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Open Office BAA replaced by Mission Office ISOs; see ARPA-H site for current solicitations.
Historical funding: $500,000 - $15,000,000
Prior eligibility: Higher Education, Nonprofits, For-profit Organizations, Small Businesses
ARPA-H Open Office Broad Agency Announcement is a grant from the Advanced Research Projects Agency for Health (ARPA-H) that supports high-impact, innovative health research aimed at solving complex challenges traditional research and private industry cannot address alone. Through diverse funding mechanisms including programs, initiatives, and small business SBIR/STTR awards, ARPA-H invests in transformative science to improve health outcomes at scale. Current solicitations include BioStabilization Systems (BoSS), Critical Illness Immunological Reprogramming (CIRCLE), and the Delphi self-monitoring ecosystem project. Mission Office Innovative Solution Openings (ISOs) accept rolling applications for individual research projects outside existing program scopes. Applicants must align with ARPA-H's research focus areas and submit a Solution Summary before a full proposal.
CMS awarded the entire $50 billion Rural Health Transformation Program to all 50 states, with first-year checks averaging $200M per state and money starting to move October 1, 2026. The federal contest is over — but for rural hospitals, clinics, behavioral-health providers, and nonprofits, the real competition is just beginning inside each state's sub-grant process. Here is how the money splits, what it can fund, and how to position now.
Read articleCMS awarded all 50 states their first-year slice of the $50 billion Rural Health Transformation Program in December 2025 — from $147M in New Jersey to $281M in Texas. Now the money is moving downstream: New Jersey and New York have already launched subaward RFAs, and rural hospitals, clinics, community organizations, and tribal groups are the eligible applicants. Here is how the allocation formula worked, what the money can and cannot fund, and the strategy to win a state subaward.
Read articleThe FY2026 Rural Health Network Advancement Program (HRSA-26-082) offers six awards of roughly $500,000 to help independent rural hospitals and clinics form integrated networks without surrendering local ownership. With a July 24, 2026 deadline and a pilot design that rewards genuine collaboration over merger, here is who qualifies, what a fundable network looks like, and how small rural providers should approach it.
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