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The Department of State’s Office of the Nonproliferation and Disarmament Fund (ACN/NDF) is pleased to announce an open competition for assistance awards through this Notice of Funding Opportunity (NOFO). ACN/NDF invites domestic non-profit/non-governmental organizations, educational institutions, and for-profit organizations to submit proposals for projects that will advance the mission of NDF’s efforts to identify, evaluate, and develop safeguards to counter the misuse risks enabled by the proliferation of chemical and biological Artificial Intelligence (AI) models (CBAIMs). Proposals may not exceed the total availability of funds under this NOFO. ACN/NDF welcomes proposals that fully address all or a clearly articulated, targeted subset of the key objectives of this NDF line of effort (Section II). Please indicate whether the proposal involves collaboration with a partner organization that is separately responding to this solicitation.
Funding Opportunity Number: DFOP0018449. Assistance Listing: 19.224. Funding Instrument: CA,O. Category: ST. Award Amount: Up to $4M per award.
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Or search similar grants →According to the current listing, eligibility includes: Eligible applicants: Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; For-profit organizations other than small businesses; Small businesses; Others (see text field entitled Additional Information on Eligibility for clarification). U.S. Federal Government Entities. Lead applicant organizations must be based in the U.S. to be eligible. Confirm the full requirements in the official notice before applying.
The current listing shows up to $4M per award. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Applications for Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities are due July 21, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
Yes — Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities is offered by Bureau of Arms Control and Nonproliferation and this listing comes from Grants.gov, an official U.S. federal source. Federal applications generally require registrations (for example SAM.gov or an agency submission portal), so allow extra lead time.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities is sponsored by U.S. Department of State's Bureau of Arms Control and Nonproliferation. Supports projects to identify and develop safeguards against the misuse of AI-enabled chemical and biological molecular models, aiming to reduce proliferation risks and explore nonproliferation opportunities.
Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities is sponsored by Department of State's Office of the Nonproliferation and Disarmament Fund (ACN/NDF). This NOFO invites proposals for projects that will advance the mission of NDF's efforts to identify, evaluate, and develop safeguards to counter the misuse risks enabled by the proliferation of chemical and biological Artificial Intelligence (AI) models (CBAIMs).
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