America First Global Health Strategy Bilateral Health Cooperation Agreements (Multiple African Countries)

America First Global Health Strategy Bilateral Health Cooperation Agreements (Multiple African Countries) is sponsored by U.S. Department of State. The U. S.

Department of State has signed bilateral health cooperation agreements with multiple African countries.

KFF Tracker: America First MOU Bilateral Global Health Agreements | KFF KFF Tracker: America First MOU Bilateral Global Health Agreements Editorial Note: Originally published on January 13, 2026, this resource will be updated as needed, most recently on April 27, 2026, to reflect additional developments.

On September 18, 2025, the U.S. government (USG) released its new America First Global Health Strategy , which details how the U.S. will engage in global health efforts moving forward. As part of this new strategy, the U.S. has announced that it will be establishing bilateral health cooperation agreements with countries that receive U.S. global health assistance.

These agreements, or Memorandums of Understanding (MOUs), between the U.S. and partner countries represent five-year plans (for the period 2026-2030) outlining U.S. engagement in each country’s health efforts with the goal of “helping countries move toward more resilient and durable health systems.

” Central to these plans is transitioning country programs from U.S. assistance to long-term country ownership, with a pledge from each partner country to increase its domestic health spending, or co-investment in health, over the next five years as the U.S. decreases its health assistance. The U.S. began signing these agreements in late 2025 and this process is ongoing. Implementation is slated for later this year.

This tracker provides information on U.S. MOU bilateral global health agreements to date. Information is sourced from publicly available U.S. Department of State, U.S. embassies, and partner country Ministries of Health press release statements and MOU texts, and will be updated as more information becomes available and when additional agreements are signed.

Currently, MOU text, which contains the most detailed information of these sources, is publicly available for only a limited number of countries; for these countries, data were sourced directly from these MOU documents. For countries with available MOU documents, overall totals are based on the sum of annual amounts presented in the text.

Program areas are captured using keyword searches; for global health security (GHS) specifically, country agreements were categorized as targeting GHS if they specifically mentioned GHS, or if they included descriptions of outbreak preparedness and response activities and containing health threats.

Due to the limited nature of press release statements, this tracker may not comprehensively capture the global health program areas targeted in each country’s agreement. U.S. Global Health Country-Level Funding Tracker The Trump Administration’s Foreign Aid Review: Reorganization of U.S. Global Health Programs Questions for the America First Global Health Strategy