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Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional) is sponsored by National Institute of Environmental Health Sciences (NIEHS) - NIH. This multi-project center grant supports research and training focused on hazardous substances.
The program is specifically interested in proposals applying new engineering, materials science, and biotechnology approaches to remediation and detection of hazardous substances.
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Limited Competition: Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional) Department of Health and Human Services National Institutes of Health Document Type:Grants Notice Funding Opportunity Number:RFA-ES-27-004 Funding Opportunity Title:Limited Competition: Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional) Opportunity Category:Discretionary Opportunity Category Explanation: Funding Instrument Type:Grant Category of Funding Activity:Health Expected Number of Awards:10 Assistance Listings:93.
143 -- NIEHS Superfund Hazardous Substances_Basic Research and Education Cost Sharing or Matching Requirement:No Last Updated Date:May 19, 2026 Original Closing Date for Applications:Sep 25, 2028 Current Closing Date for Applications:Sep 25, 2028 Archive Date:Nov 24, 2028 Estimated Total Program Funding:$ 22,000,000 Eligible Applicants:Private institutions of higher education Public and State controlled institutions of higher education Additional Information on Eligibility:Based on 42 USC 9660(a)(3) eligible applicants are limited to accredited institutes of higher education.
Eligible applicants are permitted under the law, and encouraged by NIEHS, to subcontract as appropriate with other organizations as necessary to conduct portions of the research.
Examples of other organizations may include generators of hazardous wastes; persons involved in the detection, assessment, evaluation, and treatment of hazardous substances; owners and operators of facilities at which hazardous substances are located; and/or State and local governments. Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.
Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
## Additional Information Agency Name:National Institutes of Health Description:The National Institute of Environmental Health Sciences (NIEHS) is announcing the continuation of the Superfund Hazardous Substance Research and Training Program, referred to as Superfund Research Program (SRP) Centers.
SRP Center grants will support problem-based, solution-oriented research Centers that consist of multiple, integrated projects representing both the biomedical and environmental science and engineering disciplines; as well as cores tasked with administrative (which includes Center leadership, data management, and training); translational research and engagement; and research support functions.
The scope of the SRP Centers is taken directly from the Superfund Amendments and Reauthorization Act of 1986, which limits competition for this program to accredited institutes of higher education. Please see Section III. Eligibility for additional information.
In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding. Link to Additional Information:[](https://www. grants.
gov/search-results-detail/359650) Grantor Contact Information:If you have difficulty accessing the full announcement electronically, please contact: Hazardous Substances Research Branch National Institute of Environmental Health Sciences NOFO. Information@niehs. nih.
gov ## Similar Opportunities (identified by AI)
According to the current listing, eligibility includes: Universities, other research organizations, and small businesses are eligible. Confirm the full requirements in the official notice before applying.
Applications for Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional) are due September 25, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional) is funded by National Institute of Environmental Health Sciences (NIEHS) - NIH. Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Superfund Research Program (SRP) "Hazardous Substances Remediation and Detection Program" Small Business Innovation Research Grants (SBIR R43, R44) is sponsored by National Institute of Environmental Health Sciences (NIEHS) - NIH. This program supports Small Business Innovation Research (SBIR) grants to commercialize novel, cost-competitive technologies, products, and devices for remediation and detection of hazardous substances in the environment. It is interested in proposals applying new engineering, materials science, and biotechnology approaches, as well as sustainable and resilient remediation strategies.
Individual Research Grants (R01) - Superfund Research Program is sponsored by National Institute of Environmental Health Sciences (NIEHS) - NIH. These grants are awarded for individual research projects focusing on specific issues that complement multiproject program grants within the Superfund Research Program. The program seeks to understand how environmental exposures affect biological systems and human health.
NCI Continuing Umbrella of Research Experiences (CURE) Academic Career Excellence (ACE) Award (K32) is a grant from the National Cancer Institute (NCI) that funds early postdoctoral fellows from diverse backgrounds, including underrepresented groups, to pursue research training in cancer-related fields. The K32 award supports fellows within 12 months prior to transitioning into, or within the first two years of, a postdoctoral position. The program, operated through NCI's Center to Reduce Cancer Health Disparities (CRCHD), aims to enhance the pool of qualified diverse cancer researchers. Beginning with the June 12, 2025 due date, the CURE ACE Award is available in both Independent Clinical Trial Required and Independent Clinical Trial Not Allowed versions. Eligible applicants must be U.S. citizens or permanent residents at time of award.
Innovation Grant is a grant from the Delta Dental of Arizona Foundation that funds nonprofit organizations pursuing unique, high-impact projects that improve health and wellness in Arizona communities. This two-year award supports original initiatives with measurable real-world impact, including programs serving underserved and uninsured populations through oral health education, disease prevention, and nutritional access. Projects must demonstrate the potential to make a meaningful difference in the community and stand apart from conventional approaches. Eligible applicants are Arizona-based nonprofit organizations. Awards total $100,000 per recipient over two years. The 2026 application cycle closed October 16, 2025, with recipients notified in late 2025 and funding made available shortly after.
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