Medical Scientist Training Program (MSTP) (T32) is sponsored by National Institutes of Health (NIH). Provides institutional support for dual-degree training programs in medicine and biomedical research, aiming to develop physician-scientists.

PAR-24-128: Medical Scientist Training Program (MSTP) (T32) This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission. Department of Health and Human Services Part 1.

Overview Information Participating Organization(s) National Institutes of Health ( NIH ) Components of Participating Organizations National Institute of General Medical Sciences ( NIGMS ) Funding Opportunity Title Medical Scientist Training Program (MSTP) (T32) T32 Institutional National Research Service Award (NRSA) July 16, 2025 - Notice of Change to Enhance the Organizational Participation in the Medical Scientist Training Program.

See Notice NOT-GM-25-024 . March 31, 2025 - This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.

January 02, 2025 - Notice of Change to Date for Virtual Question & Answer Office Hour for NIGMS Predoctoral Basic Biomedical and Dual-Degree Clinician Scientist Training Programs. See Notice NOT-GM-25-018 . April 04, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025.

See Notice NOT-OD-24-084 December 17, 2024 - Notice of Virtual Question & Answer Office Hour for NIGMS Predoctoral Basic Biomedical and Dual-Degree Clinician Scientist Training Programs. See Notice NOT-GM-25-015 . October 1, 2024 - Updates to NIGMS Predoctoral Basic Biomedical Sciences Research Training Program and Medical Scientist Training Program (MSTP) T32 Training Grant Applications for Due Dates on and after January 25, 2025.

See Notice NOT-GM-24-053 . March 21, 2024 - Notice of Informational Webinar for the National Institute of General Medical Sciences Medical Scientist Training Program (MSTP) (T32).

See Notice NOT-GM-24-029 October 26, 2022 - Reminder: FORMS-H Grant Application Forms & Instructions Must be Used for Due Dates On or After January 25, 2023 - New Grant Application Instructions Now Available see Notice NOT-OD-23-012 August 8, 2022 - New NIH "FORMS-H" Grant Application Forms and Instructions Coming for Due Dates on or after January 25, 2023 see Notice NOT-OD-22-195 Funding Opportunity Number (FON) Companion Funding Opportunity Institutional National Research Service Award See Section III.

3. Additional Information on Eligibility. Assistance Listing Number(s) Funding Opportunity Purpose The goal of the Medical Scientist Training Program (MSTP) is to develop a pool of well-trained clinician-scientist leaders available to address the nation’s biomedical research needs.

Specifically, this funding announcement provides support to eligible, domestic organizations to develop and implement effective, evidence-informed approaches to dual-degree training and mentoring that will keep pace with the rapid evolution of the biomedical research enterprise and lead to the completion of both a clinical degree (for example, M. D. , D.

O. , D. V.

M. , D. D.

S. , Pharm. D.

, etc.) and a research doctorate degree (Ph. D.) With the dual qualifications of a rigorous scientist and clinician, graduates will be equipped with the skills to develop research programs that accelerate the translation of research advances to the understanding, detection, treatment, and prevention of human disease, and to lead the advancement of biomedical research.

Areas of particular importance to NIGMS are optimizing training efficiency, fostering the persistence of alumni in research careers, and enhancing the clinician-scientist workforce. NIGMS expects that the proposed research training program will incorporate didactic, research, mentoring and career development elements to prepare trainees for careers that will have a significant impact on the health-related research needs of the nation.

This Notice of Funding Opportunity (NOFO) does not allow appointed Trainees to lead an independent clinical trial, but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor. Open Date (Earliest Submission Date) Letter of Intent Due Date(s) The following table includes NIH standard due dates marked with an asterisk.

Renewal / Resubmission / Revision (as allowed) AIDS - New/Renewal/Resubmission/Revision, as allowed All applications are due by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Required Application Instructions It is critical that applicants follow the Training (T) Instructions in the SF424 (R&R) Application Guide , except where instructed to do otherwise (in this NOFO or in a Notice from the NIH Guide for Grants and Contracts ). Conformance to all requirements (both in the Application Guide and the NOFO) is required and strictly enforced.

Applicants must read and follow all application instructions in the Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions. Applications that do not comply with these instructions may be delayed or not accepted for review.

There are several options available to submit your application through Grants. gov to NIH and Department of Health and Human Services partners. You must use one of these submission options to access the application forms for this opportunity.

Use the NIH ASSIST system to prepare, submit and track your application online. Use an institutional system-to-system (S2S) solution to prepare and submit your application to Grants. gov and eRA Commons to track your application.

Check with your institutional officials regarding availability. Workspace to prepare and submit your application and eRA Commons to track your application. Part 1.

Overview Information Part 2. Full Text of Announcement Section I. Funding Opportunity Description Section II.

Award Information Other Award Budget Information Section III. Eligibility Information Section IV. Application and Submission Information Section V.

Application Review Information Section VI. Award Administration Information Section VII. Agency Contacts Section VIII.

Other Information Part 2. Full Text of Announcement Section I. Funding Opportunity Description Purpose and Background Information The overall goal of the NIH Ruth L.

Kirschstein National Research Service Award (NRSA) program is to help ensure that a pool of highly trained scientists is available in appropriate scientific disciplines to address the nation's biomedical, behavioral, and clinical research needs. More information about NRSA programs may be found at the Ruth L. Kirschstein National Research Service Award website.

The NRSA program has been the primary means of supporting predoctoral and postdoctoral research training programs since enactment of the NRSA legislation in 1974.

Each NIGMS-funded MSTP award is expected to provide a rigorous, well-designed research training program that includes mentored research experiences, courses, seminars, and additional training opportunities that equip clinician scientists with the following skills required for careers in the biomedical research workforce: Technical (for example, appropriate methods, technologies, and quantitative/computational approaches).

Operational (for example, independent knowledge acquisition, rigorous experimental design, interpretation of data, and conducting research in the safest manner possible). Professional (for example, management, leadership, communication, and teamwork).

Through this funding announcement, NIGMS encourages changes in integrated clinical and graduate research training to keep pace with the rapid evolution of the biomedical research enterprise, which is increasingly complex, interdisciplinary, quantitative, and collaborative.

Other changes in the biomedical research enterprise include the approaches utilized to investigate clinically relevant research questions, and the range of careers that dual-degree recipients are pursuing.

Additionally, there is an increasing recognition of the need to enhance reproducibility of biomedical research results through scientific rigor and transparency , and to promote a culture where the highest standards of practice are used to ensure the safety of all individuals in the research environment.

This funding opportunity is intended to encourage and enable the scientific community to develop and implement evidence-informed approaches to biomedical research training and mentoring that will effectively train future, rigorous clinician scientists to become leaders in biomedical research and clinical medicine.

Programs are encouraged not to simply layer additional activities onto existing structures but to instead use creative and transformational approaches to integrate clinical and biomedical graduate training, including curricular reform, that preserve the best elements of current programs, while enhancing the focus on the development of trainee skills.

NIGMS strives to ensure that future researchers will be drawn from the entire pool of potential contributors and seeks to support individuals at multiple training and career stages in a variety of organizations and educational settings across the country. The Overarching Objective of the MSTP is to develop a pool of well-trained clinician scientists (that is, a Ph. D.

combined with a clinical degree, such as an M. D. , D.

O. , D. V.

M. , D. D.

S. , Pharm. D.

, etc.) who have the following: A broad understanding across biomedical disciplines. The skills to independently acquire the knowledge needed to advance their chosen fields and careers. The ability to think critically and identify important biomedical research questions and approaches that push forward the boundaries of their areas of study.

A strong foundation in scientific reasoning, rigorous research design, experimental methods, quantitative and computational approaches, and data analysis and interpretation. The skills to conduct research in the safest manner possible, and a commitment to approaching and conducting biomedical research responsibly, ethically, and with integrity.

Experience initiating, conducting, interpreting, and presenting rigorous and reproducible biomedical research with increasing self-direction. The ability to utilize clinical experience and observations to identify biomedical research questions and to develop impactful research programs that push forward the boundaries of their areas of study.

The skills necessary to integrate research and clinical activities and the capacity to translate scientific research findings into clinical practice. The ability and skills to lead changes that promote health for all, reduce health disparities and improve the health of those medically underserved across diseases, disorders, and conditions.

The ability to work effectively in teams with colleagues from a variety of scientific backgrounds, and to promote safe and supportive scientific research environments. The skills to teach and communicate scientific methodologies and findings to a wide variety of audiences (for example, discipline-specific, across disciplines, and for the public).

The knowledge, professional skills and experiences required to identify and transition into careers in the biomedical research workforce that utilize the dual-degrees (for example, the breadth of careers that sustain biomedical research in areas that are relevant to the NIH mission).

NIGMS will accept predoctoral training grant applications supporting integrated clinician and graduate research training through this MSTP funding announcement and subsequent reissuances (graduate research training in basic biomedical sciences is supported through PAR-23-228 and subsequent reissuances).

Applicants are strongly encouraged to read information about NIGMS predoctoral training grant programs, found on the NIGMS website and to contact program staff before preparing or submitting an application to verify that the proposed program is eligible and in alignment with NIGMS funding priorities. General Considerations.

NIGMS intends to fund applications that propose feasible, rigorous, well-designed and integrated dual-degree research training programs that will build on the most effective elements of successful programs, while encouraging creative and transformational approaches to clinician scientist research training, ranging from curricular reform to changes in the research training environment.

Funded programs should implement plans to optimize the time required to earn the dual degree. Programs are expected to limit appointments to individuals committed to research careers that utilize the dual-degree qualifications.

NIGMS encourages programs to devise and test alternative entry pathways in addition to or instead of the direct application and admission to the first year of the dual-degree training program, thus providing opportunities to recruit students from clinician-only or from Ph. D. -only programs.

NIGMS encourages institutions to offer MSTP trainees the opportunity to earn the Ph. D. in a broad range of biomedical, physical, and social and behavioral sciences, and engineering to meet the needs for clinician scientist researchers in all areas of the biomedical workforce.

Programs that provide interdisciplinary research training, incorporate training in data science, or take advantage of clinical research opportunities within nationwide networks and infrastructures such as the NIH Clinical and Translational Science Award program are encouraged to apply.

NIGMS encourages applicants to offer training across the landscape of medical fields and scientific disciplines related to health, and to promote opportunities for the exploration of clinician scientist career options. Funded programs are expected to: Be a well integrated dual-degree program that exerts a strong, positive influence at the organizational level on research training and mentoring practices.

Have clearly defined training objectives and show evidence of meeting the objectives in progress reports and in renewal applications. Implement evidence-informed training and mentoring activities (for example, approaches that are grounded in the literature and evaluations of existing relevant dual-degree research training programs). Programs are expected to be responsive to evaluations, particularly with respect to trainee feedback.

Provide rigorous, well-designed mentored research experiences, and additional opportunities that will build a strong cohort of dual-degree research-oriented individuals. Training grant funds may not be used solely as a vehicle to provide financial aid for trainees to conduct research.

Demonstrate effective oversight of dual-degree trainee development and promote retention for the entire time the dual-degree trainee is in the training program. Retention efforts are activities designed to sustain the scientific interests and participation of all trainees.

Retention and oversight activities might include monitoring academic and research progress, building strong trainee cohorts, as well as increasing science identity, self-efficacy, and a sense of belonging within research training environments. Programs are expected to make efforts to identify individuals who may need additional academic and social supports to successfully complete the program, and ensure they receive the needed support.

Promote safe and supportive research training environments to maximize success for all individuals in the training program. Specifically, funded programs should have organizational and departmental environments where all individuals are welcomed, feel integrated into, and supported by the biomedical research community.

Safety in research training should encompass (1) environments free from harassment, discrimination, and intimidation, in which all are treated in a respectful and supportive manner, (2) laboratory and clinical settings where individuals exercise the highest standards of practice for chemical, biological and physical safety, and (3) practices at the organizational leadership and research community levels that demonstrate core values and behaviors to emphasize safety over competing goals.

Trainee Support. The training grant defrays the cost of stipends, tuition and fees, and training related expenses, including health insurance, for the appointed trainees in accordance with the approved NIH NRSA support levels. NIGMS typically provides full-time support for approximately 25% of the trainees in the training program during any given year.

Individuals may receive up to six years of aggregate Kirschstein-NRSA support at the predoctoral level for dual-degree training, including any combination of support from institutional training grants (for example, T32) and an individual fellowship award (for example, F30 or F31 awards).

Many dual-degree training programs guarantee enrolled students full support for the duration of the dual-degree program (through combinations of federal support, institutional funds, other fellowships, and grants). Training programs may implement institutional policies regarding payback of non-NRSA institutional sources of funds by students who start training but do not complete one or both degrees.

NIGMS does not require nor permit institutions to receive payback NRSA funds from trainees who are appointed to NIH training grants, but do not complete training. Synergies of Federally Funded Training Programs.

Funded research training programs are encouraged to complement and synergize with other ongoing federally supported predoctoral research training programs at the applicant organization (for example, in the development of skills needed for careers in the biomedical research workforce that are not discipline-specific); however, the scientific training goals must be distinct from related programs at the same organization currently receiving federal support.

In cases where an organization has multiple NIGMS predoctoral training grants, it is expected that these programs will work together to create administrative and training efficiencies to reduce costs and improve trainee services and outcomes. Type of Application Submissions.

Please note the following before applying: Applications will be considered a RENEWAL application only if the program described in the application was funded previously through NIGMS funding opportunity announcements PAR-19-036 or PAR-21-189 . RESUBMISSION applications are only accepted for RENEWAL applications.

Renewal applications that are not funded on the initial attempt may be revised and resubmitted as a Resubmission application (for example, -A1) New applications that are not funded are not allowed to submit a Resubmission application.

Instead, new applications that are not successful are encouraged to apply again by submitting another new application that utilized constructive feedback from the previous review, while following the instructions for New Applications (for example, do not refer to the prior application or critiques). Administered an NIGMS MSTP that was funded through a parent grant announcement (for example, PA-16-152 , PA-18-403 ).

NIGMS will not accept applications for MSTP with any of the following: Submitted through the NIGMS Predoctoral Basic Biomedical Sciences T32 or any subsequent reissuance. Submitted through the Parent T32 funding opportunity announcement, PA-23-048 or any subsequent reissuances. Propose short-term research training.

Include combined predoctoral and postdoctoral training programs. For applicants that currently have an NIGMS institutional predoctoral MSTP, NIGMS recommends that applicants plan to apply under this funding announcement at least one- to one-and-a half years before the current grant is scheduled to terminate.

For example, if the current grant is scheduled to terminate on July 30, 2025, applicants are advised to submit an application to this funding announcement no later than May 25, 2024. Please consult the NIGMS website for more information on Predoctoral Training Grant Application Deadlines. Clinical Trials.

This notice of funding opportunity does not allow appointed trainees to lead an independent clinical trial but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor. NIH strongly supports training towards a career in clinically relevant research; gaining experience in clinical trials under the guidance of a mentor or co-mentor is encouraged. See Section VIII.

Other Information for award authorities and regulations. Section II. Award Information Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.

Application Types Allowed Renewal - Renewal of awards submitted to PAR-19-036 or PAR-21-189 Resubmission - Resubmissions are only allowed for Renewal Applications The OER Glossary and the SF424 (R&R) Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO. Not Allowed: Only accepting applications that do not propose clinical trials.

Note: Appointed Trainees are permitted to obtain research experience in a clinical trial led by a mentor or co-mentor. Need help determining whether you are doing a clinical trial? Funds Available and Anticipated Number of Awards The number of awards is contingent upon NIH appropriations and the number of meritorious applications submitted.

Application budgets are not limited but must reflect the actual needs of the proposed project. Recipients are expected to be familiar with and comply with applicable cost policies and the NRSA Guidelines ( NIH Grants Policy Statement - Institutional Research Training Grants ).

Funds may be used only for those expenses that are directly related to and necessary for the research training and must be expended in conformance with OMB Cost Principles, the NIH Grants Policy Statement , and the NRSA regulations, policies, guidelines, and conditions set forth in this document. Awards may be for project periods up to five years in duration and are renewable.

Other Award Budget Information Stipends, Tuition, and Fees Kirschstein-NRSA awards provide stipends as a subsistence allowance to help defray living expenses during the research training experience. NIH will contribute to the combined cost of tuition and fees at the rate in place at the time of award.

Stipend levels, as well as funding amounts for tuition and fees and the institutional allowance are announced annually in the NIH Guide for Grants and Contracts, and are also posted on the Ruth L. Kirschstein National Research Service Award (NRSA) webpage . Travel for trainees to attend scientific meetings and workshops that the organization determines to be necessary for their research training experience is an allowable expense.

Trainees must be appointed to the training grant at the time of the actual travel for this to be an allowable cost. NIGMS will provide up to $300 per trainee for travel. Plans for trainee travel should be well justified.

Training Related Expenses NIH will provide funds to help defray other research training expenses, such as health insurance, staff salaries, consultant costs, equipment, research supplies, and faculty/staff travel directly related to the research training program. The most recent levels of training related expenses are announced annually in the NIH Guide for Grants and Contracts, and are also posted on the Ruth L.

Kirschstein National Research Service Award (NRSA) webpage . Indirect Costs (also known as Facilities & Administrative [F&A] Costs) are reimbursed at 8% of modified total direct costs (exclusive of tuition and fees, consortium costs in excess of $25,000, and expenditures for equipment), rather than on the basis of a negotiated rate agreement.

NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO. Section III.

Eligibility Information Higher Education Institutions Public/State Controlled Institutions of Higher Education Private Institutions of Higher Education Nonprofits Other Than Institutions of Higher Education Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education) Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education) Indian/Native American Tribal Governments (Federally Recognized) Indian/Native American Tribal Governments (Other than Federally Recognized) U.S. Territory or Possession Native American Tribal Organizations (other than Federally recognized tribal governments) Faith-based or Community-based Organizations Eligible Agencies of the Federal Government U.S. Territory or Possession NIGMS allows multiple institutions to participate in a single MSTP application, where this may further advance the goals of the program.

A single contact institution would receive and administer the award. The sponsoring institution must assure support for the proposed program. Appropriate institutional commitment to the program should be detailed in the Organizational Support Letter in the Letters of Support attachment.

See the application instructions for the required Letters of Support instructions in Section IV. Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Applicant organizations must complete and maintain the following registrations as described in the SF 424 (R&R) Application Guide to be eligible to apply for or receive an award. All registrations must be completed prior to the application being submitted. Registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible.

Failure to complete registrations in advance of a due date is not a valid reason for a late submission, please reference NIH Grants Policy Statement Section 2. 3. 9.

2 Electronically Submitted Applications for additional information. System for Award Management (SAM) – Applicants must complete and maintain an active registration, which requires renewal at least annually . The renewal process may require as much time as the initial registration.

SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code. NATO Commercial and Government Entity (NCAGE) Code – Foreign organizations must obtain an NCAGE code (in lieu of a CAGE code) in order to register in SAM. Unique Entity Identifier (UEI)- A UEI is issued as part of the SAM.

gov registration process. The same UEI must be used for all registrations, as well as on the grant application. eRA Commons - Once the unique organization identifier is established, organizations can register with eRA Commons in tandem with completing their Grants.

gov registration; all registrations must be in place by time of submission. eRA Commons requires organizations to identify at least one Signing Official (SO) and at least one Program Director/Principal Investigator (PD/PI) account in order to submit an application. Grants.

gov – Applicants must have an active SAM registration in order to complete the Grants. gov registration. Program Directors/Principal Investigators (PD(s)/PI(s)) All PD(s)/PI(s) must have an eRA Commons account.

PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons. If the PD/PI is also the organizational Signing Official, they must have two distinct eRA Commons accounts, one for each role. Obtaining an eRA Commons account can take up to 2 weeks.

Eligible Individuals (Program Director/Principal Investigator) Any individual(s) with the skills and knowledge necessary to carry out the proposed research training program as the Training Program Director/Principal Investigator (Training PD/PI) is invited to work with their organization to develop an application for support.

For organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the SF424 (R&R) Application Guide. As described in the instructions for the Training Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) in Section IV.

2 below, NIGMS encourages multiple PDs/PIs, particularly when each brings a unique perspective and skill set that will enhance training. Note the following: To provide research training leadership for the program, at least one of the training PDs/PIs should have a record of using rigorous and transparent methods in experimental design, data collection, analysis, and reporting in a biomedical research field applicable to the program.

Additional PDs/PIs may be included to strengthen the expertise of the PD/PI team. Examples include individuals such as program directors who regularly interact with students, or individuals with expertise in education, relevant social sciences, program evaluation, mentoring, or university administration. Any of the PDs/PIs may serve as the contact PD/PI.

The contact PD/PI is expected to have a full-time appointment at the applicant organization unless extremely well-justified. If the full-time status of the contact PD/PI changes after the award, the organization must obtain prior program approval to appoint a new PD/PI or request a deviation from the full-time rule. The PD(s)/PI(s) will be responsible for: The overall direction, management, administration, and evaluation of the program.

The day-to-day administration of the program, including direct involvement with trainees. The selection and appointment of trainees to the research training program. The selection of faculty mentors for the program, assessment of mentor performance, and ensuring the program deals appropriately with substandard mentor performance.

Monitoring and assessing the program and submitting all documents and reports as required. Appointing members of the Advisory Committee (when applicable) and implementing their guidance as appropriate. This NOFO does not require cost sharing as defined in the NIH Grants Policy Statement Section 1.

2 Definition of Terms . 3. Additional Information on Eligibility NIGMS will accept only one MSTP application per institution.

Each application must be submitted by an eligible organization with a Unique Entity Identifier (UEI) and a unique NIH eRA Institutional Profile File (IPF) number. For organizations with multiple campuses, eligibility can be considered for an individual campus (for example, main, satellite, etc.) as the applicant organization only if a UEI and a unique NIH eRA IPF number are established for the individual campus .

For organizations that use one UEI or NIH IPF number for multiple campuses, eligibility as the applicant organization is determined for the campuses together. The NIH will not accept duplicate or highly overlapping applications under review at the same time per NIH Grants Policy Statement Section 2. 3.

7. 4 Submission of Resubmission Application . This means that the NIH will not accept: A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) or resubmission (A1) application.

A resubmission (A1) application that is submitted before issuance of the summary statement from the review of the previous new (A0) application. An application that has substantial overlap with another application pending appeal of initial peer review (see NOT-OD-11-101 ).

Preceptors/Mentors (Participating Faculty) The selected faculty should be active researchers in the biomedical sciences as demonstrated by recent publications and research support. When building a training team, programs should include faculty who are committed to training, mentoring, and providing safe and supportive research environments.

Programs are encouraged to build a pool of preceptors/mentors drawn from faculty at different career stages. The applicant organization will select the trainees to be supported by the research training program. It is the responsibility of the organization to establish the qualifications of the trainees before they are supported by the program.

The individual to be trained must be a citizen or a noncitizen national of the United States or have been lawfully admitted for permanent residence at the time of appointment. Additional details on citizenship, training period, and aggregate duration of support are available in the NIH Grants Policy Statement.

All trainees are required to pursue their research training full time, normally defined as 40 hours per week, or as specified by the sponsoring institution in accordance with its own policies. Appointments are normally made in 12-month increments, and no trainee may be appointed for less than 9 months during the initial period of appointment, except with prior approval of the awarding unit.

Trainees must be enrolled in a program or programs leading to a combined clinical degree and a Ph. D. (for example, M.

D. /Ph. D.

; D. O. /Ph.

D. ; D. D.

S. /Ph. D.

, etc.). Programs should limit appointments to individuals committed to careers that utilize the dual-degree. Section IV.

Application and Submission Information 1. Requesting an Application Package The application forms package specific to this opportunity must be accessed through ASSIST, Grants. gov Workspace or an institutional system-to-system solution.

Links to apply using ASSIST or Grants. gov Workspace are available in Part 1 of this NOFO. See your administrative office for instructions if you plan to use an institutional system-to-system solution.

2. Content and Form of Application Submission It is critical that applicants follow the Training (T) Instructions in the SF424 (R&R) Application Guide except where instructed in this Notice of Funding Opportunity to do otherwise. Conformance to the requirements in the Application Guide is required and strictly enforced.

Applications that are out of compliance with these instructions may be delayed or not accepted for review. All page limitations described in the SF424 Application Guide and the Table of Page Limits must be followed. Instructions for Application Submission The following section supplements the instructions found in the SF424 (R&R) Application Guide and should be used for preparing an application to this NOFO.

All instructions in the SF424 (R&R) Application Guide must be followed. SF424(R&R) Project/Performance Site Locations All instructions in the SF424 (R&R) Application Guide must be followed. SF424 (R&R) Other Project Information All instructions in the SF424 (R&R) Application Guide must be followed.

Are Human Subjects Involved: Check "No" unless the training program itself requires the trainees to