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ARPA-H CATALYST Program for AI-Powered Computational Drug Safety and Efficacy Prediction is sponsored by Advanced Research Projects Agency for Health (ARPA-H). The ARPA-H CATALYST (Computational ADME-Tox and Physiology Analysis for Safer Therapeutics) program leverages artificial intelligence and machine learning to develop computational models that mimic real human biology to predict drug safety and effectiveness for Investigational N…
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Or search similar grants →According to the current listing, eligibility includes: Open to academic institutions, private companies, medical centers, and research organizations. Awards are made through Other Transaction Agreements (OTAs). Confirm the full requirements in the official notice before applying.
The current listing shows total program funding up to $125 million over 4.5 years. Individual performer team awards range from approximately $21 million to $31.7 million, contingent on meeting aggressive milestones. Eight performer teams selected across academia and industry. Verify award ceilings, matching requirements, and allowable costs in the official notice.
ARPA-H CATALYST Program for AI-Powered Computational Drug Safety and Efficacy Prediction is funded by Advanced Research Projects Agency for Health (ARPA-H). Verify program details on the funder's official page before applying.
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ARPA-H's 2026 SBIR/STTR BAA opens seven transformative health topics with $600K Phase I and $3.5M Phase II contracts — non-dilutive, milestone-driven money. The July 10 Solution Summary gate decides who ever gets to pitch. Here's how the ARPA-H model differs from NIH and how small health-tech firms actually get through the funnel.
Read articleARPA-H's FY2026 SBIR/STTR solicitation closes its Solution Summary stage July 10, with seven named topics spanning women's health, autoimmune diagnostics, toxin removal, and neurosurgical robotics. Awards run up to $600K for Phase I and $3.5M for Phase II — but they are contracts, not grants, and the four-to-six-page summary is the gate that filters out most applicants. Here is how ARPA-H's model actually works and how to win the first stage.
Read articleARPA-H's FY2026 SBIR/STTR solicitation opens with a Solution Summary due July 10, 2026, then a Technical Oral Presentation by September 9 for those invited. Awards run up to $600K (Phase I) and $3.5M (Phase II), with Direct-to-Phase-II and Fast Track options across seven health topic areas. Here is how the two-step, pitch-driven process differs from NIH SBIR — and how to win the first gate.
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