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Find similar grantsAdvanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research is sponsored by National Cancer Institute (NCI). R33 supports advanced development and validation of emerging technologies for cancer early detection, screening, diagnosis, and related research.
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Opportunity Listing - Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed) Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed) Agency: National Institutes of Health Assistance Listings: 93.
394 -- Cancer Detection and Diagnosis Research Last Updated: June 3, 2026 View version history on Grants.
gov Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites grant applications proposing exploratory research projects focused on further development and technical validation of emerging technologies offering novel capabilities for the molecular or cellular characterization of cancer or for improved handling and quality control of biospecimens used for basic, clinical, or epidemiological cancer research.
This NOFO solicits R33 applications where major feasibility gaps for the technology or methodology have been overcome, as demonstrated with supportive preliminary... data, but still require further development and rigorous technical validation to encourage adoption by the research community.
Well-suited applications must propose the development of technologies that offer the potential to accelerate and/or enhance research in the areas of cancer biology, early detection and screening, clinical diagnosis, treatment, cancer control, epidemiology. Technologies proposed for development may have potential for widespread applicability but must be focused in this proposal on cancer-relevant use cases.
Projects proposing to apply or use existing technologies for hypothesis-driven research where the novelty resides in the biological or clinical target/question being pursued are not responsive to this solicitation and will not be reviewed. This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program.
For-profit organizations other than small businesses Federally recognized Native American tribal governments Special district governments City or township governments Public and Indian housing authorities Nonprofits non-higher education with 501(c)(3) Nonprofits non-higher education without 501(c)(3) Other Native American tribal organizations Independent school districts Public and state institutions of higher education Private institutions of higher education Refer to Section III.
Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.
Foreign components, as defined in the NIH Grants Policy Statement, are allowed. Grantor contact information National Cancer Institute (NCI) File name Description Last updated RFA-CA-27-002-Full-Announcement. html RFA-CA-27-002-Full-Announcement.
html Link to additional information Closing: November 10, 2026 Funding opportunity number : Cost sharing or matching requirement : Funding instrument type : Opportunity Category Explanation : Category of Funding Activity : Your account requires additional identity verification.
According to the current listing, eligibility includes: US institutions and investigators with preliminary data on technology feasibility. Confirm the full requirements in the official notice before applying.
The current listing shows varies (up to ~$300k-$5.9M program total). Verify award ceilings, matching requirements, and allowable costs in the official notice.
Applications for Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research are due November 10, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research is funded by National Cancer Institute (NCI). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
On May 21, 2026, the National Cancer Institute posted RFA-CA-27-006, RFA-CA-27-007, and RFA-CA-27-008 — the three competitive renewals for the NCI Community Oncology Research Program. Combined FY 2027 commitments reach $147.5 million across roughly 57 awards: $74.5 million for up to 7 Research Bases, $73 million for up to 50 Community and Academic Community Sites. Pre-application webinars run June 16-18 this week. Applications are due August 18, 2026 with six-year project periods. For community hospitals, oncology consortia, and NCI-designated cancer centers, this is the single largest cancer clinical-trials infrastructure decision NCI makes until 2033.
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