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Small Business Transition Grant for New Entrepreneurs is a program from the National Institutes of Health (NIH) that supports small businesses that are new to NIH SBIR/STTR funding in developing innovative biomedical or health-related products and technologies. The program is designed to help for-profit, U.S.-owned small businesses navigate NIH's research funding landscape and maximize benefits from SBIR and STTR programs.
NIH's Technical and Business Assistance (TABA) resources and partnering opportunities are available to support applicants. Note: NIH currently has no active SBIR/STTR Notices of Funding Opportunity due to a lapse in congressional authorization; future NOFOs will be forecasted at Grants. gov prior to opening.
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Small Business Transition Grant | Seed U.S. Department of Health and Human Services National Institutes of Health NIH has no active Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) Notices of Funding Opportunity (NOFOs); therefore, there is no April 5, 2026 receipt date (see NOT-OD-26-006 ). Any future NOFOs will be forecasted at Grants. gov prior to opening for applications.
Learn if your company is eligible for NIH SBIR or STTR funding, how to apply , and what to expect during each step of the application process. Multiple registrations are required to prepare your application and apply for funding.
Small Business Program Basics Understanding SBIR and STTR Foreign Disclosure and Risk Management SBIR and STTR Grants (NOFO s ) SBIR Contract Solicitations Commercialization Readiness Pilot (CRP) Small Business Transition Grant for New Entrepreneurs Navigate NIH's Research Areas Applicant Assistance Programs --> Transition Award (Coming Soon) Our team can help you maximize the benefits from NIH programs and resources which help you bring your innovations to life.
NIH's Technical and Business Assistance (TABA) Partnering & Investment Opportunities Concept to Clinic Commercializing Innovation (C3i) The NIH is actively turning discovery into health by helping small businesses develop innovative technologies that improve health and save lives. See how .
Small Business Portfolio Overview Active Small Business Awards Research Evaluation and Commercialization Hubs (REACH) Search Technologies from Academic Centers and Hubs Our team can help you maximize the benefits from NIH programs and resources which help you bring your innovations to life. We value biomedical innovation and strive to empower scientists and entrepreneurs to bring their discoveries to patients.
HHS Small Business Program Managers Small Business Transition Grant Optimal Program Directors/Principal Investigators (PDs/PIs) for this award are early-career scientists and professionals with research, technology development, and/or healthcare delivery skills and experience, but limited entrepreneurial and independent (non-mentored) research leadership experience.
NIH is committed to diversifying the entrepreneurial workforce and encourages applications from individuals who offer unique and/or underrepresented perspectives that enrich the biomedical innovation pipeline.
Award Types: Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) , Phase I and Fast-Track Eligibility: PDs/PIs must have never been an independent PD/PI on a major research grant and must be a U.S. Citizen or Lawful Permanent Resident Mentor(s): Applicants must identify mentor(s) to: Provide technical and commercial guidance to advance the proposed research project Support preparing and executing a career development plan to successfully navigate the entrepreneurial process, develop and commercialize products, or operate a small business Due Dates: September 5, January 5, and April 5 (or the next business day, if falling on a weekend or Federal holiday ) View additional Frequently Asked Questions (FAQs) on the Small Business Transition Grant for New Entrepreneurs .
Note: Institutes and Centers (ICs) vary in their participation and the types of awards they support. See the NOFOs for full details, including complete eligibility and review criteria.
Activity Type Clinical Trials Funding Opportunity Number Participating ICs SBIR Not Allowed PAR-24-131 NCATS NIOSH (CDC) SBIR Required PAR-24-132 NCCIH NIOSH (CDC) STTR Not Allowed PAR-24-133 NCATS NLM STTR Required PAR-24-134 NCCIH National Institutes of Health Product Development Support Looking for the NIH SBIR & STTR site? The new seed. nih.
gov has everything you’re looking for about the NIH small business research and development programs (SBIR & STTR) . In addition, you can learn about other types of product development and commercialization support for NIH award recipients . Questions?
Check out About the NIH SEED Office or email us at [email protected] .
Based on current listing details, eligibility includes: Small businesses new to NIH SBIR/STTR funding, organized for profit, U. S. owned. Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates Varies by NOFO Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
The current target date is rolling deadlines or periodic funding windows. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.
Federal grant success rates typically range from 10-30%, varying by agency and program. Build a strong proposal with clear objectives, measurable outcomes, and a well-justified budget to improve your chances.
Requirements vary by sponsor, but typically include a project narrative, budget justification, organizational capability statement, and key personnel CVs. Check the official notice for the complete list of required attachments.
Yes — AI tools like Granted can help research funders, draft proposal sections, and check compliance. However, always review and customize AI-generated content to reflect your organization's unique strengths and the specific requirements of the solicitation.
Review timelines vary by funder. Federal agencies typically take 3-6 months from submission to award notification. Foundation grants may be faster, often 1-3 months. Check the program's timeline in the official solicitation for specific dates.
Many federal programs offer multi-year funding or allow competitive renewals. Check the official solicitation for continuation and renewal policies. Non-competing continuation applications are common for multi-year awards.
Purpose. This Funding Opportunity Announcement (FOA) solicits Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to develop, enhance and validate translational tools to facilitate rigorous study of complementary and alternative medicine (CAM) approaches that are in wide use by the public. Recent data from the National Health Interview Survey [http://www.cdc.gov/nchs/nhis.htm] establish that Americans are utilizing CAM approaches to promote health and well-being, to treat or prevent disease, and for symptom relief. CAM approaches being widely used include massage and manipulative therapies, meditation, yoga, and acupuncture. Health conditions, particularly chronic pain, back pain and musculoskeletal pain, are the most commonly cited reasons for their use. This FOA focuses on encouraging the development of improved tools to study safety, efficacy, and clinical effectiveness of widely used CAM approaches, such as: mind-body interventions, manual therapies, yoga, and acupuncture. This FOA is not focused on tools for the study of natural products, such as herbal therapies. Mechanism of Support. This FOA will utilize the SBIR (R43/R44) grant mechanisms for Phase I, Phase II, and Fast-Track applications and runs in parallel with a FOA of identical scientific scope, RFA-AT-09-002, which solicits applications under the R01 grant mechanism. Funds Available and Anticipated Number of Awards. The estimated amount of funds available for support of 5 projects awarded as a result of this announcement is $1.25 million for fiscal year 2010. Future year amounts will depend on annual appropriations. Funding Opportunity Number: RFA-AT-09-004. Assistance Listing: 93.213. Funding Instrument: G. Category: HL. Award Amount: $1.3M total program funding.
-Purpose. This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to develop, standardize, and validate new and innovative assays, integrated strategies, or batteries of assays that determine or predict specific organ toxicities (e.g., ocular, dermal, hematotoxicity, cardiotoxicity, gastrointestinal toxicity, hepatotoxicity, nephrotoxicity, ototoxicity, olfactory loss, bladder toxicity, neurotoxicity, pulmonary toxicity, endocrine toxicity, and pancreatic beta cell toxicity), resulting from both acute and chronic exposures to various chemicals, environmental pollutants, biologics and therapeutic molecules or drugs. In addition, this FOA encourages the development, standardization, and validation of new models of arthritis, convulsion, infection and shock. New approaches for high throughput toxicity screening that involves the use of molecular endpoints, computer modeling, proteomics, genomics and epigenomics and the development of virtual tissues are also encouraged as are development of 3-dimensional organ models for toxicity evaluation. -Mechanism of Support. This FOA will utilize the SBIR (R43/R44) grant mechanisms for Phase I, Phase II, and Fast-Track applications and runs in parallel with a FOA of identical scientific scope, PA-09-007, which encourages applications under the Small Business Technology Transfer (STTR) (R41/R42) grant mechanisms. Funding Opportunity Number: PA-09-006. Assistance Listing: 93.113,93.173,93.361,93.389,93.837,93.846,93.847,93.848,93.849,93.859,93.867. Funding Instrument: G. Category: ED,ENV,FN,HL.
-This Funding Opportunity Announcement (FOA) solicits Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) for the modification or development of new screening technologies that are better able to consistently detect mild hearing loss (i.e., less than 40 dB Hearing Level or 40 dB HL) in one or both ears in infants and young children without significantly increasing the number of false positives (i.e., those who fail the screen but do not have hearing loss). -The Early Hearing Detection and Intervention (EHDI) program within the National Center for Birth Defects and Developmental Disabilities (NCBDDD) of the Centers for Disease Control and Prevention (CDC) and the National Institute on Deafness and Other Communication Disorders (NIDCD), NIH, are working to ensure infants and children with mild forms of hearing loss are identified as soon as possible. Part of this effort involves having screening technology available that can reliably detect these hearing losses. -This FOA will utilize the SBIR (R43/R44) grant mechanisms for Phase I, Phase II, and Fast-Track applications and runs in parallel with a FOA of identical scientific scope, PA-06-547, that solicits applications under the Small Business Technology Transfer (STTR [R41/R42]) grant mechanisms. Note,that CDC does not accept STTR applications so is participating only in PA-06-546. Funding Opportunity Number: PA-06-546. Assistance Listing: 93.173,93.283. Funding Instrument: G. Category: HL.