CDC's $1.26B cancer prevention recompete, CDC-RFA-DP-27-0023, closes February 5, 2027. What tribal and community-based organizations should be doing now.
HHS forecast HHS-2027-ACF-OHS-CH-0112 puts $818.3M across 255 Head Start awards in 37 states. The NOFO posts Oct 14; applications close Dec 15, 2026.
SBA's new SBIR/STTR commercialization standard demands 33% then 50% non-SBIR revenue from firms with 25+ Phase II awards. Comments close October 31, 2026.
NIH forecast PAR-28-060 puts $5M and 16 awards behind shared-use lab instruments, and unlike S10 it never asks for three NIH-funded PIs. Deadline Sept 25.
NIMHD forecast RFA-MD-27-004: $3M across ~10 R34 planning grants for Native Hawaiian and Pacific Islander health. NOFO Dec 16, applications due Feb 16, 2027.
HRSA's Appalachian Region Healthcare Support Program (HRSA-27-053) forecasts $2.5M for one FY2027 award. The deadline that matters to your clinic closes Sept 4.
HRSA's FY2027 Rural Health Network Development forecast (HRSA-27-051) lists $9M across 23 awards and a March 16, 2027 deadline. The 3-org rule starts now.
IHS forecasts $5M for tribal behavioral health integration: HHS-2027-IHS-BH2I-0001, 15 awards, applications estimated due March 1, 2027. Prep now.
NIDDK forecast RFA-DK-28-116: one $5M U01 for multimodal AI in type 1 diabetes. Full NOFO est. Dec 1, 2026; applications estimated due February 10, 2027.
NSF 26-516 (GEO Core) puts $110M behind 200-350 geoscience awards with no deadline, no award floor, and no per-PI proposal limit. What PIs should do now.
NIFA's $5.7M Higher Education Challenge grants (USDA-NIFA-CGP-011315) close Oct 15, 2026 — but community colleges can't lead an application. Here's the way in.
ONDCP's RD-ET-RDA-26-001 offers $300,000 to one tribal organization to build drug-threat detection capacity. Posted August 14, closes August 31, 2026.
HRSA-27-042 forecasts $3 million and just six awards for RCORP Community Systems Development, due April 6, 2027. Why rural CBOs win it as consortium members.
NIH is retiring the K99/R00. PA-28-048 (KT1/R00) replaces it, every current K NOFO expires July 13, 2027, and the first new deadline is October 12, 2027.
SBA's SB-OEDCS-26-002 puts $5M into small-manufacturer cyber resilience in Indiana, Ohio and Virginia. Defense SBIR firms can't apply — here's the play.
IHS forecast HHS-2027-IHS-EPI-0001 puts $7M behind two Tribal Epidemiology Center awards for unserved IHS Areas. Estimated application deadline: April 1, 2027.
NSF 26-513 puts $100M behind ~10 State and Regional AI Infrastructure Hubs at $4M-$12M each. One award per state, proposals due November 4, 2026.
DOE's $100M PROSPECT notice of intent (DE-FOA-0003662) aims to double minerals graduates in two years, a target only short-credential programs can hit.
USDA's FY2026 Housing Preservation Grant posts $8.3M with a September 8 deadline. The general pool absorbed nearly the whole cut. What nonprofits should do.
NIH's RNomics Technology Enhancement Centers (RFA-RM-28-005) forecast $12M for 4 awards, due Feb 1, 2027. How the $151M program's four RFAs split.
HRSA-27-046 forecasts $11.25M and 15 awards of up to $750K for rural residency development. Synopsis Dec 18, applications due Mar 18, 2027. No match required.
ACF just posted a $29M diaper pilot with 14 awards and a Sept 15 deadline. The eligibility door is narrow and the evaluation is the real scoring surface.
One Federal Register notice opened five FY2027 IES competitions - 84.305B, 84.324B, 84.305D, 84.305S, 84.324S - with $1.2M ceilings and an October 1 deadline.
NSF awarded $108M to six new MRSEC materials centers under NSF 26-500 — $18M each over six years. What the award size signals for PIs planning the next cycle.
ACF is awarding $143,436,162 in Head Start disaster grants with no competition. The 46 recipients were set before the storms. What EDs should learn from it.
ANA posted HHS-2026-ACF-ANA-NAI-0035: a single $3.5M cooperative agreement to build an AI institute for Indian Country. Tribal applicants have until August 27.
NIH forecast PAR-28-037, the Investigator-Focused Award (Parent R35), July 30, 2026. Nine ICs, an Oct 4, 2027 estimated deadline, no published budget cap.
CDC forecast CDC-RFA-PS-27-0239 puts $82.5M behind harm-reduction infectious disease services. Why rural and tribal CBOs should target subawards, not prime.
HRSA-27-044 forecasts $4.5M and 15 awards for telehealth nutrition networks, with the full NOFO expected Feb 2, 2027. What nonprofit EDs should build now.
CDC forecast RFA-DP-27-036: $7.25M and two awards to pilot and evaluate cervical, breast and colorectal cancer CDS tools. Applications est. March 23, 2027.
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