TSET Legacy Grants is sponsored by Tobacco Settlement Endowment Trust (TSET). A historic funding opportunity aimed at addressing Oklahoma’s leading causes of death by supporting large-scale, multiyear projects in rural and underserved communities.

The Investment Has Been Made. Now the Work Begins. In 2025, TSET made a historic, <b>one-time $150 million investment</b> in Oklahoma's health through the TSET Legacy Grants.

Funding large-scale, transformational projects designed to tackle <b>cancer and cardiovascular disease</b>, the grants made an impact. </p>\r\n<p>More than <b>150 applications were received</b> from organizations across Oklahoma. Grants were awarded to projects that go beyond incremental change with scalable, evidence-based solutions built to last.

</p>\r\n"}}" id="text-3f95874ae3" class="cmp-text"> In 2025, TSET made a historic, one-time $150 million investment in Oklahoma's health through the TSET Legacy Grants. Funding large-scale, transformational projects designed to tackle cancer and cardiovascular disease , the grants made an impact. More than 150 applications were received from organizations across Oklahoma.

Grants were awarded to projects that go beyond incremental change with scalable, evidence-based solutions built to last. Board of Regents of the University of Oklahoma Health and Sciences <i>Improved Access to Clinical Trials</i></p>\n"}}" id="text-0cba4da120" class="cmp-text"> Improved Access to Clinical Trials <b>$25,000,000<br>\n</b><span style=\"font-size: 1. 125rem; letter-spacing: 0.

43px;\">Goal to increase access to clinical trials in Tulsa and Northeast Oklahoma through the new TSET Clinical Research Center. </span></p>\n"}}" id="text-218bedd3de" class="cmp-text"> Goal to increase access to clinical trials in Tulsa and Northeast Oklahoma through the new TSET Clinical Research Center.

Oklahoma State University Medical Center <i>Advancing Healthcare Education and Workforce Development Across Oklahoma</i></p>\n"}}" id="text-fd9b651ae6" class="cmp-text"> Advancing Healthcare Education and Workforce Development Across Oklahoma <b>$30,000,000<br>\n</b><span style=\"font-size: 1. 125rem; letter-spacing: 0.

43px;\">Goal to develop a state-of-the-art facility for graduate medical education and allied health workforce training. This will allow for 100 additional physician residency positions across eastern/northeastern Oklahoma. </span></p>\n"}}" id="text-23406337ff" class="cmp-text"> Goal to develop a state-of-the-art facility for graduate medical education and allied health workforce training.

This will allow for 100 additional physician residency positions across eastern/northeastern Oklahoma. Dan Hays STEM Center/School of Nursing</p>\n"}}" id="text-ca7af3037b" class="cmp-text"> Dan Hays STEM Center/School of Nursing <b>$13,147,000<br>\n</b><span style=\"font-size: 1. 125rem; letter-spacing: 0.

43px;\">Goal to address nursing shortage in Oklahoma by increasing nursing program capacity and enhancing all healthcare students’ training in the new Dan Hays STEM center. </span></p>\n"}}" id="text-0f6bd640b8" class="cmp-text"> Goal to address nursing shortage in Oklahoma by increasing nursing program capacity and enhancing all healthcare students’ training in the new Dan Hays STEM center.

Oklahoma Medical Research Foundation Oklahoma Medical Research Foundation’s <i>TSET Institute for a Healthier Oklahoma </i><span style=\"font-size: 1. 125rem; letter-spacing: 0. 43px;\">will expand research and telehealth opportunities addressing three root causes underlying chronic disease: inflammation, impaired immunity and accelerated aging ($9,878,000).

</span></p>\n"}}" id="text-517e554954" class="cmp-text"> Oklahoma Medical Research Foundation’s TSET Institute for a Healthier Oklahoma will expand research and telehealth opportunities addressing three root causes underlying chronic disease: inflammation, impaired immunity and accelerated aging ($9,878,000).

Community Health Connection Community Health Connection’s <i>Maternal and Child Health Clinic</i> will expand low-cost pediatric, obstetrics and gynecology services in Tulsa County with a new clinic and three direct care teams ($4,400,000).

</p>\n"}}" id="text-d97edc84cf" class="cmp-text"> Community Health Connection’s Maternal and Child Health Clinic will expand low-cost pediatric, obstetrics and gynecology services in Tulsa County with a new clinic and three direct care teams ($4,400,000).

Healthy Minds Policy Initiative, LLC Healthy Minds Policy Initiative, LLC’s <i>Oklahoma Integrated Care Resource Center</i> will improve chronic disease outcomes by creating a statewide resource for integrating <span style=\"font-size: 1. 125rem; letter-spacing: 0. 43px;\">behavioral health in primary care settings ($5,570,000).

</span></p>\n"}}" id="text-c6ba677ac7" class="cmp-text"> Healthy Minds Policy Initiative, LLC’s Oklahoma Integrated Care Resource Center will improve chronic disease outcomes by creating a statewide resource for integrating behavioral health in primary care settings ($5,570,000). Oklahoma Hospital Association The Oklahoma Hospital Association’s <i>Healthy Oklahoma Communities Initiative </i>will <span style=\"font-size: 1.

125rem; letter-spacing: 0. 43px;\">improve patient outcomes by integrating lifesaving telestroke care in rural hospitals, and piloting Community Health Workers (CHW) in several regions of the state. CHW services will include screening, patient navigation and community engagement ($3,220,000).

</span></p>\n<p>The Oklahoma Hospital Association’s <i>HOPE Initiative: Helping Oklahomans with </i><i style=\"font-size: 1. 125rem; letter-spacing: 0. 43px;\">Prevention and Early Detection Lung Cancer Screening & Tobacco Cessation Saves Lives </i><span style=\"font-size: 1.

125rem; letter-spacing: 0. 43px;\">will increase preventative lung cancer screening and tobacco cessation services through public awareness campaigns, patient navigation and health systems coordination ($18,690,000).

</span></p>\n"}}" id="text-6919db9d28" class="cmp-text"> The Oklahoma Hospital Association’s Healthy Oklahoma Communities Initiative will improve patient outcomes by integrating lifesaving telestroke care in rural hospitals, and piloting Community Health Workers (CHW) in several regions of the state. CHW services will include screening, patient navigation and community engagement ($3,220,000).

The Oklahoma Hospital Association’s HOPE Initiative: Helping Oklahomans with Prevention and Early Detection Lung Cancer Screening & Tobacco Cessation Saves Lives will increase preventative lung cancer screening and tobacco cessation services through public awareness campaigns, patient navigation and health systems coordination ($18,690,000).

The Chickasaw Foundation’s <i>Once-in-a-Century Opportunity to Transform the Health </i><i style=\"font-size: 1. 125rem; letter-spacing: 0. 43px;\">Outcomes of First Americans in Oklahoma through Graduate Medical Education</i> will <span style=\"font-size: 1.

125rem; letter-spacing: 0. 43px;\">establish two residency programs (pediatrics and obstetrics/gynecology) and three fellowship programs (pediatric endocrinology, endocrinology and rheumatology) for the Chickasaw Nation Department of Health complex in Newcastle ($6,778,000).

</span></p>\n"}}" id="text-ab086b18df" class="cmp-text"> The Chickasaw Foundation’s Once-in-a-Century Opportunity to Transform the Health Outcomes of First Americans in Oklahoma through Graduate Medical Education will establish two residency programs (pediatrics and obstetrics/gynecology) and three fellowship programs (pediatric endocrinology, endocrinology and rheumatology) for the Chickasaw Nation Department of Health complex in Newcastle ($6,778,000).

Durant Family Medicine Clinic Durant Family Medicine Clinic’s <i>Durant Health Access & Innovation Initiative</i> will <span style=\"font-size: 1. 125rem; letter-spacing: 0. 43px;\">improve access, prevent chronic disease and strengthen rural health care workforce through telehealth expansion, prevention-focused care, provider education and regional outreach ($3,000,000).

</span></p>\n"}}" id="text-38f8e2d01a" class="cmp-text"> Durant Family Medicine Clinic’s Durant Health Access & Innovation Initiative will improve access, prevent chronic disease and strengthen rural health care workforce through telehealth expansion, prevention-focused care, provider education and regional outreach ($3,000,000).

Rogers State University Foundation Rogers State University Foundation will create a <i>Bachelor of Science in Nutrition Science Program </i>to help meet a regional workforce demand for dietitians and nutrition professionals due to high rates of obesity, diabetes and health issues caused by poor nutrition ($3,017,000).

</p>\n"}}" id="text-03000bf2dc" class="cmp-text"> Rogers State University Foundation will create a Bachelor of Science in Nutrition Science Program to help meet a regional workforce demand for dietitians and nutrition professionals due to high rates of obesity, diabetes and health issues caused by poor nutrition ($3,017,000).

The Youth Medical Mentorship’s <i>Home-Grown Health Professional Pipeline</i> will address provider shortages by identifying and mentoring Oklahoma youth interested in medical careers ($500,000). </p>\n"}}" id="text-195a081c55" class="cmp-text"> The Youth Medical Mentorship’s Home-Grown Health Professional Pipeline will address provider shortages by identifying and mentoring Oklahoma youth interested in medical careers ($500,000).

Food Bank of Eastern Oklahoma The Food Bank of Eastern Oklahoma’s FEEDOK – will provide nutritious, convenient, pre-made meals to food-insecure, low-income students to take home when school meals are unavailable after school, during weekends and on school breaks. The program aims to serve students in 200 school districts in all 77 Oklahoma counties ($9,429,000).

</p>\n"}}" id="text-4a276bf309" class="cmp-text"> The Food Bank of Eastern Oklahoma’s FEEDOK – will provide nutritious, convenient, pre-made meals to food-insecure, low-income students to take home when school meals are unavailable after school, during weekends and on school breaks. The program aims to serve students in 200 school districts in all 77 Oklahoma counties ($9,429,000).

The City of Tulsa’s <i>North Tulsa Wellness Initiative: A Community Collaboration to Address Prevention, Wellness and Quality of Life</i> will improve the health and quality of <span style=\"font-size: 1. 125rem; letter-spacing: 0. 43px;\">life for Hawthorne and Whitman neighborhood residents.

This historic cooperative effort will create a replicable model to transform the health and well-being of a chronically underserved community by increasing access to primary care, tobacco cessation, fresh produce and physical activity opportunities amid a multitude of community resources ($17,360,000).

</span></p>\n"}}" id="text-72cb270fd4" class="cmp-text"> The City of Tulsa’s North Tulsa Wellness Initiative: A Community Collaboration to Address Prevention, Wellness and Quality of Life will improve the health and quality of life for Hawthorne and Whitman neighborhood residents.

This historic cooperative effort will create a replicable model to transform the health and well-being of a chronically underserved community by increasing access to primary care, tobacco cessation, fresh produce and physical activity opportunities amid a multitude of community resources ($17,360,000). TSET Legacy Grants required a minimum of $3 million per project, with durations ranging from one to three years.

Funded projects targeted major health impacts for Oklahomans in rural health, health care access, data gaps, early prevention and quality of life. Awarded projects focus on scalable, launch-ready work built to sustain itself beyond the grant term.

</p>\r\n<p>Grants were awarded to public universities, state agencies, nonprofits, public entities and tribal organizations that demonstrated broad reach, evidence-based practices and the capacity to manage reimbursable funds. </p>\r\n<p><b>Ready to make a healthy change in your community? Explore all of TSET’s grant opportunities.

</b></p>\r\n"}}" id="text-43c6b22391" class="cmp-text"> TSET Legacy Grants required a minimum of $3 million per project, with durations ranging from one to three years. Funded projects targeted major health impacts for Oklahomans in rural health, health care access, data gaps, early prevention and quality of life. Awarded projects focus on scalable, launch-ready work built to sustain itself beyond the grant term.

Grants were awarded to public universities, state agencies, nonprofits, public entities and tribal organizations that demonstrated broad reach, evidence-based practices and the capacity to manage reimbursable funds. Ready to make a healthy change in your community? Explore all of TSET’s grant opportunities.

Tobacco Settlement Endowment Trust 2800 N. Lincoln Blvd. , Suite 202 Oklahoma Tobacco Helpline