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Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs (General solicitations) is sponsored by National Institutes of Health (NIH). NIH offers congressionally mandated set-aside programs for U.S. small businesses to engage in research and development activities with strong potential for commercialization.
Applicants propose investigator-initiated ideas via parent grant announcements or respond to specific funding opportunities focused on particular research areas.
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U.S. Department of Health and Human Services National Institutes of Health The SBIR and STTR programs were reauthorized on April 13, 2026. Currently, NIH has no active SBIR or STTR Notices of Funding Opportunity (NOFOs). Future NOFOs are forecasted at Grants.
gov prior to opening for applications. The next standard receipt date is September 5, 2026. Learn if your company is eligible for NIH SBIR or STTR funding, how to apply , and what to expect during each step of the application process.
Multiple registrations are required to prepare your application and apply for funding.
Small Business Program Basics Understanding SBIR and STTR Foreign Disclosure and Risk Management SBIR and STTR Grants (NOFO s ) SBIR Contract Solicitations Commercialization Readiness Pilot (CRP) Small Business Transition Grant for New Entrepreneurs Navigate NIH's Research Areas Applicant Assistance Programs --> Transition Award (Coming Soon) Our team can help you maximize the benefits from NIH programs and resources which help you bring your innovations to life.
NIH's Technical and Business Assistance (TABA) Concept to Clinic Commercializing Innovation (C3i) The NIH is actively turning discovery into health by helping small businesses develop innovative technologies that improve health and save lives. See how .
Small Business Portfolio Overview Active Small Business Awards Research Evaluation and Commercialization Hubs (REACH) Search Technologies from Academic Centers and Hubs Our team can help you maximize the benefits from NIH programs and resources which help you bring your innovations to life. We value biomedical innovation and strive to empower scientists and entrepreneurs to bring their discoveries to patients.
HHS Small Business Program Managers Non-dilutive funding for early-stage research and development. [ Parent Announcements ] [ Specific Opportunities ] More information on HHS SBIR contracts is available on the NIH SBIR contracts webpage . NIH has committed $20 million to support academic product development and innovation.
Learn more about the five new Research Evaluation and Commercialization Hubs (REACH) in the funding opportunity announcement (RFA-OD-23-005) Standard Application Due Dates are September 5, January 5, and April 5. Due dates that fall on weekends or Federal holidays are moved to the next business day. Some SBIR/STTR grant solicitations are focused on specific research areas.
Some specific NOFOs, identified as RFAs (Requests for Applications) or PASs (Program Announcements with Set-aside funds), have funding set-aside in the Institute/Center's budget for that targeted program. National Institutes of Health Product Development Support Looking for the NIH SBIR & STTR site? The new seed.
nih. gov has everything you’re looking for about the NIH small business research and development programs (SBIR & STTR) . In addition, you can learn about other types of product development and commercialization support for NIH award recipients .
Questions? Check out About the NIH SEED Office or email us at [email protected] .
Based on current listing details, eligibility includes: U.S. small businesses (fewer than 500 employees, for-profit, majority-owned by U.S. citizens or permanent residents). Projects must align with NIH's mission and research interests. Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates Phase I typically up to $275,000; Phase II up to $1.8 million; some topics allow for higher amounts. See official notice. Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
The current target date is rolling deadlines or periodic funding windows. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.
Federal grant success rates typically range from 10-30%, varying by agency and program. Build a strong proposal with clear objectives, measurable outcomes, and a well-justified budget to improve your chances.
Requirements vary by sponsor, but typically include a project narrative, budget justification, organizational capability statement, and key personnel CVs. Check the official notice for the complete list of required attachments.
Yes — AI tools like Granted can help research funders, draft proposal sections, and check compliance. However, always review and customize AI-generated content to reflect your organization's unique strengths and the specific requirements of the solicitation.
Review timelines vary by funder. Federal agencies typically take 3-6 months from submission to award notification. Foundation grants may be faster, often 1-3 months. Check the program's timeline in the official solicitation for specific dates.
Many federal programs offer multi-year funding or allow competitive renewals. Check the official solicitation for continuation and renewal policies. Non-competing continuation applications are common for multi-year awards.
Past winners and funding trends for this program
Accelerating Solutions to Improve Access and Quality of Empirically-Supported Practices for Youth Mental Health (R01 Clinical Trial Optional) is sponsored by National Institutes of Health (NIH). This NOFO encourages research that studies methods to increase access to evidence-based interventions and services for youth mental health, particularly for those in rural, inner-city, and under-resourced areas, and youth experiencing homelessness. It addresses optimizing assessment, intervention, and service strategies, workforce shortages, waitlists, and integrating treatment and prevention into settings like schools, social services, pediatric medicine, and justice systems.
PHS 2024-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required) is sponsored by National Institutes of Health (NIH) and Centers for Disease Control and Prevention (CDC). This omnibus solicitation supports small businesses in developing promising technologies and products that align with the mission of NIH and CDC to improve health and save lives, specifically for applications that include clinical trials.