Accelerated Translational Incubator Pilot (ATIP) Grant Program

Accelerated Translational Incubator Pilot (ATIP) Grant Program is sponsored by University of Maryland, Baltimore (UMB) Institute for Clinical and Translational Research (ICTR). This program provides starter funds for innovative, translational research that involves multi-disciplinary and inter-disciplinary collaborations among faculty from various UMB schools, UMBC, and UMCP.

ATIP Grant Program FOA - Institute for Clinical & Translational Research Institute for Clinical & Translational Research Note from T4's documentation: In versions prior to 8. 4. 1 you must also include the T4 tag in a comment alongside the anchor Helper.

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--> Upcoming ICTR Pilot Grant Information Session The UMB ICTR is hosting an information session for the upcoming 2027-2028 pilot grant funding opportunity on Monday, October 5, 2026 at 12:30-1:30pm. Register for this information session. Note from T4's documentation: In versions prior to 8.

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--> 2027 - 2028 Accelerated Translational Incubator Pilot (ATIP) Grant Program Funding Opportunity The University of Maryland, Baltimore (UMB), Institute for Clinical & Translational Research (ICTR) is pleased to announce the UMB ICTR Accelerated Translational Incubator Pilot (ATIP) Grant competition to provide funds for projects focused on innovative, translational research that involve faculty from the UMB Schools of Dentistry, Graduate Studies, Law, Medicine, Nursing, Pharmacy, or Social Work; and UMBC or UMCP.

Applications including collaboration between UMB and partner institution(s) (UMCP, UMBC) will be especially encouraged. See Eligibility section . Award: Up to $50,000 in direct costs (indirect costs not allowed) Funding is internally provided through the PI and Co-PI’s respective institutions.

Routing through the research administration office is not required. Funding Period: May 1, 2027 – April 30, 2028; Awardees Announced 1st Quarter 2027 View Application Deadlines .

This Request for Proposals provides funding for one of two types of ATIP opportunities : ICTR Innovative Collaboration Pilot Grant Aims to stimulate innovative collaborations among faculty of the UMB Schools and UMBC or UMCP that will involve research along the translational continuum.

ICTR Artificial Intelligence/Cybersecurity/Machine Learning Pilot Grant Aims to support new or existing clinical and translational research collaborations among faculty of the UMB Schools and UMBC or UMCP that will test transformative projects that improve healthcare.

The award aims to accomplish the following objectives: To promote innovative translational research by providing pilot grants to support projects specifically focused on the translation of laboratory and/or clinical research into new interventions that improve clinical outcomes (e.g., new diagnostics or approaches to prevention/ treatment, or implementation of new advances within communities to improve health in Baltimore and throughout the state of Maryland).

To utilize a milestone-driven approach for proposed projects that will ensure timely generation of tangible products and outcomes within the strict funding period and the approved budget. To promote cross-disciplinary collaborative research (specifically across or within UMB Schools, UMBC, and UMCP). To support investigators in the effective attainment of translational milestones by providing guidance and access to UMB ICTR resources.

To generate pilot data for innovative research projects that will foster or support subsequent major external funding applications. For questions regarding application guidelines or eligibility, please email the UMB ICTR Navigator. Additional information is provided in the sections below.

ATIP Grant Program Guidelines Note from T4's documentation: In versions prior to 8. 4. 1 you must also include the T4 tag in a comment alongside the anchor Helper.

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--> Information Session: Monday, October 5, 2026, 12:30-1:30 pm (EST). Register for the Information Session. Intent to Apply Deadline: Friday, October 16, 2026, 5:00 pm (EST).

Application Deadline: Friday, November 6, 2026, 5:00 pm (EST). Note from T4's documentation: In versions prior to 8. 4.

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1. --> Any faculty member with >50% appointment at the level of Assistant Professor, Associate Professor, or Professor from the UMB Schools of Dentistry, Graduate Studies, Law, Medicine, Nursing, Pharmacy, or Social Work; and UMBC or UMCP is eligible to apply as a Lead Principal Investigator (PI) or serve as a Co-PI for an ICTR ATIP Grant. UMBC or UMCP Lead Principal Investigators (PIs) must name a UMB Co-PI .

Research Associates, Instructors, Affiliates, Adjunct or visiting faculty are not eligible to apply. Multi-PI applications are allowed – limit to 1 Lead PI (the applicant) and 1 Co-PI. A Multiple PI leadership Plan describing the respective roles must be included with the application.

The Lead PI will serve as the point of contact for communications. A Lead PI or Co-PI (if applicable) responding to this 2027-2028 ATIP grant opportunity cannot serve as a Lead or Co-PI on another application in this round or the 2027-2028 CEnR pilot grant opportunity. However, the Lead PI and Co-PI (if applicable) may serve as a non-PI collaborator on other proposals if there is no scientific overlap.

Research Associates/Instructors/Adjunct/Affiliate/Visiting Faculty, undergraduates, graduate students, and postdoctoral fellows cannot be listed as Co-PIs or Co-Investigators. However, they may be listed in other roles in the proposal. Eligible submissions are strongly encouraged to include multidisciplinary collaborations among faculty from at least 2 of the UMB Schools/Departments or between faculty from a UMB School and UMBC or UMCP.

Eligible submissions must include a timeline of one or more milestones for each Specific Aim with clear outcome endpoints. The timeline must be feasible within the strict funding period and approved budget . Regulatory submissions/approvals and preparation of manuscript/grant application should NOT be included in the timeline since they are not considered a milestone.

Regulatory approval must be obtained before the project is allowed to start and receive funds. A proposal that is ancillary to an existing grant that adds new specific aims that could successfully leverage a new award or renewal are eligible. However, proposals to supplement existing grants are not eligible.

The project must have an Institutional Review Board (IRB) and/or Institutional Animal Care and Use Committee (IACUC) submission independent of the parent protocol with a title that matches this submission . Lead PIs and Co-PIs with a previously funded ICTR pilot grant award (ATIP or CEnR) may apply as a Lead PI or Co-PI if the previous project has been completed and there is no scientific overlap with this application.

Applications must demonstrate alignment with broadly accepted public research goals and be responsive to evolving state and federal focus areas, including compliance with current funding landscapes and policy expectations.

Applicants resubmitting a previous proposal that was not selected for an award must submit an accompanying cover letter describing how the current proposal differs from the original and how the reviewers’ comments are addressed. Anyone holding a faculty-level position who receives an ICTR ATIP grant award agrees to serve as a reviewer for at least one future Pilot Grant cycle. Note from T4's documentation: In versions prior to 8.

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4. 1. --> Institutional Regulatory Requirements/Approvals and Training Projects receiving a notice of award should plan to have ALL required regulatory approvals and other supporting documents prior to May 1, 2027 .

If the required regulatory approvals are not obtained by October 31, 2027, the project will be considered ineligible to remain in the current cohort and will be automatically deferred to the following year’s cohort — pending fulfillment of all regulatory requirements.

Human Subjects Research (HSR) IRB Letter of Determination/Approval or other supporting documents that may be needed for a project are not required at the time of the pilot grant application submission; however, the IRB submission time-burden may be significant, so applicants are strongly encouraged to begin this process early .

The IRB designation/approval letter must match the ATIP proposal, and the IRB PI must match the Lead PI or Co-PI’s name. The application team list and IRB team list must match . Review the UMB IRB website for required training of UMB and non-UMB team members engaged in research.

UMBC and UMCP applicants should contact their respective IRBs for information on other training requirements for research conducted at UMBC, UMCP, and/or UMB. If research activities are split across sites, consider the need for an IRB reliance letter. A Data Use Agreement (DUA) or Data Transfer Agreement (DTA) may be required as well as data storage in the UMB Secure Research Environment (SRE) .

For projects planning to use University of Maryland Medical System (UMMS) data, email eda-research@umm. edu due to strict data use requirements. The DUA or DTA approval process can be lengthy, and your proposal may not be feasible for this funding opportunity given the strict funding timeline .

If the HSR project is a clinical trial, the protocol must also be registered in ClinicalTrials. gov . Visit UMB’s IRB website for information about registration requirements for UMB researchers.

If your proposal requires other supporting documents, such as FDA approval, Biosafety registrations, Clinical Engineering clearance of devices, Radiation Safety registration, etc., these must be obtained prior to initiating any research activities for which the certification/registration/approval is required.

Although final IACUC approval and other supporting documents are not required at the time of the pilot grant application submission, applicants are strongly encouraged to begin the submission process early . Projects receiving a notice of award should plan to have ALL required regulatory approvals and other supporting documents prior to the start date, May 1, 2027 .

Awarded projects proposing research that involves live vertebrate animals must have the research approved by the Institution’s IACUC. The PI on the IACUC letter must match the Lead PI’s or Co-PI’s name and the IACUC title must match the ATIP project title .

If the project is conducted under the umbrella of another IACUC approval, the PI of that lab must submit an amendment to include the scope of work to be conducted for the ATIP project. The IACUC amendment approval letter must include the name of the ATIP project’s Lead PI or Co-PI and the title of the ATIP project.

Examples of Other Supporting Documents that may be required: Biosafety registrations, Clinical Engineering clearance of devices, Radiation Safety registration, etc. Note from T4's documentation: In versions prior to 8. 4. 1 you must also include the T4 tag in a comment alongside the anchor Helper.

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--> Conflicts of Interest (COI) At the time of application, review process, before funds are awarded, and throughout the project period, it is the responsibility of the awardee and all members of the study team to report any financial or fiduciary interests that might appear to present a conflict of interest (COI). These interests must be reported to the ICTR and the COI Officer, Institution’s Research Integrity Office.

The presence of a COI does not automatically disqualify investigators from receiving this award but will require the review and management of this conflict by the COI Officer. The failure of any member of the study team to disclose all outside interests could result in the termination of the award and may require repayment of study expenditures.

Information about UMB ’s COI Policy, including examples of what constitutes an outside interest, is available on the UMB Office of Accountability and Compliance, Conflict of Interest webpage ; Information about UMBC ’s COI Policy is available on the UMBC Office of Research Protections and Compliance webpage ; Information about UMCP ’s COI Policy is available on the University of Maryland Policy on Conflict of Interest and Conflict of Commitment webpage.

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--> Projects may cover a wide range of topics, including but not limited to the representative topics below. Proposals should consider alignment with the current administration’s science and innovation goals as outlined in federal research initiatives and public funding frameworks.

Development of pre-clinical research applications such as novel drug treatments platforms, therapies, or drug targets for diseases and symptoms associated with disease or treatment Methods for generation of novel vaccines or peptides Animal models for drug selection Preclinical toxicology markers/assays Surrogate marker assays, including genomic, proteomic assays, and metabolic imaging methods Key research activities that will result in new or the improvement of existing intellectual property.

Development of clinically relevant applications Development and verification of surrogate marker assays Identification of disease or symptom biomarkers Clinical trial design paradigms (e.g., computer simulation) Development or evaluation of diagnostic tests Clinical trials including Pilot/Phase 0 or 1 trials Collection of pharmacokinetics/pharmacodynamics data Clinical physiology and mechanisms/pathophysiology of disease Use of machine learning (ML) and artificial intelligence (AI) to identify patterns in data to improve healthcare delivery with minimal human intervention Develop apps and devices that improve delivery and exchange of health information Post-Clinical Translation Comparative effectiveness of research studies Knowledge transfer to providers or community Tests of innovative implementation strategies to optimize uptake of solutions at the community level Note from T4's documentation: In versions prior to 8.

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4. 1. --> Funding will be for May 1, 2027 – April 30, 2028.

Requests must be no more than $50,000 in direct costs. Budget requests must be realistic and well-justified in the budget justification. The award may be reduced if budget items are not well-justified.

Routing through the research administration office is NOT required . Required regulatory approvals and agreements, as well as other supporting documents, must be obtained prior to disbursement of funds. See Institutional Regulatory Requirements/Approvals and Training above.

Funds will be distributed in two disbursements, with the second disbursement contingent upon submission of a satisfactory progress report and appropriate spending at 6 months. Multi-Institutional Budgets (UMB, UMBC, UMCP): With multi-institutional budgets, a PI at each institution is required (see Multiple PI Leadership Plan ); Each participating institution will contribute funds as allocated in the approved budget.

Once awarded, these funds are not transferrable and cannot be used to cover expenses for the other institution; The budget must be allocated across both institutions such that each institution contributes a minimum of one-third of the total budget. See Comprehensive Budget/Detailed Budget Justification under Application Process.

Allowable expenses include: No more than $5,000 of the total budget can be allocated towards faculty salary and fringe support.

Faculty-level team members on more than one application cannot exceed the $5,000 salary limit across all projects; Equipment (total equipment costs should be no more than 20% of the budget); Recruitment and compensation of study participant costs; Payments to an outside partnering organization, where appropriate, may be considered as a “service provider” expense (not as a sub-award).

This expense must be justified and itemized under “Equipment/Supplies/Services” in the budget template form. However, funding for faculty from other University System of Maryland (USM) institutions must be included in the $5,000 total faculty salary funding limit as noted above; ATIP funds up to $1,000 may be used for travel for the conduct of the research.

ATIP funds CANNOT be used for travel to present results at meetings or conferences ; Official quotes from service providers/vendors, supplies, and/or equipment must be included; External Vendors: For UMB expenses, strong justification is required for choosing external vendors over UMB campus cores of services.

Expenses for external vendors cannot exceed $10,000; The Budget template must detail expenses per institution and include the Budget Justification for each expense, including salary.

Unallowable Expenses Include: Indirect costs cannot be included in the budget; Alterations or renovations of laboratory space; Laboratory or office furniture; Professional societies membership dues; Travel to present research results at meetings or conferences. For questions or concerns about funding restrictions, please reach out directly to the ICTR Navigator . Note from T4's documentation: In versions prior to 8.

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4. 1. --> Lead PIs and Co-PIs (if applicable) of all funded projects must provide a milestone update at three, six, and nine months from the May 1, 2027, start date.

The six-month meeting will be conducted virtually. Depending on the project's progress, the three and nine-month meeting may also be virtual or replaced by a request for a brief, written update at the discretion of the ICTR Navigators.

A written report on the progress of the milestones and budget expenditures will be required at the sixth-month time period and a final, written progress report will be due within 30 days of the end of the award period. Failure to attend milestone updates and submit progress reports in a timely manner can have significant implications for the project and may result in termination of the award.

Following completion of the project, awardees will be invited to present their project outcomes to the ICTR leadership and pilot grant cohort. Semi-annual Reporting - Please note that the ICTR will also send a semi-annual request for updates on subsequent grant applications/awards, publications, and intellectual property disclosures resulting from the project.

Understanding that it may take some time for a project to reach its full potential, these semi-annual updates will be requested for several years. Publications resulting from ICTR supported pilot grants and reported in the semi-annual report will be considered for ICTR annual publication awards towards future publication costs. Note from T4's documentation: In versions prior to 8.

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4. 1. --> Applications are submitted electronically.

To request an application link, please complete an Intent to Apply Form by Friday, October 16, 2026, 5 p. m. (EST.)

Once your request is submitted and approved, you will receive an ICTR-Navigator@umaryland. edu email with a REDCap link to the application. Please email the ICTR Navigator if you do not receive a response within 3 business days.

Any required templates will be included in the email with the application link. Please make sure to submit the Intent to Apply form in time to allow for a complete application submission. Incomplete applications or applications not responsive to this funding opportunity announcement will not be reviewed.

Prepare each of the sections below and submit the electronic application hosted within the UMB REDCap system. See Formatting Guidelines for formatting requirements. Completed applications must be submitted by Friday, November 6, 2026, 5:00 pm (EST).

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--> The Cover Letter is limited to one page and must include the following: Title of Project: The project title must match the title of the IRB or IACUC approval letter. Funding Mechanism: Indicate whether application is for the ATIP Innovative Collaboration Pilot Grant or the Artificial Intelligence/Cybersecurity/Machine Learning Pilot Grant.

Investigators: List the names, academic ranks, and appointments of the designated primary (Lead) PI and one Co-PI (if applicable) and any faculty member to receive financial support. Lead PI name must match the PI on the IRB letter. Faculty Salary Support: Specify the salary and fringe support amounts requested for each faculty-level team member listed on the grant.

The combined faculty salary and fringe support requested across all faculty-level team members cannot exceed $5,000. Required Signatures: Include the signature of Lead PI, Co-PI (if applicable), and any faculty member to receive financial support.

For each individual, include the signature of the appropriate institutional signing official: UMB: Department Chair or School Dean, if appropriate UMBC: Associate Dean for Research; UMCP: Associate Vice President, Research Development or College Chair. A cover letter template will be included in the email with application link. Note from T4's documentation: In versions prior to 8.

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4. 1. --> The abstract is limited to one page and should include: A brief background of the project; The significance of the proposed research; The unique features, new collaborations, and innovation of the project; The methodology (action steps) to be used; Relevance to the translational nature of the ICTR ATIP Grant Program; Potential for improving the health of patients within the next 3-5 years.

The abstract is not included in the 5-page Research Plan. The abstract should not contain proprietary confidential information. Note from T4's documentation: In versions prior to 8.

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4. 1. --> Specific aims, objectives, or hypotheses Specific aims, objectives, or hypotheses must be limited to one page.

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--> The research plan is limited to five pages and should include the following sections: Brief Introduction: This section is intended to help orient the reviewers to better understand the scientific basis for the project, why the work is being proposed as well as the suitability of the research for ATIP Grant funding. Any new collaborations or highly innovative aspects should be succinctly noted.

Relevance to the translational nature of the ATIP program should also be indicated. Project Milestones and Timeline: Submissions must include a timeline of one or more milestones for each Specific Aim with clear outcome endpoints. The timeline must be feasible within the funding period May 1, 2027 – April 30, 2028, and the approved final budget.

This summary may be presented as a chart, a paragraph, or incorporated throughout the experimental design. Milestones should highlight specific goals to be attained relative to the specific aims and, when appropriate, hypotheses to be tested. Milestones must include both the scientific objectives of the application and the procedural issues involved in executing them in a realistic and achievable way.

If new techniques, new populations, or new collaborations are utilized to reach these milestones, they should be emphasized. All grants must be organized towards the completion of project- and/or time- dependent milestones. Quantifiable goals for the completion of each milestone should be delineated.

NOTE : In addition to the milestone/timeline summary presented in the research plan, you must include a Project Milestone Timeline document ( see Project Milestone Timeline ). Regulatory submissions are not considered part of the project and cannot be included in the Project Milestone Timeline.

Background (including Preliminary Results, if available), and Significance: In addition to scientific background and significance, this section may indicate how success of the pilot grant will affect subsequent research and how it enhances translation (e.g., from lab to clinic). The material on Significance should indicate relevance to the overall target of clinical translation.

It should also clarify how the research will advance the field and should also discuss the project’s potential for improving the health of patients within the next 3-5 years. Research Design: Method description should be sufficiently detailed to convince reviewers of feasibility and validity. Details should focus on the novel aspects of the project rather than published or standard techniques.

For Studies Including Human Participants, Data, and/or Samples/Specimens: Where appropriate, provide inclusion/exclusion criteria for each study group(s) and each control group(s) (if planned), and briefly outline recruitment, retention, recruitment/study site(s), consenting, and compensation plan for each. A power calculation and statistical plan must be included to support the study hypothesis and/or specific aims.

For human subjects’ research, specify the number of subjects/controls you expect to enroll or include in your analysis, the expected effect size, the power, and the statistical methods you will use with respect to each outcome measure. You must show that your methods for sample size and data analysis are appropriate given your plans for assignment of participants and delivery of intervention.

If using animals, a power calculation must be included to justify the number of animals that will be used. Quantifiable goals for the completion of each milestone should be delineated. For trials that randomize groups or deliver interventions to groups, special methods are required.

Additional information is available at the NIH Research Methods Resources webpage . If you are unsure about a statistical plan, we encourage you to request a ICTR Biostatistics Core consultation . Statement of Collaborative Effort: Include a specific statement on how the collaboration between investigators from each school and/or community partner is necessary to further the proposal's goals.

Include processes for maintaining communication and interactions between the schools and between UMB, UMBC, and/or UMCP. Describe what the roles of each partner will be during project implementation and what are the expected contributions/benefits of the partnership. Anticipated Problems and Possible Solutions: Any anticipated experimental or interpretive problems should be addressed, with alternative approaches described when possible.

The feasibility of using alternative approaches to complete the project within the constraints of the presented ICTR ATIP budget as well as the strict 12-month time limit of this grant must be assured in the application. All risks and drawbacks from using any proposed alternative approach must be addressed, especially if human subjects are involved. The abstract, specific aims, and references are separate from the research plan.

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--> Comprehensive Budget & Detailed Budget Justification Applicants must use the Excel budget template that will be made available with the electronic application. The school affiliation of team members must be noted on the budget template , including the school affiliation of the “to-be-determined” team members. Cross institutional applications must specify which institution will incur each expense listed on the budget.

Where possible, each line item on the budget should be itemized down to the smallest unit cost. For example, if an item costs $300 and you need 10, enter the unit cost and then the number of units instead of just stating $3,000.

A detailed budget justification is required for each line item listed under each of the categories: Personnel/Consultant/Partners, Equipment/Supplies/Services Costs, Travel Costs, Animal Costs, and Participant Costs required to complete the study. For individuals receiving salary support, provide a brief paragraph in the budget justification about their role and qualifications.

Recent, official quotes for budgeted services, supplies, and equipment must be included. The budget MUST include an explanation of other funding sources that will be used to cover costs not covered by ICTR pilot grant funds. Once awarded, ALL changes to the budget must be submitted BEFORE IMPLEMENTATION for review and final approval by the ICTR Leadership Council.

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--> Biographical sketch information Team members include all individuals with a role in the project regardless of whether they will receive salary support, including the PI(s). A biographical sketch using the most recent NIH template version must be provided for the PI(s) and other faculty-level study team members. Resumes (5-page limit each) may be used for non-faculty team members.

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--> Project Milestones Timeline Applicants must use the Word document template that will be made available with the electronic application. The project timeline must include one or more milestones for each Specific Aim described in the research plan and the time required for each activity.

Please note that IRB/IACUC submissions/approvals or subsequent grant applications/planned publications should not be included in this milestones’ timeline. Note from T4's documentation: In versions prior to 8. 4.

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1. --> Reference list may have up to 30 references. Reference list is not counted in the page limit of the research plan.

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--> Applicants are required to submit the contact information of two external reviewers in the electronic application. Please note that faculty members at UMB, UMCP, and UMBC cannot be considered as external reviewers.

Additionally, please do not designate external reviewers that are outside the U.S. Please ensure that no conflict of interest (COI) exists between the reviewers and you, the Co-PI, and Co-Investigator(s) (if applicable), or any other person with a major professional role in your application.

The peer-review system relies on the applicant's professionalism and reviewers to identify any COI that may affect the integrity of the peer-review process ( see Conflicts of Interest (COI) ). Examples of a reviewer COI: The reviewer is planning a collaboration with anyone with a major professional role on your application or another application in this round.

Within the past three years , the reviewer has published with, has collaborated with, or has been in a mentoring relationship with any person on the application who has a major professional role. The application includes a letter of support or reference letter from the reviewer. The reviewer is an advisor for the proposal under review or for a grant held by anyone playing a major professional role on the application.

The reviewer has an indirect financial interest: The reviewer will have received more than $10,000 (in the form of honoraria, stocks, or fees) from you over the period from one year ago through the end of the proposed project. The reviewer has an indirect financial interest of less than $10,000.

The reviewer freely donates reagents or other materials to the proposed project, and these reagents or materials would also be available to other researchers. The reviewer, you, and a person with a significant role on the proposed project, contribute data, reagents, specimens, etc., to the same repository or database. The reviewer is a member