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Small Business Innovation Research (SBIR) - Digital Health (DH) is sponsored by National Science Foundation (NSF). This program supports entrepreneurs and startups developing innovative, differentiated, and novel technologies to improve physical or mental well-being or health, enable or assist individuals to increase or regain independence and quality of life, and improve healthcare delivery.
Technologies applying AI in healthcare, assistive technologies for aging or disabled populations, and rehabilitative technologies are within scope.
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Digital Health Grant – Apply Today | NSF SBIR Check recent critical alerts! (Last updated 12/22/2025) NSF has temporarily paused the submission of new Project Pitches to the SBIR/STTR programs due to the lapse in congressional authorization. Program Directors will continue to process Project Pitches that were previously received.
Please direct any questions to sbir@nsf. gov . The Neural Analytics Lucid™ M1 transcranial Doppler Ultrasound System is indicated as an adjunct to the standard clinical practices for measuring and displaying cerebral blood flow velocity within the major conducting arteries and veins of the head and neck.
Additionally, the Lucid™ M1 System measures the occurrence of transient emboli signals within the blood stream.
The Digital Health topic aims to support entrepreneurs and startups at the earliest-stages of development of innovative, differentiated and novel technologies that aim to improve physical or mental wellbeing or health, enable or assist individuals to increase or regain independence and quality of life and improve the delivery of healthcare including efficiency, reducing cost or improving outcomes.
Technologies in this portfolio include those applying AI in healthcare or general wellness (medical image analysis, personalized medicine, EHR/EMR, Clinical decision support, Computer aided diagnostics, support or therapy, smart/connected medical devices) as well as technologies that enable or provide assistance to aging or disabled populations and individuals undergoing rehabilitation. DH1.
Assistive, Enabling and Rehabilitative technologies DH2. AI in healthcare and drug discovery DH3. Healthcare Workflow, Economics and Delivery DH4.
Medical Diagnostics and Devices DH5. Physical, Mental and Behavioral Health DH6. Other Digital Health Technologies Application process for Digital Health (DH) funding Eligibility for Digital Health (DH) funding + Your company must be a small business (fewer than 500 employees) located in the United States.
At least 50% of your company’s equity must be owned by U.S. citizens or permanent residents. NSF does not fund companies that are majority-owned by multiple venture capital firms, private equity firms, or hedge funds, to participate in SBIR and STTR. All funded work, including work done by consultants and contractors, needs to take place in the United States.
The project’s principal investigator (tech lead) must be legally employed at least 20 hours a week by the company seeking funding. The principal investigator doesn’t need any advanced degrees. The principal investigator needs to commit to at least one month (173 hours) of work on a funded project per six months of project duration.
Evaluation Criteria: What We Look for When Evaluating Digital Health (DH) proposals + Take our project assessment to see if your work might be a good fit for NSF funding.
'Moxi' the robot that supports nurses Diligent Robotics, a small business funded by the National Science Foundation (NSF), created “Moxi,” a robot that supports clinical staff teams in acute care hospitals by executing logistical tasks so staff can focus on direct human care. To learn more visit: https://diligentrobots. com/ We invest up to $2 million in seed funding and take zero equity.
We’re looking for companies that are transformative, high-risk, have a market pull, and are scaleable.
Key questions and narrative sections extracted from the solicitation.
Project description (10–15 pages addressing innovation, technical approach, and R&D plan)
Commercialization strategy
Scoring criteria used to review proposals for this grant.
Based on current listing details, eligibility includes: U.S.-based small businesses (fewer than 500 employees) with at least 50% equity owned by U.S. citizens or permanent residents. All funded work must take place in the United States. Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates Not specified (NSF funds startups, generally provides early-stage R&D grants) Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
The current target date is rolling deadlines or periodic funding windows. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.
Federal grant success rates typically range from 10-30%, varying by agency and program. Build a strong proposal with clear objectives, measurable outcomes, and a well-justified budget to improve your chances.
Requirements vary by sponsor, but typically include a project narrative, budget justification, organizational capability statement, and key personnel CVs. Check the official notice for the complete list of required attachments.
Yes — AI tools like Granted can help research funders, draft proposal sections, and check compliance. However, always review and customize AI-generated content to reflect your organization's unique strengths and the specific requirements of the solicitation.
Review timelines vary by funder. Federal agencies typically take 3-6 months from submission to award notification. Foundation grants may be faster, often 1-3 months. Check the program's timeline in the official solicitation for specific dates.
Many federal programs offer multi-year funding or allow competitive renewals. Check the official solicitation for continuation and renewal policies. Non-competing continuation applications are common for multi-year awards.
Past winners and funding trends for this program
Improving Undergraduate STEM Education: Education & Human Resources (IUSE: EHR) Program is sponsored by National Science Foundation (NSF). This program promotes novel, creative, and transformative approaches to generating and using new knowledge about STEM teaching and learning to improve STEM education for undergraduate students. It supports projects that bring recent advances in STEM knowledge into undergraduate education, adapt, improve, and incorporate evidence-based practices, and lay the groundwork for institutional improvement in STEM education. Professional development for instructors to ensure adoption of new and effective pedagogical techniques is a potential topic of interest.
Small Business Innovation Research (SBIR)/Small Business Technology Transfer (STTR) Phase I (NSF 24-579) is sponsored by National Science Foundation (NSF). This program provides non-dilutive funds for use-inspired research and development (R&D) of unproven, leading-edge technology innovations that address societal challenges. Small businesses must first submit a Project Pitch and receive an official invitation to submit a full proposal. The maximum award amount has been increased to $305,000, and the award duration is 6-18 months.
NSF Small Business Innovation Research / Small Business Technology Transfer Phase I Programs is sponsored by National Science Foundation (NSF). These programs provide non-dilutive funds for use-inspired research and development of unproven, leading-edge technology innovations that address societal challenges. NSF funds broadly across scientific and engineering disciplines and does not solicit specific technologies.
Note: Each funding opportunity description is a synopsis of information in the Federal Register application notice. For specific information about eligibility, please see the official application notice. The official version of this document is the document published in the Federal Register. Free Internet access to the official edition of the Federal Register and the Code of Federal Regulations is available on GPO Access at: http://www.access.gpo.gov/nara/index.html. Please review the official application notice for pre-application and application requirements, application submission information, performance measures, priorities and program contact information. Purpose of Program: The purpose of this program is to stimulate technological innovation in the private sector, strengthen the role of small business in meeting Federal research or research and development (R/R&D) needs, increase the commercial application of the U.S. Department of Education (Department) supported research results, and improve the return on investment from federally funded research for economic and social benefits to the Nation. Catalog of Federal Domestic Assistance (CFDA) Number: 84.133S-1. If you choose to submit your application electronically, you must use the Governmentwide Grants.gov Apply site at http://www.Grants.gov. Through this site, you will be able to download a copy of the application package, complete it offline, and then upload and submit your application. You may not e-mail an electronic copy of a grant application to us. You may access the electronic grant application for the SBIR Program at: http://www.Grants.gov. You must search for the downloadable application package for this competition by the CFDA number. Do not include the CFDA number's alpha suffix in your search (e.g. , search for 84.133, not 84.133S). The telephone number for the Grants.gov Helpdesk is 1-800-518-4726 or e-mail: support@grants.gov. Funding Opportunity Number: ED-GRANTS-090908-001. Assistance Listing: 84.133. Funding Instrument: G. Category: ED. Award Amount: Up to $75K per award.
NIST invites applications for a program involving technical and business engagement activities directed at small businesses participating in NISTs Small Business Innovation Research Program. The TCAP recipient will provide NIST SBIR Phase I and/or Phase II recipients with technical and business expertise and resources to identify optimum pathways to promote successful transition of the Phase I and/or Phase II results to commercialization. Funding Opportunity Number: 2014-NIST-SBIR-02. Assistance Listing: 11.620. Funding Instrument: CA. Category: ST.
This Funding Opportunity Announcement (FOA) invites Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) for funding to perform research leading to the development of innovative technologies that may advance progress for early detection and assessment of individuals at risk and for early diagnosis, prognosis and follow-up of type 1 diabetes (T1D). Funding Opportunity Number: RFA-DK-15-024. Assistance Listing: 93.847. Funding Instrument: G. Category: FN,HL. Award Amount: $2M total program funding.