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Find similar grantsNINDS Small Business Programs (SBIR/STTR) is sponsored by National Institute of Neurological Disorders and Stroke (NINDS) of the NIH. The NINDS Small Business Program funds small business concerns to conduct innovative neuroscience research and/or development that has both the potential for commercialization and public benefit.
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# NINDS Small Business Program | National Institute of Neurological Disorders and Stroke Trastornos neurológicos en español Health Information Toggle Health Information Dropdown * Clinical Trials and Studies * Patient & Caregiver Education Funding Toggle Funding Dropdown * Preparing Your Application * Determining Your Funding Likelihood * NINDS Small Business Program * Training & Career Development Current Research Toggle Current Research Dropdown * Focus on Tools & Topics * Research Funded by NINDS * Trans-Agency Activities News & Events Toggle News & Events Dropdown PublicationsToggle Publications Dropdown About NINDS Toggle About NINDS Dropdown [](https://www.
ninds. nih. gov/funding/ninds-small-business-program) # NINDS Small Business Program The National Institutes of Health (NIH) Small Business Program is a congressionally-mandated set-aside program to encourage research and development leading to commercialization.
TheNINDSSmall Business Program is used to achieve the mission of the Institute by supporting innovative ideas at different stages of development, including applied bench research, translational research, and early-stage clinical trials. * Potential applicants should**send a brief abstract or overview of their technology at least one month before**theSBIR/STTR standard deadline. * Contact Small Business Program staff at:NINDS_SBIR@ninds.
nih. gov * Further questions? Visit our list ofNINDS Small Business FAQS.
## Learn more about the NINDS Small Business Program Compare our programs and grants View our areas of interest and NIH-wide initiatives How to prepare and submit an application NINDS SBIR/STTR funding decision process Awardees seeking collaboration or investment Resources for commercialization Applicant FAQs and resources Frequently Asked Questions Portfolio Companies selected for investor events [](https://www. ninds. nih.
gov/funding/ninds-small-business-program#mobile-menu-toggle) * Approved Initiative Concepts * Research Opportunity Announcements * About Funding[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-2) * NINDS Global Health Research Activities * NINDS Research Priorities * Types of Research Support[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-2-1-3) * Research Capacity Building for Resource Limited Institutions * Research Project Grants * Achievement Awards[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-2-1-3-2-3) * Research Program Award (R35) Recipients[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-2-1-3-2-3-3-1) * NINDS Research Program Award (R35) * Javits Neuroscience Investigator Award (R37)[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-2-1-3-2-3-3-2) * Javits Neuroscience Investigator Award (R37) Recipients * Landis Award for Outstanding Mentorship[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-2-1-3-2-3-3-3) * Landis Award for Outstanding Mentorship Recipients[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-2-1-3-2-3-3-3-4-1) * NINDS Landis Mentor Award Nomination Form * NINDS K99/R00 Pathway to Independence Award Recipients * K12 Neurosurgeon Research Career Development Program (NRCDP) Awardees * Team or Multi-Component[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-2-1-3-2-4) * Collaborative Opportunities for Multidisciplinary, Bold, and Innovative Neuroscience (COMBINE) (RM1) * Conference and Supporting Resources[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-2-1-3-2-6) * NINDS R13/U13 Guidelines * Contracts[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-2-1-3-2-7) * Find Your NINDS Program Officer * Preparing Your Application[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-3) * The Application Process[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-3-1-1) * Pre-Submission Approval R13/U13 * Determining Eligiblity[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-3-1-2) * New and Early Stage Investigators * Preparing a Budget[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-3-1-4) * Preparing a Research Plan[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-3-1-5) * Rigorous Study Design and Transparent Reporting * Writing a Research Strategy * Additional Application Elements * Data Management and Sharing Plan[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-3-1-7) * NINDS Interpretation of the NIH GDS Policy * Human Subject Clinical Trials * Biohazards and Select Agents * Submission Troubleshooting and Technology * After You Submit[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-4) * Tracking Your Application * Understanding the Review Process[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-4-1-2) * First-Level Peer Review * Scoring and Summary Statements * Second-Level Peer Review * Determining Your Funding Likelihood[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-5) * Funding Outcomes Data[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-5-1-1) * FY22 Total Extramural Research Expenditures * FY23 Total Extramural Research Expenditures * Manage Your Award[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-6) * Pre-Award[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-6-1-1) * Applications with Foreign Components * During Award[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-6-1-2) * Change in Scope or Data Sharing * Change in PI or Senior/Key Personnel * Phased and Transition Awards * NINDS Small Business Program[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-7) * Types of NINDS Small Business Grants * Small Business Frequently Asked Questions (FAQs) * Submitting a Small Business Application * NINDS SBIR/STTR Funding Decision Process * Resources for Small Business Awardees * Training & Career Development[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-8) * Choose an Award by Career Stage & Eligibility[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-8-1-1) * High School, Undergraduate, & Post-Baccalaureate * Choose an Award by Program Type[](https://www. ninds. nih.
gov/funding/ninds-small-business-program#menu--0-0-8-1-2) * Career Development Awards * Other Training-Related Programs * NINDS's Building Up the Nerve Podcast Did you find the content you were looking for?
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Last reviewed on March 26, 2026 * National Institutes of Health * Department of Health & Human Services * Freedom of Information Act [](https://ninds. buzzsprout. com/ "Listen to our podcast") National Institutes of Health (NIH) 9000 Rockville Pike, Bethesda, MD, 20892
Based on current listing details, eligibility includes: Small business concerns. Specific eligibility requirements vary by program phase (Phase I, Phase II, Direct-to-Phase II, Phase IIB, Commercialization Readiness Pilot). Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates Phase I: typically up to $225,000; Phase II: up to $1.5 million (can vary depending on specific NOFO) Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
The current target date is rolling deadlines or periodic funding windows. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.
Federal grant success rates typically range from 10-30%, varying by agency and program. Build a strong proposal with clear objectives, measurable outcomes, and a well-justified budget to improve your chances.
Requirements vary by sponsor, but typically include a project narrative, budget justification, organizational capability statement, and key personnel CVs. Check the official notice for the complete list of required attachments.
Yes — AI tools like Granted can help research funders, draft proposal sections, and check compliance. However, always review and customize AI-generated content to reflect your organization's unique strengths and the specific requirements of the solicitation.
Review timelines vary by funder. Federal agencies typically take 3-6 months from submission to award notification. Foundation grants may be faster, often 1-3 months. Check the program's timeline in the official solicitation for specific dates.
Many federal programs offer multi-year funding or allow competitive renewals. Check the official solicitation for continuation and renewal policies. Non-competing continuation applications are common for multi-year awards.
-Purpose. This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to develop, standardize, and validate new and innovative assays, integrated strategies, or batteries of assays that determine or predict specific organ toxicities (e.g., ocular, dermal, hematotoxicity, cardiotoxicity, gastrointestinal toxicity, hepatotoxicity, nephrotoxicity, ototoxicity, olfactory loss, bladder toxicity, neurotoxicity, pulmonary toxicity, endocrine toxicity, and pancreatic beta cell toxicity), resulting from both acute and chronic exposures to various chemicals, environmental pollutants, biologics and therapeutic molecules or drugs. In addition, this FOA encourages the development, standardization, and validation of new models of arthritis, convulsion, infection and shock. New approaches for high throughput toxicity screening that involves the use of molecular endpoints, computer modeling, proteomics, genomics and epigenomics and the development of virtual tissues are also encouraged as are development of 3-dimensional organ models for toxicity evaluation. -Mechanism of Support. This FOA will utilize the SBIR (R43/R44) grant mechanisms for Phase I, Phase II, and Fast-Track applications and runs in parallel with a FOA of identical scientific scope, PA-09-007, which encourages applications under the Small Business Technology Transfer (STTR) (R41/R42) grant mechanisms. Funding Opportunity Number: PA-09-006. Assistance Listing: 93.113,93.173,93.361,93.389,93.837,93.846,93.847,93.848,93.849,93.859,93.867. Funding Instrument: G. Category: ED,ENV,FN,HL.
Purpose. This Funding Opportunity Announcement (FOA), issued by the National Cancer Institute (NCI), National Institutes of Health (NIH), invites Small Business Innovation Research (SBIR) cooperative agreement applications from small business concerns (SBCs) that propose to develop new, or to improve existing application(s) of nanotechnology-based therapeutics or/and in vivo diagnostics. This FOA will specifically support pre-clinical optimization and testing of these cancer-relevant nanotechnology applications against the intended cancer type. The proposed projects must be milestone-driven and must be clearly directed toward development of an ultimate commercial product. The outcomes are expected to advance the discovery and pre-clinical optimization phase so that an Investigational New Drug (IND) or Investigational Device Exemptions (IDE) application could be submitted to the Food and Drug Administration (FDA) by the end or shortly after completion of the Phase II project period. To facilitate these steps, the NCI will assist the awardees in various ways, including the support through the NCI-sponsored Nanotechnology Characterization Laboratory. This FOA will NOT support basic research projects, studies on disease mechanisms, and clinical trials. Mechanism of Support. This FOA will utilize the SBIR (U43/U44) cooperative agreement mechanisms for Phase I and Phase II applications. Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications. The total amount awarded and the number of awards will depend upon the quality, duration, and costs of the applications received. Funding Opportunity Number: PAR-10-286. Assistance Listing: 93.393,93.394,93.395,93.396. Funding Instrument: CA. Category: ED,HL. Award Amount: Up to $150K per award.