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Find similar grantsAdvanced Research Projects Agency for Health (ARPA-H) Program is sponsored by National Institutes of Health (NIH). Supports high-risk, high-reward research projects in health, including AI/ML applications in drug discovery.
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The future of health isn’t waiting, and neither are we Investing in the biggest challenges to deliver the greatest impact. Explore Program Portfolio Our mission is simple: solve the most significant health challenges facing Americans today — the ones that are deemed too big, too complex, and too high-risk for traditional funding or industry.
At ARPA-H, we don’t just fund research — we build programs, remove barriers, and accelerate innovations that have the potential to change lives. Our ruthless pursuit of the impossible will create the healthcare solutions that are just waiting to exist.
Hard problems, high-impact answers ARPA-H makes pivotal investments in breakthrough technologies and broadly applicable platforms, capabilities, resources, and solutions with the potential to transform important areas of medicine and health that cannot readily be accomplished through traditional research or commercial activity. ARPA-H solutions aim to benefit everyone.
Expanding what’s technically possible Reaching everyone quickly Keeping people from being patients Building integrated health care systems Investing in transformative health solutions Explore our portfolio of high-impact research programs that are pushing the boundaries of what’s possible in health and medicine. What if we could verify the quality and safety of every dose of every medicine, every time?
Fast Assessment of Solutions, Therapeutics, Pharmaceuticals, and Supplies What if sleep were a controllable biological system—one we could measure, personalize, and optimize to improve health? Restorative and health-Enhancing Sleep Time What if we could make biomedical research faster and more rigorous? Intelligent Generator of Research What if your brain could hear what your ears cannot?
Hearing Enhancement through Artificially Intelligent NeurotechnoloGy What if we could detect, understand the health impacts of, and remove toxic microplastics from the body? Systematic Targeting Of MicroPlastics What if discreet and low-cost wearable devices could help Americans continuously track deep biological information?
Developing self-monitoring ecosystems to “know thyself” What if we could harness the immune system using AI for faster and better critical care? Critical Illness Immunological Reprogramming and Control Point Learning Engine What if we could detect and repair the earliest stages of protein dysfunction to eliminate neurodegenerative disease?
BIOmolecular Grammar for protein Aggregation Modulation and Intervention ARPA-H announces new head of commercialization services ARPA-101: How to deliver healthcare breakthroughs in years AI and Biomedical Discovery: From data to better health outcomes ARPA-H awards to advance personalized curative medicines for rare genetic diseases How ARPA-H is revolutionizing indoor air quality—and why it can’t wait ARPA-H selects pioneering teams to make America the safest place in the world to have a baby ARPA-H 101: Understanding proposal evaluation criteria ARPA-H launches program to redefine sleep as a measurable, controllable driver of health
According to the current listing, eligibility includes: Academic institutions, nonprofit organizations, and small businesses. Confirm the full requirements in the official notice before applying.
Advanced Research Projects Agency for Health (ARPA-H) Program is funded by National Institutes of Health (NIH). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
PA-27-037 consolidates the Predoctoral to Postdoctoral Transition Award into a single parent announcement across 20 NIH components, with the next deadline December 8, 2026. The eligibility gate is not the science — it is a mandatory change of institution and mentor between the F99 and K00 phases.
Read articleA draft executive order would have put OMB Director Russell Vought on a commission with final say over NIH awards after peer review. Sen. Collins killed it by pointing at a provision Congress already passed. Here is what the episode teaches applicants about the December 11 cliff.
Read articlePA-27-034, PA-27-035 and PA-27-036 replace the institute-specific R25 announcements that research education programs have been built around for a decade. NCI, NIDA and NIGMS have already expired theirs early. Here is what the consolidation actually changes: an 8% indirect cost ceiling, a US-citizens-and-permanent-residents participant rule, a cooperative agreement variant that only exists on one of the three, and no clinical-trial-allowed companion anywhere.
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