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Amyotrophic Lateral Sclerosis Research Program (ALSRP) Clinical Outcomes and Biomarkers Award (COBA) is sponsored by Department of Defense (DoD), Congressionally Directed Medical Research Programs (CDMRP). Supports the development and/or validation of clinical outcomes and biomarkers to enrich clinical trials in Amyotrophic Lateral Sclerosis (ALS).
Projects can be relevant to a specific therapy, a class of therapeutics, or to a specific ALS subtype.
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You are using an outdated browser. Please upgrade your browser to improve your experience. U.S. Department of War organization.
Due to routine system maintenance the CDMRP website will be unavailable from COB 24 April - 27 April COB.
DEPARTMENT OF WAR - CONGRESSIONALLY DIRECTED MEDICAL RESEARCH PROGRAMS Transforming Health Care through Innovative and Impactful Research Amyotrophic Lateral Sclerosis Research Program FY26 Amyotrophic Lateral Sclerosis Research Program (ALSRP) Synopsis of FY26 ALSRP Award Mechanisms - (Adobe PDF) - provides a brief description and key elements of the award mechanism.
Program Announcement/Instructions Clinical Outcomes and Biomarkers Award Pre-Application (Preproposal): June 24, 2026 5:00 p. m. Eastern Time September 30, 2026 11:59 p.
m. Eastern Time Pilot Clinical Trial Award Pre-Application (Preproposal): June 24, 2026 5:00 p. m.
Eastern Time September 30, 2026 11:59 p. m. Eastern Time Therapeutic Development Award Pre-Application (Preproposal): June 24, 2026 5:00 p.
m. Eastern Time September 30, 2026 11:59 p. m.
Eastern Time Pre-Application (Preproposal): June 24, 2026 5:00 p. m. Eastern Time September 30, 2026 11:59 p.
m. Eastern Time For further information, please send e-mail to: CDMRP Webmaster - for download-related questions Help@ebrap. org - for program announcement-related questions Last updated Thursday, August 6, 2026
According to the current listing, eligibility includes: Independent investigators - Faculty with PI eligibility and CE faculty (with an approved CE faculty PI waiver obtained through their RPM in RMG prior to the pre-application/letter of intent) may be PI. Confirm the full requirements in the official notice before applying.
Amyotrophic Lateral Sclerosis Research Program (ALSRP) Clinical Outcomes and Biomarkers Award (COBA) is funded by Department of Defense (DoD), Congressionally Directed Medical Research Programs (CDMRP). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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