replicable AI infrastructure for scientific discovery.
Strong fit for U.S. universities, research institutes, and nonprofits building open foundation models for science, autonomous lab software, AI-driven scientific reasoning, or open scientific AI benchmarks.
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org * Click to expand this navigation menu Research * History of Science and Technology * Sloan Digital Sky Survey * Small-Scale Fundamental Physics * Click to expand this navigation menu Technology * Exploratory Grantmaking in Technology * Scientific Collaboration * Click to expand this navigation menu Public Understanding * Click to expand this navigation menu Completed Programs * Anytime, Anyplace Learning * Better Software for Science * Chemistry of Indoor Environments * Data & Computational Research * Deep Carbon Observatory * Information about Careers in Science and Technology * Making Municipal Governments More Responsive * Microbiology of the Built Environment * Professional Science Master's Degree * Scholarly Communication * Universal Access to Knowledge * Workplace, Workforce, and Working Families Sloan Research Fellowships * Commitment to Opportunity for All * Click to expand this navigation menu Press Room
According to the current listing, eligibility includes: U.S.-based universities, research institutes, nonprofits, and qualified individuals affiliated with such institutions. Open-science / open-access orientation strongly favored. International collaborators allowed as part of U.S.-led projects. Confirm the full requirements in the official notice before applying.
The current listing shows grants typically range from $100,000 to $400,000 per project. Larger awards possible for high-impact infrastructure or multi-institution proposals. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Applications for Alfred P Sloan Foundation Exploratory Grantmaking in Technology AI in Science Program for Foundation Models for Science Lab Automation and Scientific Reasoning are due January 1, 2027. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
Alfred P Sloan Foundation Exploratory Grantmaking in Technology AI in Science Program for Foundation Models for Science Lab Automation and Scientific Reasoning is funded by Alfred P. Sloan Foundation. Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.