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Food irradiation is a food preservation method which is used in many countries, both in human and animal food manufacturing. Treating food with irradiation results in large reduction in microbial contamination and insect pests. It is also useful in slowing ripening of fruit and for inhibiting sprouting of plant products. In USA, the FDA regulates all aspects of irradiation, such as irradiation dose, product type, and labeling requirements. The use of irradiation requires development of analytical methods capable to determine the irradiation status of wide variety of foods, in order to ensure that food is properly labeled, as well as to insure that products were properly handled during irradiation process. Current FDA regulations allow a maximum absorbed dose of 50 kGy in animal feed, pet food, and treats that are irradiated to reduce microbial and insect pest contamination. There are however, very few tests, with limited application, to quantify the actual dose used when irradiating animal food products. Depending on the type of food, various methods are available to detect food irradiation. For fatty foods, the major methods are based on chemical determination of compounds formed from the irradiation of lipids (hydrocarbons and 2-alkylcyclobutanones). It is believed that 2-alkylcyclobutanones (2-ACBs) are formed in food only by irradiation, and they are considered as markers for detecting the irradiation in food. Electron spin resonance (ESP) spectroscopy detects irradiation induced paramagnetic centers (e.g. radicals). This method is applicable for detection of irradiated foods containing bone, cellulose or crystalline sugar. Thermoluminescence is a method applicable to those foods from which a sufficient amount of silicate minerals can be isolated. Photostimulated luminescence is a different method, which can be applied to detect irradiation of any food which contains mineral debris. DNA comet assay can be used to detect irradiation of any food containing DNA, with several limitations. Different microbiological methods are also available, but can only be used as a screening tool.The current funding opportunity is designed to develop analytical methods for detection and quantification of markers such as 2-ACB's in animal feeds and treats to help the FDA to determine and regulate the dose of irradiation that was used during production. Eligibility is limited to domestic (U.S) applicants.
Funding Opportunity Number: PAR-16-132. Assistance Listing: 93.103. Funding Instrument: CA. Category: AG,CP,FN. Award Amount: Up to $99K per award.
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Search similar grants →Based on current listing details, eligibility includes: Eligible applicants: State governments; County governments; City or township governments; Special district governments; Independent school districts; Public and State controlled institutions of higher education; Native American tribal governments (Federally recognized); Public housing authorities / Indian housing authorities; Native American tribal organizations (other than Federally recognized); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; For-profit organizations other than small businesses; Small businesses. Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates Up to $99K per award Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
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The Food and Drug Administration (FDA), Center for Drug Evaluation and Research (CDER), Office of Medical Policy (OMP) is announcing its intent to accept and consider a single source application for the award of a grant to the Duke Universitys Duke Translational Medicine Institute (DTMI) to support increasing the quality and efficiency of clinical trials. Funding Opportunity Number: RFA-FD-14-017. Assistance Listing: 93.103. Funding Instrument: G. Category: FN,HL. Award Amount: Up to $7.5M per award.
The Center for Drug Evaluation and Research (CDER) receives a vast and growing amount of data in a variety of regulatory submissions from a multitude of sources and in a variety of formats. This wealth of data holds great potential to advance CDER’s regulatory and scientific work, but the present lack of standardized data creates significant challenges to realizing that potential.The volume and complexity of drug-related information submitted to CDER for regulatory review is creating significant challenges to the Center’s ability to efficiently and effectively perform its critical public health mission.The lack of standardized data affects CDER’s review processes by curtailing a reviewer’s ability to perform integral tasks such as rapid acquisition, analysis, storage and reporting of regulatory data. Improved data quality, accessibility and predictability will give reviewers more time to carry out complex analyses, ask in-depth questions and address late-emerging issues. Standardized data will allow reviewers to increase review consistency and perform evaluations across the drug lifecycle. This will enhance the Center’s performance across key drug regulatory functions and ongoing business operations, including pre-market review, post-market safety, oversight of drug quality, and oversight of drug promotion.In accordance with the Office of Management and Budget (OMB) Circular A-119, the FDA will: use voluntary, consensus-based standards development processes in place of government unique standards unless such standards are inconsistent with law or otherwise impractical; advocate to align these standards with existing health information technology initiatives, laws, regulations, and mandates; and promote coordination with other standards currently in use. The projects selected under this funding opportunity must adhere to these principles. Funding Opportunity Number: RFA-FD-15-033. Assistance Listing: 93.103. Funding Instrument: CA. Category: FN,IS. Award Amount: $50K – $225K per award.
The Food and Drug Administration (FDA), Center for Food Safety and Applied Nutrition (CFSAN), Office of Food Safety (OFS) is announcing its intent to award a single source cooperative agreement to the Interstate Shellfish Sanitation Conference (ISSC). The purpose of this cooperative agreement is to enhance the FDA’s molluscan shellfish sanitation program and provide the public greater assurance of the quality and safety of these products. Molluscan shellfish have been recognized by FDA as a significant source of seafood-borne illnesses and continue to be the subject of congressional, state, industry, and public concern. FDA has given high priority to enhance the agency's shellfish safety program and to provide the public greater assurance of the quality and safety of these products. FDA administers the National Shellfish Sanitation Program (NSSP). Under that program, the NSSP Model Ordinance serves as guidance for State shellfish sanitation programs and the promulgation of state regulations and laws concerning shellfish safety. This cooperative agreement will enhance FDA efforts to help ensure that shellfish are free of harmful pathogens. Funding Opportunity Number: RFA-FD-16-006. Assistance Listing: 93.103. Funding Instrument: CA. Category: AG,CP,FN. Award Amount: Up to $500K per award.