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Small Molecule Approaches for Rapid and Robust Treatment (SMART) Antiviral Prize is sponsored by Biomedical Advanced Research and Development Authority (BARDA), HHS. This is a multi-stage prize competition to accelerate the development of broad-spectrum novel antiviral therapies targeting the Togaviridae and/or Flaviviridae virus families (e.g., dengue, Zika, West Nile, chikungunya).
The prize aims to strengthen the antiviral development pipeline by supporting innovative small-molecule approaches that can advance efficiently from early concept through Investigational New Drug (IND) readiness. The Concept Stage requires submission of a concept paper describing a plan to discover or advance a broad-spectrum antiviral candidate.
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Search similar grants →Based on current listing details, eligibility includes: Innovators working at the intersection of medicinal chemistry, virology, and translational drug development. Companies developing novel small-molecule antivirals. Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates Up to $100 million in total prize funding across multiple stages, with up to eight prizes of $2.5 million each for the Concept Stage. Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
The current target date is May 11, 2026. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.
Federal grant success rates typically range from 10-30%, varying by agency and program. Build a strong proposal with clear objectives, measurable outcomes, and a well-justified budget to improve your chances.
Requirements vary by sponsor, but typically include a project narrative, budget justification, organizational capability statement, and key personnel CVs. Check the official notice for the complete list of required attachments.
Yes — AI tools like Granted can help research funders, draft proposal sections, and check compliance. However, always review and customize AI-generated content to reflect your organization's unique strengths and the specific requirements of the solicitation.
Review timelines vary by funder. Federal agencies typically take 3-6 months from submission to award notification. Foundation grants may be faster, often 1-3 months. Check the program's timeline in the official solicitation for specific dates.
Many federal programs offer multi-year funding or allow competitive renewals. Check the official solicitation for continuation and renewal policies. Non-competing continuation applications are common for multi-year awards.
Past winners and funding trends for this program