Small Business Grants

The Small Business Innovation Research (SBIR) Program for CHIPS for America – CHIPS Metrology seeks applications from eligible applicants to explore the technical merit or feasibility of an innovative idea or technology with the aim of developing a viable product or service that will be introduced to the commercial microelectronics marketplace. This NOFO contains multiple topics on research projects for critically needed measurement services, tools, and instrumentation; innovative manufacturing metrologies; novel assurance and provenance technologies and advanced metrology research and development (R&D) testbeds to help secure U.S. leadership in the global semiconductor industry. Funding Opportunity Number: 2024-SBIR-CHIPS-01. Assistance Listing: 11.042,11.620. Funding Instrument: CA. Category: ST.

NOAA SBIR Program is sponsored by National Oceanic and Atmospheric Administration (NOAA) SBIR. The NOAA SBIR Program funds small businesses developing innovative products with strong commercial potential that align with NOAA's mission areas. High priority is given to proposals integrating NOAA Science & Technology Focus Areas like Uncrewed Systems, Artificial Intelligence, Data and Cloud Computing. This program supports the advancement of climate adaptation and mitigation technologies.

Small Business Innovation Research (SBIR) Program is sponsored by U.S. Department of Agriculture (USDA), National Institute of Food and Agriculture (NIFA). The USDA SBIR program provides competitively awarded grants to qualified small businesses for high-quality research related to important scientific problems and opportunities in agriculture that could lead to significant public benefits.

Tory Burch Fellows Program is a grant from the Tory Burch Foundation that funds women entrepreneurs seeking to scale their businesses and strengthen their leadership. Open to U.S.-resident women who own the largest stake in a for-profit business generating at least $75,000 annually, the fellowship provides $5,000 along with access to expert mentorship, networking with decision-makers, and development resources tailored to each company's specific challenges. Applicants must be 21 or older and their business must be majority women-owned (51%+) and incorporated under U.S. law. The application deadline is November 11, 2025.

SBIR SF254-D1206: Knowledge-Guided Test and Evaluation Frameworks for proliferated Low Earth Orbit Constellations is sponsored by U.S. Air Force. DOD SBIR topic SF254-D1206: Knowledge-Guided Test and Evaluation Frameworks for proliferated Low Earth Orbit Constellations. Component: U.S. Air Force. Command: SDA. Solicitation: DoD SBIR 2025.4. Phase(s): D2PII, II, SPII. Status: Pre-Release. Open date: 3/4/2026.

Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs - USDA NIFA is sponsored by USDA National Institute of Food and Agriculture (NIFA). The SBIR/STTR programs at USDA NIFA support research and development that leads to commercialization of innovative technologies. Specific topic areas relevant to forest farming and specialty crops include 'Plant Production and Protection - Biology' which supports enhancing crop production, and 'Management of Natural Resources' which aims to commercialize technologies to manage, monitor, improve, and/or protect natural resources while sustaining farm and forest productivity.

NIBIB Trailblazer Award for New and Early Stage Investigators (R21) is sponsored by National Institute of Biomedical Imaging and Bioengineering (NIBIB). This grant is for early-stage researchers to pursue projects at the intersection of engineering and the physical sciences with life sciences. It is ideal for high-risk, high-impact medical device research where preliminary data is not required.

SBIR Matching START Grant Program is a grant from MassVentures that funds Massachusetts-based startups converting SBIR and STTR research into commercial businesses and jobs in Massachusetts. The program offers a three-round structure: 16 Round 1 grants of $100,000, 7 Round 2 grants of $200,000 for top Round 1 performers, and 3 Round 3 seed capital opportunities of up to $500,000 each. Eligible applicants are Massachusetts-based small businesses that hold a federal SBIR or STTR Phase II award. Since 2012, the START Program has awarded $41.7 million to 141 companies that have collectively raised over $5.1 billion.

Department of Energy SBIR/STTR FY 2026 Phase I Release 2 is sponsored by Department of Energy. Though the deadline for Release 2 is recently passed as of March 2026, it is included for its alignment with Advanced Materials. Future cycles and 'Out-of-Cycle' supplements often cover advanced manufacturing and high-performance materials suitable for protective applications.

Colorado Energy Efficiency Business Rebate Program is a grant from the Colorado Department of Public Health and Environment that funds energy efficiency upgrades for small businesses in eligible Colorado communities. The program provides rebates for improvements such as LED lighting installations and commercial refrigeration equipment replacement. Awards are available up to $10,000 per business. Initially available in Aurora and Commerce City, with potential expansion to additional communities. Eligible applicants are Colorado-based small businesses operating in participating communities whose projects focus on qualifying energy efficiency upgrades. The program deadline was March 1, 2026.

FY26 Capacity Building Grant Program is a grant from the DC Department of Small and Local Business Development (DSLBD) that funds Certified Business Enterprise (CBE) small businesses based in Washington, DC to build organizational and operational capacity. The program supports small businesses in strengthening their business operations, competitiveness, and growth within the District's local business ecosystem. Eligible applicants are Certified Business Enterprise small businesses based in DC. Award amounts are specified in the official program notice. The application deadline was March 4, 2026. Applicants should contact DSLBD for information on future cycles.

America's Seed Fund NSF SBIR Phase I is a grant from the National Science Foundation that provides non-dilutive seed capital of up to ,000 to early-stage startups for research and development of deep technologies based on discoveries in fundamental science and engineering. Since 1977, the program has funded approximately 400 companies per year across nearly all technology areas and markets, including artificial intelligence, energy, medical devices, robotics, and semiconductors. NSF takes no equity in funded companies, allowing founders to retain full control over their team, direction, and intellectual property. Applications are evaluated based on technological innovativeness, commercial potential, and possible societal impact. Eligibility is limited to for-profit U.S. small businesses with fewer than 500 employees. The program encourages participation from first-time entrepreneurs across all 50 states and U.S. territories.

AFWERX 26.1 SBIR Phase I Open Topic is a grant from the U.S. Department of the Air Force that funds small businesses to conduct feasibility studies on innovative technology solutions that could benefit Air Force warfighters. The Open Topic serves as the primary entry point for commercial technology companies to begin working with the Department of the Air Force. Phase I awards range from $75,000 to $150,000 for a three-month period of performance, during which the small business identifies Air Force end users and customers and obtains a Customer Memorandum of intent. Successful Phase I companies may progress to Phase II or Direct to Phase II. Eligible applicants are U.S. small businesses seeking to address Air Force challenges through commercial innovation. The deadline for the 26.1 cycle was March 6, 2026.

Enabling Accessibility Fund is a grant from Employment and Social Development Canada that funds projects making workplaces and communities across Canada more accessible for persons with disabilities. The 2026 call for proposals provides between $500,000 and $1,000,000 per project for durations up to 24 months. Funded projects create opportunities for persons with disabilities to access and maintain employment, and remove accessibility barriers in Indigenous workplaces and communities. Eligible applicants include not-for-profit organizations, for-profit organizations, Indigenous organizations, and municipal and territorial governments. The application period ran from January 16 to March 12, 2026. Virtual information sessions in English and French were provided to assist applicants with the process.

Small Research Grant Program for the Next Generation of Researchers in AD/ADRD Research (R03) is sponsored by National Institute on Aging (NIA). This program supports small research projects, including pilot and feasibility studies, to improve the prevention, diagnosis, treatment, and care for Alzheimer's and related dementias. It is specifically designed to support early-stage investigators and those new to the field.

Ripple Digital Leap Forward Accelerator is a grant from Ripple/Accion Opportunity Fund that funds small business owners looking to adopt digital tools and grow their operations. Developed by Accion Opportunity Fund (AOF) with support from Ripple, this 8-week fully virtual accelerator provides expert-led sessions covering digital tools, automation, payments (including stablecoin), marketing, inventory management, HR, and financial systems. Participants also receive a personalized digital assessment and roadmap, dedicated capital preparedness support, and peer networking opportunities. Eligible applicants must have operated their business for at least one year, generate ,000–,500,000 in annual revenue, employ 1–5 staff, maintain a functioning business website and business bank account, and commit to full program participation. Upon completion, participants receive a ,000 grant.

Shophand $5K Small Business Boost Grant is a grant from Conscious Fashion Collective, in partnership with Shophand, that provides $2,500 in cash and $2,500 in technical support to help small business owners accelerate their growth. The grant is designed to support businesses looking to strengthen operations, marketing, or product development through both direct funding and access to Shophand's platform resources. Eligible applicants are small business owners across any industry. The application deadline was April 1, 2026.

FY 2026 NIST Small Business Innovation Research (SBIR) Program Phase I is an annual federal funding opportunity from the National Institute of Standards and Technology offering up to $100,000 to U.S. small businesses with 500 or fewer employees. The program supports science and technology-based firms conducting research and development in measurement science, standards, and related NIST priority areas. Applicants must have strong research capabilities aligned with topics listed in the annual Notice of Funding Opportunity (NOFO) on Grants.gov. Phase II awards are available only to businesses that successfully complete Phase I projects. The application deadline is April 1, 2026.

SBIR FY 2026 Phase I Notice of Funding Opportunity is sponsored by National Institute of Standards and Technology (NIST). The SBIR FY 2026 Phase I Notice of Funding Opportunity is a grant from the National Institute of Standards and Technology (NIST) that supports small businesses in developing innovative technologies aligned with NIST research priorities.

Digital Health (DH) Topic is sponsored by National Science Foundation (NSF) SBIR/STTR. The Digital Health topic supports entrepreneurs and startups developing innovative technologies to improve physical or mental well-being or health, enable or assist individuals to increase or regain independence and quality of life, and improve healthcare delivery. This includes technologies applying AI in healthcare, medical image analysis, personalized medicine, EHR/EMR, clinical decision support, computer-aided diagnostics, support or therapy, and smart/connected medical devices.

Digital Health (DH) Grant (NSF SBIR) is sponsored by National Science Foundation (NSF). This grant supports entrepreneurs and startups in the earliest stages of developing innovative, differentiated, and novel technologies that aim to improve physical or mental well-being or health, enable or assist individuals to increase or regain independence and quality of life, and improve healthcare delivery, including efficiency, reducing cost, or improving outcomes. Technologies in this portfolio include those applying AI in healthcare, personalized medicine, EHR/EMR, clinical decision support, and smart/connected medical devices. Specific sub-topics include Healthcare Workflow, Economics, and Delivery.

Skip's $10,000 2026 Spring Grants is sponsored by Hello Skip. Skip is offering two $10,000 grants to support entrepreneurs and small business owners. One grant is open to all eligible applicants, while the second is reserved for Skip Plus or Pro members. This is a general small business grant, but AI-focused businesses are not excluded.

Small Business Innovation Research (SBIR) Program: Plant Production and Protection (Biology) is sponsored by USDA National Institute of Food and Agriculture (NIFA). This SBIR program supports high-quality research related to important scientific problems and opportunities in agriculture that could lead to significant public benefits. The Plant Production and Protection (Biology) topic area supports research to enhance crop production and protection through biological approaches, including new methods for plant improvement, pest management, and developing new food and non-food crop plants.

2026 Pride Fund for LGBTQIA+ Business Owners is sponsored by Unknown (Mentioned on US Chamber of Commerce CO- by US Chamber of Commerce website). This fund provides $1,000 microgrants to 20 LGBTQIA+-owned small businesses across the U. S. Grant funds may be used flexibly for expenses such as operations, equipment, staffing, or growth. Finalists also receive free access to a business accelerator program.

2026 Pride Fund for LGBTQIA+ Business Owners is a grant from Founders First CDC and multiple sponsors that provides funding and business training to LGBTQIA+ entrepreneurs across the United States. The program awards a total of $25,000 in grant packages to 25 small business owners, with each finalist receiving $1,000 in flexible funding that can be applied toward equipment, operations, staffing, or growth. Finalists also gain free access to Founders First's Passport Community program and Zebra Leadership course, valued at over $3,000 combined. Eligible applicants must identify as LGBTQIA+ business owners, serve as CEO or president, operate a U.S.-based business with 2 to 100 employees, have at least one year in business, and generate annual revenue under $5 million. Full applications open April 2026 with finalists announced at a virtual press event in September 2026.

2026 Pride Fund for LGBTQIA+ Business Owners is sponsored by Not explicitly stated, but typically a foundation or corporate funder via a platform like Hello Alice. This fund provides microgrants to LGBTQIA+-owned small businesses across the U. S. The funds can be used flexibly for expenses such as operations, equipment, staffing, or growth. Finalists also receive free access to a business accelerator program.

2026 Pride Fund for LGBTQIA+ Business Owners is sponsored by Not specified (listed as part of a general small business grant overview). This fund provides $1,000 microgrants to 20 LGBTQIA+-owned small businesses across the U. S. Grant funds can be used flexibly for operations, equipment, staffing, or growth. Finalists also receive free access to a business accelerator program.

Affordable Ka-Band Metamaterial-Based Electronically Scanned Array Radar for Test and Training is sponsored by U.S. Army (Army FUZE SBIR/STTR Program). This Army SBIR topic seeks low-cost Ka-Band radar solutions through advancements in metamaterials to mimic the performance of an Active Electronically Scanned Array (AESA). This is relevant to XRComm Inc.'

Affordable Ka-Band Metamaterial-Based Electronically Scanned Array Radar for Test and Training (A254-049) is sponsored by U.S. Army (Army FUZE Small Business Innovation Research (SBIR)). This topic seeks low-cost Ka-Band radar solutions through advancements in metamaterials to mimic the performance of an Active Electronically Scanned Array (AESA) without the high cost. Software-related technologies and any other applicable advanced technologies should be analyzed and utilized.

Intuit QuickBooks & Mailchimp Small Business Hero Program is sponsored by Intuit QuickBooks and Mailchimp. Intuit QuickBooks & Mailchimp Small Business Hero Program is a grant from Intuit QuickBooks and Mailchimp that awards $20,000 to small businesses in the United States that have demonstrated exceptional courage, perseverance, and integrity in their communities.

Seeds of Sustainability Fund is sponsored by Ceiba Foundation. This fund stimulates or catalyzes projects addressing biodiversity loss, climate change, and environmental inequality in developing countries in the tropics. Preference is given to projects affecting threatened habitats and species aligning with Ceiba's conservation priorities. Ecotourism initiatives that demonstrate a clear link to biodiversity conservation and community benefit would be relevant.

Conservation Partnerships / Seeds of Sustainability Fund is a grant from Ceiba Foundation that funds biodiversity conservation and sustainable development projects in the tropics. The program supports community-led initiatives that protect ecosystems, promote sustainable livelihoods, and advance environmental stewardship in developing countries. Eligible applicants include non-profit organizations, community organizations or associations, small businesses, and individuals from developing countries in the tropics. Awards range from $1,000 to $10,000, with the 2026 application window open from April 15 to May 15, 2026.

SPARK Funding Opportunity (DE-FOA-0003580) - Topic Area 1: Grid Resilience is sponsored by U.S. Department of Energy (DOE). This grant funds grid modernization projects to accelerate the deployment of advanced transmission technologies, including reconductoring and other key upgrades, to enhance grid flexibility and improve the resilience of the power system against extreme weather.

SBIR/STTR Phase I Topics is a grant from NASA (National Aeronautics and Space Administration) that funds small businesses and research institutions to establish the scientific, technical, and commercial feasibility of innovative technologies aligned with NASA's mission priorities. Phase I serves as the idea generation phase, enabling applicants to demonstrate the merit and feasibility of their proposed innovation before advancing to subsequent development phases. NASA publishes annual solicitations — including the 2026 Appendix A SBIR and 2026 Appendix B SBIR and STTR solicitations — identifying specific technology topic areas across aeronautics, space exploration, biological sciences, flight research, manufacturing, and technology transfer. Small businesses partner with research institutions in STTR projects.

NASA SBIR 2026 Phase I Solicitation (Human Systems) is a grant from the National Aeronautics and Space Administration (NASA) that funds small businesses developing innovative technologies with strong commercial potential in the area of human space systems. NASA's Small Business Innovation Research (SBIR) program is a competitive, phased program supporting R&D with potential for commercialization, and Phase I awards establish the technical merit and feasibility of proposed research. The Human Systems focus area includes technologies supporting crew health, performance, habitation, and safety for space exploration missions. Phase I awards provide up to $150,000 in funding. Eligible applicants must be for-profit small business concerns registered in the United States. The application deadline is May 21, 2026.

Quantum Computing (SBIR/STTR) is sponsored by National Aeronautics and Space Administration (NASA). This NASA SBIR/STTR subtopic aims to develop and improve quantum, quantum-inspired, and hybrid quantum-classical workflows to demonstrate utility or advantage over existing classical algorithms for high-utility Science Mission Directorate (SMD) problems. It supports mission-aligned projects and measurable outcomes, with a focus on near-to-mid-term technology needs for leveraging quantum computing advances.

2026 Appendix A SBIR Solicitation is sponsored by National Aeronautics and Space Administration (NASA). NASA is seeking proposals for the Small Business Innovation Research (SBIR) Phase I funding opportunity under Appendix 26A. This solicitation focuses on developing innovative technologies that address specific NASA needs, requiring a clear understanding of the problem, current state-of-the-art, and a sound technical approach.

FY2026 Research Opportunities in Accelerator Stewardship and Accelerator Development is a grant from Department of Energy (DOE) Office of Science that please note that this Notice of Funding Opportunity (NOFO) is for cross-cutting R&D and domestic supplier development and that program-specific AS&T R&D is supported though NOFOs issued by each SC program. Track 1: Accelerator Stewardship Topical Areas Applications for activities in Track 1: Accelerator Stewardship Topical Areas will be accepted from all responsible domestic organizations capable of meeting the objectives of this NOFO. Colleges and universities, non-profit and for-profit research organizations, DOE's national laboratories, small businesses, and other federal research organizations. The application deadline is 2026-05-21 00:00:00+00.

NASA SBIR 2026 Phase I BAA for AI Autonomy Robotics and Intelligent Space Systems is sponsored by National Aeronautics and Space Administration (NASA). NASA's 2026 SBIR Phase I program includes AI and autonomy-focused subtopics for small businesses developing innovative space technologies. Key AI-relevant topics include Autonomous Onboard Health Management for Small Spacecraft and Distributed Systems, Fault Management Technologies for Autonomous Systems, Robotic Mobility Manipulation and Sampling for planetary exploration, and High Performance Onboard Computing.

NASA SBIR/STTR 2026 Phase I is sponsored by National Aeronautics and Space Administration (NASA). Solicitation for Phase I proposals under the 2026-2027 BAA Appendices A and B, supporting innovative technologies for NASA missions including advanced computing, AI, simulations, and quantum technologies applicable to infrastructure and modeling. Key AI-relevant topics include Autonomous Onboard Health Management for Small Spacecraft and Distributed Systems, Fault Management Technologies for Autonomous Systems, Robotic Mobility Manipulation and Sampling for planetary exploration, and High Performance Onboard Computing.

2026-2027 BAA Appendix 26B-I STTR Solicitation is sponsored by National Aeronautics and Space Administration (NASA). This STTR solicitation from NASA is for Phase I projects, encouraging cooperative R&D between small businesses and research institutions to develop innovative technologies that align with NASA's mission. Software development is a key area within STTR programs.

SBIR/STTR Program Fiscal Year 2026-2027 Broad Agency Announcement (BAA) is sponsored by National Aeronautics and Space Administration (NASA). NASA's SBIR/STTR program funds deep tech startups and small businesses for innovative research and development that aligns with NASA's mission needs. This includes areas like robotic actuation hardware for space environments, motion planning for lunar operations, and autonomous robotic software. The program supports high-impact, high-risk technologies that push innovation forward, including those related to AI.

NASA 2026 SBIR Phase I Solicitation is sponsored by National Aeronautics and Space Administration. NASA 2026 SBIR Phase I Solicitation is a grant from the National Aeronautics and Space Administration that funds early-stage research and development by small businesses on technologies aligned with NASA's missions in space exploration, aeronautics, science, and technology.

Natural Gas Distribution Infrastructure Safety and Modernization Grant Program is sponsored by Pipeline and Hazardous Materials Safety Administration. Natural Gas Distribution Infrastructure Safety and Modernization Grant Program is a grant from the Pipeline and Hazardous Materials Safety Administration (PHMSA) that funds the repair, rehabilitation, or replacement of natural gas distribution infrastructure to improve safety an…

The NEI uses UG1 cooperative agreement awards to support investigator-initiated large-scale clinical trials, human gene-transfer, stem cell therapy trials, and other complex or high resource- or safety-risk clinical trials. These projects are multifaceted and of high public health significance requiring clear delineation of study organization including roles and responsibilities and require careful performance oversight and monitoring. For purposes of this Notice of Funding Opportunity (NOFO), the proposed study must be intended to evaluate interventions aimed at screening, diagnosing, preventing, or treating vision disorders, or to compare the effectiveness of two or more established interventions. The NEI UG1-supported studies are typically funded as a group of single-component companion grant awards including the Chairs Grant, the Coordinating Center, and Resource Centers, when appropriate. Specifically, this NOFO encourages applications for the Chair's grant, which includes the scientific rationale, study aims and significance of the research project. Funding Opportunity Number: PAR-23-209. Assistance Listing: 93.867. Funding Instrument: CA. Category: HL.

2026 Pride Fund for LGBTQIA+ Business Owners is sponsored by See official notice (often via Hello Alice or similar platforms). This fund provides $1,000 microgrants to 20 LGBTQIA+-owned small businesses across the U.S., totaling $20,000 in funding. Grant funds can be used flexibly for expenses such as operations, equipment, staffing, or growth. Finalists also receive free access to a business accelerator program.

2026 Pride Fund for LGBTQIA+ Business Owners is sponsored by See official notice. The 2026 Pride Fund for LGBTQIA+ Business Owners provides $1,000 microgrants to 20 LGBTQIA+–owned small businesses across the U.S., totaling $20,000 in funding. Grant funds may be used flexibly for expenses such as operations, equipment, staffing, or growth.

2026 Pride Fund for LGBTQIA+ Business Owners is sponsored by Startup Starter (via CO— by US Chamber of Commerce). This fund provides microgrants to LGBTQIA+-owned small businesses across the U. S. Grant funds can be used flexibly for expenses such as operations, equipment, staffing, or growth. Finalists also receive free access to a business accelerator program.

Pride Fund for LGBTQIA+ Business Owners is sponsored by Founders First CDC. The Pride Fund for LGBTQIA+ Business Owners provides $1,000 microgrants to 20 LGBTQIA+–owned small businesses across the U. S. , totaling $20,000 in funding. Grant funds may be used flexibly for expenses such as operations, equipment, staffing, or growth.

Pride Fund for LGBTQIA+ Business Owners is sponsored by Hello Alice & Global Entrepreneurship Network (GEN). Pride Fund for LGBTQIA+ Business Owners is a grant program from Founders First CDC in partnership with Hello Alice and the Global Entrepreneurship Network that funds LGBTQIA+ entrepreneurs nationwide with combined cash grants and business accelerator programming.

2026 Pride Fund for LGBTQIA+ Business Owners is sponsored by Hidden Gems. This fund provides $1,000 microgrants to 20 LGBTQIA+–owned small businesses across the U. S. Grant funds can be used flexibly for expenses such as operations, equipment, staffing, or growth. Finalists also receive free access to a business accelerator program.

2026 Pride Fund for LGBTQIA+ Business Owners is sponsored by Nonprofit/Corporate Entities (exact funder not specified, but widely listed as open). The 2026 Pride Fund for LGBTQIA+ Business Owners provides $1,000 microgrants to 20 LGBTQIA+-owned small businesses across the U.S., totaling $20,000 in funding. Grant funds may be used flexibly for expenses such as operations, equipment, staffing, or growth.

2026 Pride Fund for LGBTQIA+ Business Owners is sponsored by Pride Fund. The 2026 Pride Fund for LGBTQIA+ Business Owners provides $1,000 microgrants to 20 LGBTQIA+–owned small businesses across the U.S., totaling $20,000 in funding. Grant funds may be used flexibly for expenses such as operations, equipment, staffing, or growth. Finalists also receive free access to a business accelerator program.

2026 Pride Fund for LGBTQIA+ Business Owners is sponsored by N/A (administered by CO— by US Chamber of Commerce with partners). This fund provides $1,000 microgrants to 20 LGBTQIA+-owned small businesses across the U. S. Grant funds can be used flexibly for expenses such as operations, equipment, staffing, or growth. Finalists also receive free access to a business accelerator program.

High-performance Optimized Recycled Nuclear Isotopes for Gen IV Reactors (HORNIG) is a grant from the Advanced Research Projects Agency-Energy (ARPA-E) at the U.S. Department of Energy that funds transformative research and development of recycled nuclear isotopes for use in next-generation (Gen IV) nuclear reactors. The program seeks technologies with disruptive market potential that can meaningfully advance with a modest investment over a defined period, targeting new cost and performance learning curves beyond what the private sector or DOE applied offices support. ARPA-E expects to make approximately 10 awards under this opportunity (DE-FOA-0003623), with cost-sharing required. Total estimated program funding is $50 million. The opportunity is open to any type of entity. The application deadline was May 28, 2026.

2026 Pride Fund for LGBTQIA+ Business Owners is sponsored by StartupNation (various partners). This fund provides $1,000 microgrants to 20 LGBTQIA+-owned small businesses across the U. S. Grant funds can be used flexibly for expenses such as operations, equipment, staffing, or growth. Finalists also receive free access to a business accelerator program.

The NIH Office of Research on Women's Health (ORWH) and participating NIH Institutes and Centers invite institutional career development award applications for Building Interdisciplinary Research Careers in Women's Health (BIRCWH) Career Development Programs, hereafter termed "Programs". Programs will support mentored research career development of junior faculty members, known as BIRCWH Scholars, who have recently completed clinical training or postdoctoral fellowships, and who will be engaged in interdisciplinary basic, translational, behavioral, clinical, and/or health services research relevant to the health of women and, where appropriate, the use of both sexes to better understand the influence of sex as a biological variable on health and disease. This Funding Opportunity Announcement (FOA) allows appointment of Scholars (K12) proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary clinical trial; or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development. Funding Opportunity Number: RFA-OD-24-013. Assistance Listing: 93.121,93.273,93.279,93.313,93.398,93.846,93.855,93.866. Funding Instrument: G. Category: ED,HL. Award Amount: Up to $840K per award.

Solar Energy Technologies Office Incubator Funding Opportunity is sponsored by U.S. Department of Energy (DOE) Solar Energy Technologies Office. Solar Energy Technologies Office Incubator Funding Opportunity is a grant from the U. S. Department of Energy (DOE) Solar Energy Technologies Office that funds early-stage research and development in solar energy technologies.

DoD SBIR/STTR FY 2026 Release 1 is sponsored by U.S. Department of Defense. This grant program funds small businesses developing innovative technologies to meet defense research and development needs, advance capabilities for warfighters, and grow the defense industrial base through commercialization. It operates as an umbrella solicitation with new research topics released monthly across DoD services and components, which may include areas relevant to force protection, installation security, and base airspace awareness.

NASA Space Launch System (SLS) Cubesat Opportunities on Artemis III, IV, and V Missions is sponsored by National Aeronautics and Space Administration (NASA) - Exploration Systems Development Mission Directorate (ESDMD). This opportunity provides CubeSat developers with a chance to fly their small satellites as secondary payloads on the Artemis III, IV, and V missions, supporting lunar exploration and related space technology.

Delta Health Care Services Grant Program is sponsored by U.S. Department of Agriculture Rural Business-Cooperative Service. Provides funding to address unmet health needs in the Mississippi Delta Region through cooperative efforts among healthcare professionals, institutions, and other entities to improve healthcare access and services, including potential support for transport and logistics solution…

Small Business Innovation Research Phase I is sponsored by U.S. Environmental Protection Agency (EPA). The EPA SBIR program funds small businesses developing innovative environmental technologies with commercial potential. This includes solutions addressing pollution control, circular economy challenges, PFAS destruction, and sustainable materials management. Proposals are evaluated on technical merit, commercialization potential, and impact/relevance.

Quantum Information Technologies (QT) is sponsored by NSF Small Business Innovation Research (SBIR)/Small Business Technology Transfer (STTR). This NSF SBIR/STTR topic focuses on innovations in information and communications technologies that fundamentally rely on quantum mechanical properties and interactions. This includes developing faster, more efficient, or more secure information processing and communications, with an emphasis on robustness, reliability, scalability, and practical operation. Examples include qubit generation and detection, error correction, and quantum cryptography.

Cloud and High-Performance Computing (CH) - NSF SBIR is sponsored by National Science Foundation (NSF). This NSF SBIR topic focuses on innovations that significantly improve cloud computing or high-performance computing platforms, including aspects like computing power, efficiency, and energy management, which can result from software- or hardware-based innovations, including thos…

DARPA Defense Sciences Office Office‑Wide BAA (HR001125S0013) is sponsored by DARPA Defense Sciences Office (DSO). DARPA Defense Sciences Office Office-Wide BAA (HR001125S0013) is a broad agency announcement from DARPA's Defense Sciences Office (DSO) that funds innovative basic and applied research in the physical, engineering, and life sciences with national security relevance.

Artificial Intelligence (AI) (NSF SBIR) is sponsored by National Science Foundation (NSF) SBIR. This topic focuses on cutting-edge technologies in deep learning-based AI systems and AI-based hardware. It emphasizes next-generation AI technologies that are safe, reliable, fair, robust, privacy-preserving, and efficient, including those that can improve surgical outcomes or identify mental health challenges.

Artificial Intelligence (AI) SBIR/STTR Phase I is sponsored by National Science Foundation (NSF). This NSF SBIR/STTR topic focuses on cutting-edge AI technologies that are safe, reliable, fair, robust against adversaries, privacy-preserving, and efficient. It also includes novel hardware technologies for sustainable AI, edge devices (i.e., intelligent systems on a chip for applications such as voice assistants), and AI technologies that lead to better hardware systems. The program funds high-risk, high-impact technologies with strong commercial potential.

Artificial Intelligence (AI) (SBIR Program) is sponsored by National Science Foundation (NSF). This SBIR program focuses on cutting-edge technologies in deep learning-based AI systems and AI-based hardware. It emphasizes next-generation AI technologies that are safe, reliable, fair, robust, privacy-preserving, and efficient. It also includes cutting-edge hardware technologies needed for sustainable AI and edge devices.

Cloud and High-Performance Computing (CH) SBIR/STTR Program is sponsored by National Science Foundation (NSF). This NSF SBIR/STTR program funds small businesses developing innovations that result in substantial improvements to cloud computing or high-performance computing platforms. This includes improvements in computing power, efficiency, energy management, data storage, latency, data integrity and availability, and cost, which can be software or hardware-based.

This DoD SBIR Phase I topic seeks runtime monitoring systems that detect and mitigate errors in AI-driven autonomy for unmanned aerial platforms, ensuring safe flight and mission execution. The system must identify faulty autonomous decisions in real time and trigger corrective actions to maintain operational safety. As autonomous unmanned platforms become central to Air Force operations, ensuring that AI decision-making remains reliable and recoverable during mission execution is a critical safety requirement. The runtime assurance system should monitor AI outputs against defined safety boundaries, detect anomalous autonomy behavior, implement graceful degradation when AI systems malfunction, and provide real-time logging for post-mission analysis. This technology is essential for building the trust and reliability needed to deploy autonomous systems in contested and complex environments. Part of DoD SBIR Release 26.2, this topic addresses the Air Force's need for verified and validated autonomy that can be trusted for operational deployment. Successful Phase I performers may compete for Phase II prototype development funding.

U.S. Air Force SBIR DAF26BZ01-NV003: Low-Cost is a grant from the U.S. Air Force that funds small businesses developing low-cost defense and aerospace technologies through the DoD SBIR program. This specific solicitation is part of a broader U.S. Air Force SBIR batch covering topics such as low-cost modular payload vehicles for electronic warfare swarms, low-cost phased array antennas for collaborative jamming in small UAS swarms, autonomous systems, AI frameworks, space logistics, and sensor technologies. Eligible applicants are small businesses that submit proposals through the official DoD SBIR application portal. Awards and specific funding amounts are listed in the official solicitation notice. Teams can collaborate via the DoD Team Builder tool.

DoD SBIR/STTR FY-2026 Release 1 is sponsored by Department of Defense (DoD). This is an anticipated release for DoD SBIR/STTR, with expected topics including AI security, adversarial machine learning, autonomous cyber operations, and LLM security. The program aims to stimulate technological innovation by strengthening the role of small businesses in meeting DoD research and development needs, delivering innovative technology to the Warfighter, and growing the defense industrial base through commercialization. While 'financial technology risk analytics' isn't explicitly stated, AI security and adversarial machine learning could encompass aspects relevant to financial risk in defense-related contexts.

Robocasting Ceramic Sensors - SBIR Topic DON26BZ01-NV021 is sponsored by U.S. Navy (Department of Defense). Robocasting Ceramic Sensors is a grant from the U. S. Navy (Department of Defense) under SBIR Topic DON26BZ01-NV021 that funds small business innovation research to develop additive manufacturing techniques for producing ceramic sensors with defense applications.

DOD SBIR 2026 BAA (Biological Technologies - Broadening Availability of Regimens for K-9s (BARK) - Open Topic) is sponsored by DARPA. This DARPA SBIR opportunity under the DOD SBIR 2026 BAA focuses on developing medical products that are interoperable and compatible across humans and dogs to meet the health needs of both human warfighters and military working dogs.

Small Business Technology Transfer (STTR) DPA26TZ01-NV001: Small-Robotic Swarms for Autonomous Battlefield Medical Assistance is sponsored by Defense Advanced Research Projects Agency (DARPA). This STTR topic aims to develop and demonstrate small-robotic swarms capable of autonomous battlefield medical assistance, including short casualty movement, hemorrhage control, fracture stabilization, and medication delivery. The program requires a formal partnership between a small business and a university or nonprofit research institution.

DARPA SBIR DPA26BZ01-DV004 Extremity Platform for On-demand Surgical Implantation and Tissue Integration with Osteochondral Neogenesis is sponsored by Defense Advanced Research Projects Agency (DARPA). DARPA is seeking proposals to develop an on-demand regenerative medicine platform for complete finger restoration following trauma, aiming for full functional recovery and eliminating traditional surgeries.

June 2026 Tech Talk: Friend or Fraud - How to Put AI to Work Without Getting Burned is sponsored by U.S. Small Business Administration (SBA). SBA's Tech Talk session covers the risks and benefits of AI adoption for small businesses, providing guidance on leveraging AI without falling victim to fraud.

SBIR / STTR #DAF26BZ01-NV003: Modular Payload Vehicle for Electronic Warfare Swarms is sponsored by Department of the Air Force (AFMC command). This SBIR opportunity from the Department of the Air Force (AFMC command) seeks innovative small business proposals for a low-cost modular payload vehicle to enable agile electronic warfare swarms with ground launch capability.

In-Transit Visibility (ITV) Blockchain (A254-P051) is sponsored by U.S. Army (via Army FUZE SBIR|STTR Program). This funding opportunity through the Army FUZE Small Business Innovation Research (SBIR) initiative seeks innovations for military logistics. Specifically, it drives military logistics forward with a real-time In-Transit Visibility (ITV) system by integrating blockchain technology, sensor fusion, and predictive analytics. The system should deliver enhanced transparency and efficiency in logistics operations.

AI Framework for Multimodal Scene Construction and Data Generation is a grant from the Department of the Air Force (AFWERX) that funds small businesses developing artificial intelligence solutions for multimodal scene construction and synthetic data generation in support of Air Force mission needs. Offered through the SBIR (Small Business Innovation Research) program, Phase I awards are typically up to $200,000 and Phase II awards up to $2,000,000. Eligible applicants must be U.S.-owned small businesses with 500 or fewer employees. The solicitation closed June 3, 2026. AFWERX, the innovation arm of the Department of the Air Force, has awarded over $7.24 billion across 10,400+ contracts since 2019 to accelerate technology transition from small businesses and startups into operational Defense capabilities.

AI Framework for Multimodal Scene Construction and Data Generation is sponsored by Department of the Air Force. This SBIR topic aims to develop an AI framework that generates geo-specific multimodal scenes (RF and EO/IR) using geospatial, environmental, and sensor data. This is to produce high-fidelity synthetic datasets for training autonomous systems and AI/ML models in realistic operational environments.

Navy FY26 Release 1 STTR BAA & Topics is a grant from the Department of the Navy that funds small businesses partnering with research institutions to develop innovative technologies for naval and defense applications. Released on a monthly schedule throughout fiscal year 2026, each Broad Agency Announcement (BAA) includes conventional SBIR and STTR topics, with some Direct to Phase II and Commercial Solutions Openings using Other Transaction agreements. Phase I awards are estimated at ,000. Eligible applicants are small business concerns that formally partner with a qualifying U.S. research institution. Proposals are submitted through the Defense SBIR/STTR Innovation Portal (DSIP), and a pre-release period allows direct communication with Technical Points of Contact before submissions open.

DoD SBIR 2026 BAA (DPA26BZ01-DV003: Smart Whole Blood Field Transfusion system (SWiFT)) is sponsored by Defense Advanced Research Projects Agency (DARPA). This SBIR topic seeks to develop and demonstrate a self-contained, autonomous device capable of blood collection, temporary storage, diagnostic testing, and transfusion, with continuous donor/recipient monitoring and alerts to issues, to revolutionize safe, efficient and effecti…

Novel Experiential Technologies Assisting Individual Learning Hubs (NExT AI Hubs) is sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) - NIH. This initiative seeks to advance NICHD's mission through a Centers program that will carry out research on understudied, highly innovative, and high-risk research topics related to the impact of Artificial Intelligence (AI) technologies on developmental outcomes in children at r…

DoD STTR Specific Topic 26.TZ Release 1 is sponsored by Department of the Air Force (managed by AFWERX). This Department of Defense (DoD) STTR solicitation, managed by AFWERX, focuses on specific topics for cooperative research and development. An example topic is Low-Cost, Phased Array Antennas for Collaborative Jamming in sUAS Swarms.

Medical and Pharmaceutical Waste Removal and Disposal is sponsored by Defense Health Agency (DHA). The Defense Health Agency seeks a firm-fixed-price contract for medical and pharmaceutical waste removal and disposal at Naval Health Clinic Cherry Point, North Carolina. The contractor shall furnish all personnel, equipment, supplies, facilities, transportation, tools, materials, and supervision necessary to perform the work in compliance with federal, state, and local regulations.

Standardizing Data and Metadata from Wearable Devices (R01 Clinical Trial Not Allowed) is sponsored by National Institute of Mental Health (NIMH). This funding opportunity supports the creation of standards for data and metadata from wearable devices and cell phones to promote re-use and integration of this data by researchers. The goal is to facilitate secondary data analysis and the development of software packages and workflows, which is crucial for advancing health equity research using wearable data. Applicants are expected to partner with device manufacturers and the research community.

2026 CTR Non-Proliferation Programing is a grant from the U.S. Department of State, Bureau of Arms Control and Nonproliferation that funds programming and training with foreign partners to advance national security and nonproliferation objectives. Administered by the Office of Cooperative Threat Reduction (CTR), the program supports research security, cybersecurity, and intellectual property protection training; deployment of Small Modular Reactor (SMR) technologies in strategic regions; and sanctions implementation training targeting Iran's nuclear and missile programs and proliferation networks tied to adversarial actors. Awards carry a minimum of $250,000. Eligible applicants include U.S. for-profit businesses, nonprofits, and institutions of higher education, with a deadline of June 10, 2026.

Research and Evaluation on School Safety is sponsored by National Institute of Justice (NIJ). This solicitation seeks applications for rigorous research and evaluation projects to fill knowledge gaps regarding the root causes and consequences of school violence, and to examine the impact and effectiveness of school safety approaches authorized under the STOP School Violence Act. Small businesses are eligible to apply.

Empower to Grow (E2G) – 7(j) Technical Assistance Grant Initiative is sponsored by U.S. Small Business Administration (SBA). This SBA manufacturing grant program is designed to strengthen the U.S. industrial base by funding organizations that deliver hands-on, in-person manufacturing training and technical assistance to small businesses. Food processing is specifically included as an eligible manufacturing sector, which could support a restaurant food technology startup through training and technical assistance providers.

The Biz-M-Power Crowdfunding Match Program, funded by the Massachusetts Growth Capital Corporation through the Commonwealth's operating budget, provides matching grants to small businesses in Massachusetts. Eligible businesses crowdfund between $2,500 and $20,000 on the Patronicity platform and receive a 1:1 matching grant from MGCC, potentially earning over $40,000 total. Applicants must operate a public-facing brick-and-mortar location with 1-20 employees and annual revenue under $2.5 million. The program prioritizes businesses owned by low-to-moderate income individuals and those in economically disadvantaged or Gateway City communities. Each applicant must partner with a Small Business Technical Assistance sponsor. Home-based businesses, nonprofits, franchises with more than two locations, and cannabis-related businesses are ineligible.

Grants to Virginia Small Businesses to Support Operations and Attract New Businesses to the Region is sponsored by Virginia Department of Housing and Community Development (implied). This program offers grants to Virginia small businesses in eligible locations to support operations and attract new businesses to the region, helping new companies overcome barriers to entry.

Industrial Renovation for Opportunity and New Economic Development (IRONED) Pilot Program is sponsored by Kansas Department of Commerce, Office of Rural Prosperity. This program helps rural Kansas communities revitalize underused industrial and manufacturing buildings and prepare them for new or expanding businesses. Grants support projects in the planning phase that preserve and bring new economic activity to underutilized, vacant or dilapidated industrial and manufacturing facilities, and are intended to close financing gaps.

New Generation of Glucose Control Technologies Incorporating AI/ML is a funding announcement from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at NIH that will solicit applications for research to improve open- and closed-loop diabetes control systems for Type 1 diabetes. Research priorities include innovations in analyte sensing, novel hormone formulation and delivery, AI and machine learning-driven algorithms, and digital twin modeling to enhance glycemic control and quality of life. Awards will use the R01 research project grant activity code. Applications are not yet being solicited but the notice was issued to allow potential applicants time to develop meaningful collaborations. Eligible applicants include universities, nonprofits, Tribal governments, for-profit organizations, and federal agencies.

NCATS program (PAR-25-157) supporting development of innovative technologies for translational science including AI/ML-driven drug discovery, high-throughput screening automation, computational target identification, and novel assay platforms. Funds exploratory research that creates new tools, methods, and technologies to overcome specific translational bottlenecks in the drug development pipeline. Part of NCATS' broader mission that has enabled over 45 promising new drugs to move into clinical trials through partnerships with academia, industry, and patient advocacy groups. NCATS maintains a pharmaceutical collection of nearly every human-approved drug and automated solutions for rapid drug repurposing screening including for emerging infectious diseases.

The SBA Manufacturing in America Empower to Grow (E2G) Grant Initiative is a new $50 million program announced in May 2026 to support small manufacturers across the United States. The program funds organizations that provide training, technical assistance, and workforce development to small manufacturing businesses in critical industries including advanced manufacturing, robotics, aerospace, shipbuilding, rail equipment, mining, industrial machinery, construction equipment, metal fabrication, electrical equipment, food processing, and medical/precision manufacturing. As many as 10 awards will be made to organizations with demonstrated experience providing hands-on manufacturing training and technical assistance to small manufacturers. The program addresses the need for small manufacturers — who represent 98% of all U.S. manufacturers — to adopt modern technologies including AI, automation, and advanced manufacturing processes to remain globally competitive. Three informational webinars are scheduled for May 11, May 27, and June 3, 2026. Applications must be submitted via grants.gov by June 15, 2026 at 11:59 PM EDT. Contact: e2g@sba.gov.

PNF McCall SO Lawn Services is sponsored by USDA Forest Service. This is a solicitation for lawn care services for the USDA Forest Service in the Intermountain Region. While not a typical 'grant' for business growth, it represents a direct opportunity for a lawn care business to secure a federal contract.

The DARPA Tactical Technology Office (TTO) Office-Wide Broad Agency Announcement (HR001125S0011) solicits innovative proposals for system-level defense technology research, development, and prototyping. TTO focuses on technologies that enhance rapid force building, adaptation, and sustainment capabilities for the U.S. military. Key areas of interest include autonomous platforms and swarms, AI-enabled weapons systems and battle management, unmanned aerial and ground vehicles, advanced munitions and tactical robotics, human-machine teaming for tactical operations, advanced sensors and seekers, and rapid prototyping of unmanned systems. The BAA uses a two-step process: researchers submit Executive Summaries (deadline April 17, 2026), and DARPA responds with encouragement or discouragement before inviting full proposals on a rolling basis until June 22, 2026. Award instruments include procurement contracts, grants, cooperative agreements, and Other Transactions. Small businesses and nontraditional defense contractors are specifically encouraged to apply.

Tactical Technology Office (TTO) Office Wide Broad Agency Announcement (BAA) is sponsored by Defense Advanced Research Projects Agency (DARPA). DARPA TTO is soliciting innovative executive summaries and proposals to demonstrate revolutionary defense platforms, systems, and manufacturing approaches that enhance the nation's ability to rapidly build, adapt, and sustain force structures. This includes advanced materials and manufacturing, and aerospace & spacetech.

The DARPA Tactical Technology Office (TTO) Office-Wide BAA (HR001125S0011) solicits innovative proposals for revolutionary defense platforms, systems, and manufacturing approaches. The TTO mission is to reimagine military hardware design, development, test, manufacture, and sustainment with a focus on rapid, affordable, and scalable deployment. Three focus areas are targeted: Design/Build/Buy (disrupting systems engineering and acquisition processes), Long Range Effects (enabling decisive military effects at tactical to strategic distances), and Disruptive Innovation (rapidly fielding novel engineering approaches that disrupt the battlefield). The Disruptive Innovation area specifically includes low-cost autonomous systems that use mass to overwhelm defensive systems, making this highly relevant for AI-driven autonomy and robotics companies. This BAA is distinct from DARPA's DSO and I2O office-wide BAAs which focus on basic science and information innovation respectively. TTO focuses on operational technology demonstrations and system prototyping.