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Air Force Medical Research and Development is sponsored by DEPT OF DEFENSE. To enhance the health, safety, readiness, and performance of Air Force personnel through applied medical research and advanced development executed largely through grants, cooperative agreements, and contracts with civilian educational and research institutions/organizations. This listing is currently active.
Program number: 12. 810. Last updated on 2026-01-21.
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As a part of the Air Force Research Laboratory (AFRL), AFOSR's technical experts foster and fund research within AFRL, universities, and industry laboratories to ensure the transition of research results to support USAF needs. To accomplish this task, AFOSR solicits proposals for research through various Broad Agency Announcements (BAAs) as well as various other programs outlined below.
**Broad Agency Announcements** Broad Agency Announcements are used to communicate the needs and interests of AFOSR. AFOSR keeps specific requirements of each BAA up-to-date on Grants. gov, the United States government's one source to find and apply for federal grants.
See the latest BAAs. The Scientific and Technology Departments of AFOSR, Business Integration Department (RP), and the International Office (IO) are responsible for the management of several programs that improve science and engineering education in the U.S., and stimulate interactions between Air Force researchers and the broader international, as well as domestic, research community.
Applications for these programs do not always require proposals but generally have specific deadlines, formats, and qualifications. Researchers applying for these programs should communicate with the point-of-contact (POC) listed in each program description.
* Air Force Visiting Scientist Program * Awards to Stimulate and Support Undergraduate Research Experiences (ASSURE)") * Engineer and Scientist Exchange Program (ESEP) * AFRL Science and Technology Fellowship Program (STFP) * USAF-Summer Faculty Fellowship Program (SFFP)") * Window on Science (WOS) Program * Windows on the World (WOW) Program AFOSR provides support for research and education through the following additional programs: * Historically Black Colleges and Universities and Minority Institutions (HBCU/MI) Program * Young Investigator Research Program (YIP) * Small Business Technology Transfer Program (STTR) * AFRL/AFOSR Center of Excellence **University Research Initiative (URI) Programs** The URI programs are executed under the policy guidance of the Office of the Deputy Under Secretary of Defense for Laboratories and Basic Research, to enhance universities' capabilities to perform basic science and engineering research and related education in science and engineering areas critical to national defense.
* Defense University Research Instrumentation Program (DURIP)") * Multidisciplinary Research Program of the University Research Initiative (MURI)") * National Defense Science and Engineering Graduate (NDSEG) Fellowship Program Fellowship Program") * Presidential Early Career Award in Science & Engineering (PECASE)")
According to the current listing, eligibility includes: Applicants must be an institution/organization. Applications will not be accepted from individuals. Eligible applicant types include: Nonprofit Organization. Confirm the full requirements in the official notice before applying.
Yes — Air Force Medical Research and Development is offered by DEPT OF DEFENSE and this listing comes from SAM.gov, an official U.S. federal source. Federal applications generally require registrations (for example SAM.gov or an agency submission portal), so allow extra lead time.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Past winners and funding trends for this program
The U.S. Department of Defense issued 37,285 awards totaling roughly $44.5 billion to 2,814 recipients from FY2021 through FY2025, with a median award of $150,000. The National Center for Manufacturing Sciences ($2.74 billion) and the Henry M. Jackson Foundation for the Advancement of Military Medicine ($2.22 billion) led all recipients, and 58 percent of recipients won more than one separate award.
| Organization | Total awarded |
|---|---|
| National Center for Manufacturing Sciences INC(MI) | $2.7B |
| The Henry M. Jackson Foundation for the Advancement of Military Medicine, INC.(MD) | $2.2B |
| Mississippi Military Department(MS) | $651.5M |
| Bioindustrial Manufacturing and Design Ecosystem(CA) | $538.3M |
| California Military Department(CA) | $525.8M |
| Colorado State University(CO) | $464.5M |
| Pennsylvania Department of Military & Veterans Affairs(PA) | $419.7M |
| Massachusetts Institute of Technology(MA) | $396.7M |
Linked organizations have Granted profiles. Top recipients of U.S. Department of Defense assistance awards, FY2021–FY2025, ranked by total obligations (CFDA 12.x). Source: USAspending. Last verified July 2026.
Congressionally Directed Assistance is sponsored by DEPT OF DEFENSE. To implement Congressionally directed assistance for the purposes identified in the Department of Defense (“DoD”) annual appropriations act. The resulting assistance instruments support a variety of Congressional priorities. DoD awards the appropriate assistance instruments for the Congressionally identified purposes consistent with its authority, including applicable requirements for merit-based or competitive processes. This listing is currently active. Program number: 12.599. Last updated on 2026-01-20.
Uniformed Services University Medical Research Projects is sponsored by DEPT OF DEFENSE. The mission of the Uniformed Services University of Health Sciences is to educate, train, and comprehensively prepare uniformed services health professionals, scientists, and leaders to support the Military and Public Health Systems, the National Security and National Defense Strategies of the United States, and the readiness of our Uniformed Services. The Research Support Division is responsible for grant and cooperative agreement execution as codified in 10 USC 2358 and 10 USC 2113(g). The Division proactively leads the grants/cooperative agreements process - announcing, awarding, and administering grants/cooperative agreements - advancing the Agency’s mission to serve the University’s students, faculty, and staff. This listing is currently active. Program number: 12.750. Last updated on 2026-01-21.
Air Force Defense Research Sciences Program is sponsored by DEPT OF DEFENSE. To maintain technological superiority in the scientific areas relevant to Air Force needs; to prevent technological surprise to our nation and create it for our adversaries; to maintain a strong research infrastructure composed of Air Force laboratories, industry, and universities; and to complement the national research effort. This listing is currently active. Program number: 12.800. Last updated on 2026-01-21.
DoD Multidisciplinary Research Program of the University Research Initiative (MURI) is sponsored by Department of Defense (DoD) - Office of Naval Research (ONR). The Multidisciplinary Research Program of the University Research Initiative (MURI), administered by the Department of Defense Office of Naval Research, supports basic research in science and engineering at U. S.
SBIR SF254-D1206: Knowledge-Guided Test and Evaluation Frameworks for proliferated Low Earth Orbit Constellations is sponsored by U.S. Air Force. DOD SBIR topic SF254-D1206: Knowledge-Guided Test and Evaluation Frameworks for proliferated Low Earth Orbit Constellations. Component: U.S. Air Force. Command: SDA. Solicitation: DoD SBIR 2025.4. Phase(s): D2PII, II, SPII. Status: Pre-Release. Open date: 3/4/2026.
The Defense Production Act's Title III has quietly become one of the most active federal funding vehicles of 2026 — $500M for energy infrastructure, ~$275M for critical-minerals processing, and a standing defense-manufacturing FOA. But the underlying authorities sunset September 30, 2026 absent reauthorization. Here is how DPA Title III works, who is eligible, why it differs from a normal grant, and how to move before the window closes.
Read articleTitle III of the Defense Production Act lets the Pentagon hand non-dilutive capital to companies that expand domestic production of defense-critical materials and manufacturing — through a white-paper-first pathway run by the Air Force Research Laboratory (FA8650-19-S-5010) rather than a conventional grant competition. But the core DPA authorities sunset September 30, 2026 absent reauthorization, and the standing white-paper window has moved in and out of suspension. Here is how the Title III mechanism actually works, why it rewards companies that lead with a supply-chain vulnerability, and how to position before the authority cliff.
Read articleThe Department's FY26 SBIR/STTR Release 3 opened June 24 with roughly 37 topics across DARPA, the Navy, the Air Force, and the defense components, all closing July 22. The compressed four-week window is unforgiving, but the bigger mistake founders make is treating every component the same. Here is how to read the release, the eligibility rules that disqualify good companies, and why the component you target matters more than the topic you pick.
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