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The purpose of this Notice of Funding Opportunity (NOFO) is to advance efforts for a nationally integrated animal food safety system providing state animal food regulatory programs the ability to achieve full implementation of the Animal Food Regulatory Program Standards (AFRPS) within 5 years and to maintain full implementation. This NOFO will also fund optional projects for state animal food regulatory programs to:Advance food safety and protect public health by strengthening partnerships with the FDA and other state animal food regulatory partners through sharing, collaboration, coordination, and leveraging each other’s expertise, work, data, and enforcement actions.Develop and standardize processes, procedures, systems, and other methods to integrate federal and state animal food regulatory work resulting in mutual reliance.Specific outcomes may include, but are not limited to:State animal food regulatory programs will achieve and maintain implementation of the AFRPS, which is recognized as a critical element to creating a national, fully integrated food safety system.Operational use of standardized animal food regulatory systems developed by state programs to compel federal reliance on state regulatory work and resources and reciprocal state reliance on federal work and resources, resulting in mutual reliance.This project will strengthen and improve FDA efforts to build an integrated food safety system by building high quality state animal food regulatory programs that can promote regulatory compliance and prevent foodborne illnesses.
Funding Opportunity Number: PAR-25-003. Assistance Listing: 93.103. Funding Instrument: CA. Category: AG,CP,FN. Award Amount: Up to $300K per award.
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Or search similar grants →According to the current listing, eligibility includes: Eligible applicants: State governments. The eligibility for this opportunity is limited to State animal food safety programs meeting the following criteria:Applicants must maintain an FDA inspectional contract in good standing by completing all agreed upon inspectional work, audits, and associated compliance and regulatory activities. The contract must include performing comprehensive animal food inspections under 21 CFR Part 507 that is representative of the state's firm inventory and supports the FDA and state regulatory program in meeting a risk-based inspection frequency. The contract should result in a minimum of 10% of the firm inventory regulated by the FDA being inspected for all applicable regulations.Applicant organizations must have a valid 20.88 agreement with FDA prior to the time of application.Applicants will be categorized under one of two funding tracks: AFRPS Development or AFRPS Maintenance (see eligibility criteria above. Within the AFRPS Maintenance funding track only, an applicant may apply to the Mutual Reliance funding option, provided they meet the funding option eligibility criteria (below).Applicants are encouraged to apply for cooperative agreement assistance that reflects their jurisdiction's needs in terms of amounts of funding and number of project years.To ascertain an applicant's tier funding level, please consult Section II. Award Information.Funding Track 1: AFRPS Development PhaseApplicants must have received less than five (5) years of funding under a past AFRPS cooperative agreement, or have never received an AFRPS cooperative agreement. Applicants may request up to $300,000 per year for this funding track. State programs will move to AFRPS Maintenance funding levels in the sixth year of funding under AFRPS cooperative agreements. Applicants with less than five (5) years of funding under a past AFRPS cooperative agreement may elect to count years of AFRPS enrollment under the FDA Animal Food Safety Inspection Contract toward the five (5) years AFRPS funding eligibility requirement when determining the entry date for Funding Track 2 (AFRPS Maintenance Phase), and may elect to move to Funding Track 2 (AFRPS Maintenance Phase) for the award year after full implementation of the AFRPS has been achieved (as determined by an assessment by FDA Audit Staff).Funding Track 2: AFRPS Maintenance PhaseApplicants must have received five (5) years of funding under a past AFRPS cooperative agreement. Applicants with less than five (5) years funding under a past AFRPS cooperative agreement may elect to count years of AFRPS enrollment toward the five (5 years AFRPS funding eligibility requirement when determining the entry date for Funding Track 2 (AFRPS Maintenance Phase), and may elect to move to Funding Track 2 (AFRPS Maintenance Phase for the award year after full implementation of the AFRPS has been achieved (as determined by an assessment by FDA Audit Staff). If the state program is not currently deemed to be in full implementation and their corrective actions are still pending (in response to the most recent assessment by FDA Audit Staff), then the program must address the corrective actions in their strategic improvement plan submitted as part of the application.Applicants have been classified into three (3) levels of funding levels based on a variety of factors unique to that jurisdiction (See data sources below). This approach establishes funding levels proportional to the applicant's jurisdictional work volume and costs for this program area. To determine which funding level is applicable to your program, please consult the table below. Applicants are encouraged to apply for cooperative agreement assistance that reflects their jurisdiction's needs both in terms of amounts of funding and number of project years.Funding Track 3 (Optional): Mutual RelianceApplicants must be recognized as being in full implementation by the FDA audit staff prior to the time of application. Confirm the full requirements in the official notice before applying.
The current listing shows up to $300K per award. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Applications for Animal Food Regulatory Program Standards Implementation Development and Maintenance, with Mutual Reliance Initiatives Clinical Trials Not Allowed are due April 1, 2027. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
Yes — Animal Food Regulatory Program Standards Implementation Development and Maintenance, with Mutual Reliance Initiatives Clinical Trials Not Allowed is offered by Food and Drug Administration and this listing comes from Grants.gov, an official U.S. federal source. Federal applications generally require registrations (for example SAM.gov or an agency submission portal), so allow extra lead time.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Past winners and funding trends for this program
The Food and Drug Administration made 1,737 awards worth roughly $1.1 billion to 361 recipients in FY2021-2025, with a median award of $248,122. The Critical Path Institute ($59.7 million) and the National Environmental Health Association ($55.4 million) were the largest recipients, and 66 percent of recipients won more than one separate award.
| Organization | Total awarded |
|---|---|
| The Critical Path Institute(AZ) | $59.7M |
| National Environmental Health Association(CO) | $55.4M |
| Association of Food & Drug Officials(PA) | $50.2M |
| The Medical Device Innovation Consortium(VA) | $48.6M |
| Duke University(NC) | $34.7M |
| Food & Agriculture, California Department of(CA) | $23.2M |
| Regents of the University of California, San Francisco, the(CA) | $21.6M |
| University of Maryland, Baltimore(MD) | $20.7M |
Linked organizations have Granted profiles. Top recipients of Food and Drug Administration (FDA) assistance awards, FY2021–FY2025, ranked by total obligations (CFDA 93.x · Food and Drug Administration). Source: USAspending. Last verified July 2026.
This Funding Opportunity Announcement (FOA) issued by the Food and Drug Administration (FDA), Center for Veterinary Medicine (CVM), builds upon the National Antimicrobial Resistance Monitoring System (NARMS) which was initiated in 1996 as one of the key activities in a national action plan to combat antibiotic resistance threats. The purpose of this FOA is to protect and promote public health by enhancing, strengthening, and sustaining antibiotic resistance surveillance in retail food specimens within the NARMS program. The NARMS cooperative agreement is intended to improve the detection of antibiotic resistance among bacteria in food commodities, as well as expand to new sites to expand the scope of sampling. Measurable outcomes of the program will be in alignment with the NARMS Objectives. Funding Opportunity Number: PAR-25-014. Assistance Listing: 93.103. Funding Instrument: CA. Category: AG,CP,FN. Award Amount: Up to $200K per award.
This cooperative agreement is intended to enhance the capacity and capabilities of state human and animal food testing laboratories in support of an integrated food safety system (IFSS). This is achieved through prioritized sample testing and food defense preparedness in the areas of microbiology, chemistry, and radiochemistry, as well as method development and capacity/capability development projects that support and expand food safety and food defense testing. Funding Opportunity Number: RFA-FD-25-007. Assistance Listing: 93.103. Funding Instrument: CA. Category: AG,CP,FN. Award Amount: Up to $1.5M per award.
Reissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional) is sponsored by Food and Drug Administration. The purpose of this notice of funding opportunity (NOFO) is to support efficient and innovative natural history studies that advance medical product development in rare diseases/conditions with unmet needs.
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