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Find similar grantsAcademic Clinical Trials Program (ACT) is sponsored by Blood Cancer United. Funds investigator-initiated clinical trials addressing unmet medical needs in blood cancer.
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m. ET) # Academic Clinical Trials Program (ACT) [](https://bloodcancerunited. org/research/grants/academic-clinical-trials-program-act) ## The Academic Clinical Trials (ACT) 2025/2026 cycle is currently closed.
Thank you for your submissions. Since 2022, the Academic Clinical Trial grants fund investigator-initiated clinical trials (IITs) that address unmet medical needs in blood cancer, recognizing that academic research may address clinical benefit needs that sometimes diverge from commercial development pathways.
The goal of this clinical award is to address unmet medical needs by testing new treatments, exploring expanded uses for existing therapies, and optimizing innovative treatment approaches in patient care. **Find out more about the application process or browse resources for current awardees below. ** #### Apply to the Academic Clinical Trials Program ### The Academic Clinical Trials (ACT) Program is now closed.
The Blood Cancer United ACT initiative is an investigator-initiated clinical trial program designed to address unmet medical needs by testing new treatments, exploring expanded uses for existing therapies, and optimizing innovative treatment approaches in patient care. These awards will fund clinical trials, up to $1M USD over a period of up to three years.
In this round, Blood Cancer United has formed a partnership with Rising Tide Foundation for Clinical Cancer Research for co-funding of ACT grants. The primary focus will be Phase 1 or 2 trials positioned to begin enrolling patients within 3-6 months of the July 1, 2026, award start. Trials should focus on one of the areas of potential interest (below).
#### Examples of projects of potential interest include: * Precision medicines engaging new targets, given as monotherapy or in combination (e.g. small molecules, monoclonal and bispecific antibodies, ADCs, RNAs or novel modalities may be prioritized) * Novel immunotherapy approaches * Therapies targeting the tumor microenvironment * Biopharmaceutical approaches in premalignant conditions for the prevention or early intervention of disease * Personalized medicine approaches for blood cancers, including novel companion diagnostics that may identify optimal treatment sub-populations * Best-in-class trials that may impact standard of care * Enhanced safety and/or efficacy of stem cell transplantation We welcome proposals that include new clinical trial designs, decentralized trial approaches and emerging technologies including AI for improved clinical trial conduct in blood cancer.
FY26 ACT Guidelines and Instructions (PDF) #### Highlights of the LOI and application process * A **Structured Clinical Abstract** at the **LOI stage** will provide succinct information about the objectives, expected outcomes, and clinical significance of the proposed study. * A **Patient Involvement Plan Summary** is required at the **LOI stage**(2 pages and a table). A full plan is required at the **Full Application** phase.
Patient engagement activities help assure that patients’ needs (both unmet medical needs and first-hand experiences) are reflected in the design of the clinical trial. * **Applicants will provide an IRB approval date OR a scheduled IRB review date** at both the **LOI stage** and in the **Full Application**. An application may be submitted with IRB approval pending, but an award will not be made without documented IRB approval.
Projects that can begin near or on the specified Award Start Date of July 1, 2026 may be prioritized. * Budget submitted should reflect the actual needs of the project but cannot exceed $1M USD in total for up to three years of the grant. * This budget ceiling includes all costs associated with the grant including indirect costs (often referred to as Institutional Overhead), which will be capped at 15% of the total award.
* Please refer to the Guidelines and Instructions document above * Apply Here: https://bloodcancerunited. fluxx. io/ * Is this your first time applying for a Blood Cancer United Research grant?
You can get started by requesting a new account. * Please reach out to researchprograms@bloodcancerunited. org with any questions.
* See the table below for all the key dates and deadlines: #### 2025-2026 application key dates According to the ACT Guidelines and Instructions, since October 13, 2025, is a federal holiday, the deadline is extended to the next business day: Tuesday, October 14, 2025, at 3:00 PM EST.
## MEET SOME OF OUR RECENT GRANTEES ### Pilot trial of microbial targeting to prevent myeloma #### Madhav Dhodapkar, MBBS ### Targeting mutant IDH2 in angioimmunoblastic T-cell lymphoma #### Zachary Epstein-Peterson, MD _Memorial Sloan Kettering Cancer Center_ ### NK cell immunotherapy to reduce relapse after haploidentical transplant for high-risk pediatric AML #### Todd Fehniger, MD PhD _Washington University in St.
Louis_ ### Do you have any questions? Please refer to the downloadable Guidelines and Instructions document above for answers and for contact information. Or contact researchprograms@bloodcancerunited.
org for any questions not answered in the Guidelines and Instructions The Leukemia & Lymphoma Society (LLS) is now Blood Cancer United. Learn more. ### Get connected, stay informed ### Call an Information Specialist Highly trained oncology social workers and nurses.
(Monday–Friday 9 a. m. –9 p.
m. ET) Your donation supports groundbreaking research and vital patient services. (Monday–Friday 9:30 a.
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ET) * Financial transparency and independence * _*Bilingual content/Contenido bilingüe_ * [](https://www. facebook. com/BloodCancerUnited) * [](https://instagram.
com/bloodcancerunited/) * [](https://x. com/BloodCancerUtd) * [](https://www. linkedin.
com/company/bloodcancerunited) * [](https://www. tiktok. com/@bloodcancerunited) * [](https://www.
youtube. com/@BloodCancerUnited) * [](https://www. threads.
com/@bloodcancerunited) * [](https://bloodcancerunited. org/blog) The Blood Cancer United mission: Cure blood cancer and improve the quality of life of all patients and their families. Blood Cancer United funds lifesaving blood cancer research around the world, provides free information and support services, and is the voice for all blood cancer patients seeking access to quality, affordable, coordinated care.
Blood Cancer United is a 501(c)(3) organization, and all monetary donations are tax deductible to the fullest extent allowed by tax laws. Please check with your financial advisor if you have more questions. Tax Identification Number: 13-5644916
According to the current listing, eligibility includes: Nonprofit organizations, academic institutions, and research entities. Confirm the full requirements in the official notice before applying.
Academic Clinical Trials Program (ACT) is funded by Blood Cancer United. Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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