NIH R01 Research Project Grant
Quick Facts
- Agency
- NIH
- Funding
- Up to $500,000 per year
- Deadline
- June 15, 2026 (127 days remaining)
- Status
- Active
- Eligibility
- Higher education institutions; Nonprofits with 501(c)(3) status; State and local governments; Small businesses; Independent research organizations
About This Grant
The Research Project Grant (R01) is the original and historically oldest grant mechanism used by NIH. The R01 provides support for health-related research and development based on the mission of the NIH. R01s can be investigator-initiated or can be solicited via a Request for Applications.
View Original RFPEligibility Requirements
- Higher education institutions
- Nonprofits with 501(c)(3) status
- State and local governments
- Small businesses
- Independent research organizations
Related Grants
Small Business Innovation Research (SBIR) Program - Biomedical Product Development
Supports small businesses developing innovative biomedical technologies, including implantable drug delivery devices for cardiovascular, pulmonary, and related applications. Phase I funds proof-of-concept; Phase II scales development.
Small Business Technology Transfer (STTR) Program - Drug Delivery Technologies
Funds collaborative R&D between small businesses and research institutions for implantable and bioengineered drug delivery systems to improve therapeutic delivery precision and patient outcomes.
Small Business Innovation Research (SBIR) - NIAID Drug Delivery Systems
Supports development of implantable devices for sustained drug release to combat infectious diseases, with emphasis on long-term delivery efficacy.
NIH Grant Writing Tips
What NIH Reviewers Wish You Knew
Insider tips from NIH reviewers on what they prioritize in grant proposals. Specific Aims, preliminary data, and pitfalls to avoid.
Read articleTips for a Successful NIH SBIR Resubmission: Learning from Feedback and Improving Your Proposal
Rejected SBIR proposal? Good — now you have reviewer feedback. Use it to address weaknesses, sharpen your aims, and resubmit stronger.
Read articleThe Reasons Most NIH R01 Proposals Fail
Why most NIH R01 proposals fail and how to fix common mistakes. Avoid unclear aims, weak methodology, and insufficient preliminary data.
Read article