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Small Business Innovation Research (SBIR) Program is sponsored by National Institutes of Health (NIH), referenced through the National Institute of Justice (NIJ). This federal grant initiative provides non-dilutive funding to small businesses for early-stage research and development of innovative technologies that can be commercialized and improve public safety, health, and other priority areas.
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U.S. Department of Health and Human Services National Institutes of Health Learn if your company is eligible for NIH SBIR or STTR funding, how to apply , and what to expect during each step of the application process. Multiple registrations are required to prepare your application and apply for funding.
Small Business Program Basics Understanding SBIR and STTR Foreign Disclosure and Risk Management SBIR and STTR Grants (NOFO s ) SBIR Contract Solicitations Commercialization Readiness Pilot (CRP) Small Business Transition Grant for New Entrepreneurs Navigate NIH's Research Areas Applicant Assistance Programs --> Transition Award (Coming Soon) Our team can help you maximize the benefits from NIH programs and resources which help you bring your innovations to life.
NIH's Technical and Business Assistance (TABA) Concept to Clinic Commercializing Innovation (C3i) The NIH is actively turning discovery into health by helping small businesses develop innovative technologies that improve health and save lives. See how .
Small Business Portfolio Overview Active Small Business Awards Research Evaluation and Commercialization Hubs (REACH) Search Technologies from Academic Centers and Hubs Our team can help you maximize the benefits from NIH programs and resources which help you bring your innovations to life. We value biomedical innovation and strive to empower scientists and entrepreneurs to bring their discoveries to patients.
HHS Small Business Program Managers Non-dilutive funding for early-stage research and development. [ Parent Announcements ] [ Specific Opportunities ] More information on HHS SBIR contracts is available on the NIH SBIR contracts webpage . NIH has committed $20 million to support academic product development and innovation.
Learn more about the five new Research Evaluation and Commercialization Hubs (REACH) in the funding opportunity announcement (RFA-OD-23-005) Standard Application Due Dates are September 5, January 5, and April 5. Due dates that fall on weekends or Federal holidays are moved to the next business day.
NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional) NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional) NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional) Some SBIR/STTR grant solicitations are focused on specific research areas.
Some specific NOFOs, identified as RFAs (Requests for Applications) or PASs (Program Announcements with Set-aside funds), have funding set-aside in the Institute/Center's budget for that targeted program. National Institutes of Health Product Development Support Looking for the NIH SBIR & STTR site? The new seed.
nih. gov has everything you’re looking for about the NIH small business research and development programs (SBIR & STTR) . In addition, you can learn about other types of product development and commercialization support for NIH award recipients .
Questions? Check out About the NIH SEED Office or email us at [email protected] .
According to the current listing, eligibility includes: Eligible U. S. small businesses. Multiple registrations are required to prepare and apply for funding. Confirm the full requirements in the official notice before applying.
The current listing shows varies by phase (e.g., Phase I typically up to $175,000, Phase II typically up to $1,000,000). Verify award ceilings, matching requirements, and allowable costs in the official notice.
Applications for Small Business Innovation Research (SBIR) Program are due September 5, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
Small Business Innovation Research (SBIR) Program is funded by National Institutes of Health (NIH), referenced through the National Institute of Justice (NIJ). Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly.
Small Business Innovation Research (SBIR) / Small Business Technology Transfer (STTR) Programs (Phase I) is sponsored by U.S. Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA). The USDA SBIR/STTR programs focus on transforming scientific discovery into products and services with commercial potential and/or societal benefit in agriculturally-related areas. This can include app development for agricultural technology, rural development, and smart farming. Phase I aims to demonstrate technical feasibility.
Developer Grants is sponsored by Circle. Circle's Developer Grant initiative supports projects leveraging USDC to create practical solutions. While the 2025 applications are closed for reimagining, they will place greater emphasis on Arc-specific grants and evaluate projects based on alignment with Circle products, team strength, innovation, and impact on the USDC network in 2026.
PAR-26-042 funds NLM-priority clinical informatics R01 grants up to $250,000 in direct costs per year through March 6, 2029, with standard NIH cycles on October 5, February 5, and June 5. The notice explicitly defines non-responsive applications: incremental tool improvements, projects primarily focused on social determinants of health, and projects primarily focused on ethical/legal/social issues. With NIH SBIR/STTR just reopened and the OMB Uniform Grants Regulation rewrite reshaping discretionary awards, the NLM clinical informatics line is one of the few stable, well-defined biomedical funding streams left at the agency. Here is how to read it.
Read articleNIH's accelerating use of multiyear-funded grants — 601 awards worth $402 million in the first half of FY26, against just 146 awards worth $75 million in the same window of FY24 — has produced a fiscal contraction at research universities that has begun cascading into PhD admissions. AAU member institutions are admitting smaller graduate cohorts than they did in 2024 or 2025, with downstream consequences for the biomedical workforce, lab continuity, and the foreign-student pipeline through 2030. Why the contraction is structural rather than cyclical, and what universities, PIs, and prospective trainees should be doing in the second half of 2026.
Read articleA former 22-year NIH program officer found 205 of 336 listed funding forecasts had blown past their promised posting dates with no announcement ever published. Combined with a 54 percent year-over-year drop in competitive awards, the picture is of a science funding shutdown executed through bureaucratic delay rather than budget cuts.
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