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Find similar grantsSmall Business Innovation Research (SBIR) Program Phase II is sponsored by National Science Foundation (NSF). Provides funding for small businesses to commercialize innovative technologies, including AI solutions in healthcare and optometry.
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NSF Small Business Innovation Research / Small Business Technology Transfer Phase II Programs (SBIR/STTR Phase II) | NSF - U.S. National Science Foundation NSF Small Business Innovation Research / Small Business Technology Transfer Phase II Programs (SBIR/STTR Phase II) NSF's implementation of the revised 2 CFR NSF Financial Assistance awards (grants and cooperative agreements) made on or after October 1, 2024, will be subject to the applicable set of award conditions, dated October 1, 2024, available on the NSF website .
These terms and conditions are consistent with the revised guidance specified in the OMB Guidance for Federal Financial Assistance published in the Federal Register on April 22, 2024.
Important information for proposers All proposals must be submitted in accordance with the requirements specified in this funding opportunity and in the NSF Proposal & Award Policies & Procedures Guide (PAPPG) that is in effect for the relevant due date to which the proposal is being submitted. It is the responsibility of the proposer to ensure that the proposal meets these requirements.
Submitting a proposal prior to a specified deadline does not negate this requirement.
Updates to NSF Research Security Policies On July 10, 2025, NSF issued an Important Notice providing updates to the agency's research security policies, including a research security training requirement, Malign Foreign Talent Recruitment Program annual certification requirement, prohibition on Confucius institutes and an updated FFDR reporting and submission timeline.
Supports startups and small businesses to transform scientific discovery into products and services with commercial and societal impact. Phase II funding goes to further the development of a proof-of-concept or prototype created with Phase I funding. Supports startups and small businesses to transform scientific discovery into products and services with commercial and societal impact.
Phase II funding goes to further the development of a proof-of-concept or prototype created with Phase I funding. The NSF SBIR/STTR programs support moving scientific excellence and technological innovation from the lab to the market.
By funding startups and small businesses, NSF helps build a strong national economy and stimulates the creation of novel products, services, and solutions in private, public, or government sectors with potential for broad impact; strengthens the role of small business in meeting federal research and development needs; increases the commercial application of federally supported research results; and develops and expands the US workforce, especially by fostering and encouraging participation by socially and economically disadvantaged and women-owned small businesses.
The NSF SBIR/STTR Phase II programs provide non-dilutive funding for the development of a broad range of technologies based on discoveries in science and engineering with potential for societal and economic impacts.
Unlike fundamental or basic research activities that focus on scientific and engineering discovery itself, the NSF SBIR/STTR programs support the creation of opportunities to move use-inspired and translational discoveries out of the lab and into the market or other use at scale, through startups and small businesses. The NSF SBIR/STTR programs do not solicit specific technologies or procure goods and services.
The funding provided is non-dilutive. Any invention conceived or reduced to practice with the assistance of SBIR/STTR funding is subject to the Bayh/Dole Act. For more information, refer to Frequently Asked Questions (FAQs) , #75.
NSF encourages input and participation from the full spectrum of diverse talent that society has to offer which includes underrepresented and underserved communities. NSF seeks unproven, leading-edge, technology innovations that demonstrate the following characteristics: The innovations are underpinned and enabled by a new scientific discovery or meaningful engineering innovation.
The innovations still require intensive technical research and development to be fully embedded in a reliable product or service. The innovations have not yet been reduced to practice by anyone and it is not guaranteed, at present, that doing so is technically possible. The innovations provide a strong competitive advantage that are not easily replicable by competitors (even technically proficient ones).
Once reduced to practice, the innovations are expected to result in a product or service that would either be disruptive to existing markets or create new markets/new market segments.
The NSF SBIR/STTR programs focus on stimulating technical innovation from diverse entrepreneurs and start-ups and small businesses by translating new scientific and engineering concepts into products and services that can be scaled and commercialized into sustainable businesses with significant societal benefits.
The program provides non-dilutive funding for research and development (R&D) of use-inspired scientific and engineering activities for startups and small businesses. In Phase I, the emphasis is on de-risking those aspects preventing the innovation from reaching technical feasibility and driving the intended impact.
In Phase II, R&D continues, but the emphasis starts to shift away from research and to development challenges which, if solved, would result in new sustainable competitive advantages to allow the company to differentiate itself and drive new value propositions to the market and society. This NSF program is governed by 15 USC 638 and the National Science Foundation Act of 1950, as amended ( 42 USC §1861, et seq. ).
Introduction to the Program The SBIR and STTR programs were established in 1982 as part of the Small Business Innovation Development Act.
The NSF SBIR/STTR programs focus on stimulating technical innovation from diverse entrepreneurs and startups by translating new scientific and engineering discoveries emerging from the private sector, federal labs, and academia into products and services that can be scaled and commercialized into sustainable businesses with significant societal benefits.
The NSF SBIR/STTR programs are now part of the Directorate for Technology, Innovation and Partnerships (TIP) , which was recently launched to accelerate innovation and enhance economic competitiveness by catalyzing partnerships and investments that strengthen the links between fundamental research and technology development, deployment, and use.
Since all NSF Phase II SBIR/STTR proposers are already associated with an NSF SBIR/STTR Phase I award, Phase II proposers are strongly encouraged to use their cognizant NSF SBIR/STTR Phase I Program Officer as the primary point of contact for any questions. The contact above can be used for other inquiries, or when proposers are not sure who to contact. Please note that the following information is current at the time of publishing.
See program website for any updates to the points of contact Contact Your Phase I Program Officer September 27, 2022 - Intro to NSF’s Directorate for Technology, Innovation and… Additional program resources NSF SBIR/STTR Seed Fund Site Awards made through this program Browse projects funded by this program Map of recent awards made through this program Directorate for Technology, Innovation and Partnerships (TIP) Division of Translational Impacts (TIP/TI)
Based on current listing details, eligibility includes: Small businesses that successfully completed Phase I. Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates $1,000,000 Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
The current target date is rolling deadlines or periodic funding windows. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.
Federal grant success rates typically range from 10-30%, varying by agency and program. Build a strong proposal with clear objectives, measurable outcomes, and a well-justified budget to improve your chances.
Requirements vary by sponsor, but typically include a project narrative, budget justification, organizational capability statement, and key personnel CVs. Check the official notice for the complete list of required attachments.
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Review timelines vary by funder. Federal agencies typically take 3-6 months from submission to award notification. Foundation grants may be faster, often 1-3 months. Check the program's timeline in the official solicitation for specific dates.
Many federal programs offer multi-year funding or allow competitive renewals. Check the official solicitation for continuation and renewal policies. Non-competing continuation applications are common for multi-year awards.